PTPN5

Gene Name		protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
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Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Phosphotyrosine Binding Protein Tyrosine Phosphatase Activity
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065)
Protein-protein Interactions		11 interactors: CUL5 CXCL9 FAM58A FYN MAPK1 MAPK3 SNX4 TERF1 TMEM51 VTI1B ZBTB5
Entrez ID		84867
HPRD ID		01472
Ensembl ID		ENSG00000110786
Uniprot IDs		B7Z2F8 B7ZAF5 P54829 Q86TL3
PDB IDs		2BIJ 2BV5 2CJZ
Enriched GO Terms of Interacting Partners?		Regulation Of Golgi Inheritance Caveolin-mediated Endocytosis Regulation Of Cellular Localization Regulation Of Golgi Organization Sensory Perception Of Pain Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Early Endosome To Late Endosome Transport Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Immune System Process Regulation Of Intracellular Transport Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Cellular Response To Fibroblast Growth Factor Stimulus Response To Epidermal Growth Factor Viral Process Platelet Activation Response To Fibroblast Growth Factor Regulation Of Cellular Response To Heat Regulation Of Cellular Component Organization Neurotrophin TRK Receptor Signaling Pathway Chemotaxis Lipopolysaccharide-mediated Signaling Pathway Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Signal Transduction Positive Regulation Of Immune Response Response To Growth Hormone Regulation Of Immune System Process Phagocytosis Response To Exogenous DsRNA Fc Receptor Signaling Pathway Cell Proliferation Immune Response-activating Cell Surface Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway JAK-STAT Cascade Vesicle-mediated Transport Toll-like Receptor 10 Signaling Pathway Cellular Response To Peptide Hormone Stimulus Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Lipopolysaccharide Toll-like Receptor 2 Signaling Pathway
Tagcloud ?		ad aggregated aggregates amyloid beneficial biology burden called discovery disrupts economic enriched hyperphosphorylated making millions modulating neurofibrillary neuropathology nfts plaques representing reviews step striatal substantial tangles trafficking turn worldwide