LDB1 and SSBP2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LDB1	SSBP2
Gene Name		LIM domain binding 1	single-stranded DNA binding protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex Protein Complex	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Enhancer Sequence-specific DNA Binding Chromatin Binding Transcription Corepressor Activity Enzyme Binding LIM Domain Binding Protein Homodimerization Activity Protein Self-association	Single-stranded DNA Binding
	Biological Process	Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Gastrulation With Mouth Forming Second Hair Follicle Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Anterior/posterior Axis Specification Epithelial Structure Maintenance Wnt Signaling Pathway Cerebellar Purkinje Cell Differentiation Cellular Component Assembly Neuron Differentiation Regulation Of DNA-templated Transcription, Elongation Somatic Stem Cell Maintenance Histone H3-K4 Acetylation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hemoglobin Biosynthetic Process	Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Anorexia nervosa ( 21079607) Glioblastoma ( 22472174)
Protein-Protein Interactions		26 interactors: ATXN1 CTDSP1 ESR1 IRAK3 ISL1 LHX2 LHX3 LHX6 LHX8 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP	6 interactors: CDK6 EWSR1 IL36RN LDB1 LDB2 TOM1
Entrez ID		8861	23635
HPRD ID		09144	09577
Ensembl ID		ENSG00000198728
Uniprot IDs		Q86U70	P81877
PDB IDs		2XJY 2XJZ 2YPA
Enriched GO Terms of Interacting Partners?		Gene Expression Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Central Nervous System Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Central Nervous System Development Cellular Metabolic Process Brain Development Head Development Developmental Process Organ Development Anatomical Structure Development Forebrain Development Tube Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Specification Process Cell Differentiation Negative Regulation Of Signal Transduction Multicellular Organismal Development Neuron Differentiation Anatomical Structure Morphogenesis System Development Spinal Cord Motor Neuron Differentiation Generation Of Neurons Negative Regulation Of Signaling Transcription From RNA Polymerase II Promoter Neurogenesis	Epithelial Structure Maintenance Regulation Of Erythrocyte Differentiation Stem Cell Differentiation Somatic Stem Cell Maintenance Negative Regulation Of Myeloid Cell Differentiation Hair Follicle Development Hair Cycle Process Histone H3-K4 Acetylation Cell Dedifferentiation Negative Regulation Of Interferon-gamma Secretion Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Hair Cycle Antifungal Humoral Response Positive Regulation Of Hemoglobin Biosynthetic Process Negative Regulation Of Cell Differentiation Stem Cell Maintenance Regulation Of Myeloid Cell Differentiation Tissue Homeostasis Regulation Of Hemoglobin Biosynthetic Process Skin Development Multicellular Organismal Homeostasis Stem Cell Development Epithelium Development Epidermis Development Negative Regulation Of Cellular Senescence Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Interleukin-17 Production Hematopoietic Stem Cell Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Immune System Process Negative Regulation Of Cell Aging Cerebellar Purkinje Cell Differentiation Extracellular Negative Regulation Of Signal Transduction Cerebellar Purkinje Cell Layer Morphogenesis Dentate Gyrus Development Type B Pancreatic Cell Development Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Astrocyte Development Type B Pancreatic Cell Differentiation Negative Regulation Of Receptor Activity Lateral Ventricle Development Enteroendocrine Cell Differentiation Regulation Of Cellular Senescence Tissue Development Cerebellar Cortex Formation Defense Response To Fungus Antimicrobial Humoral Response Cell Development Glandular Epithelial Cell Development
Tagcloud ?		assemble bhlh compatible consensus e12 erythroid erythroleukemia erythropoiesis exist forced g1er hemopoietic immature lbd1 lim lmo2 maintain maturation mediate multiprotein normally oncoprotein others precursors presumed primarily proerythroblast scl whose	abstract aim apc area assessment biomarkers cdkn2a chile cholecystitis cohort curve dna elisa esr1 gallbladder gbc global index material methylation operator pgp9 predictive promoter quantitative receiver specificity technique useful
Tagcloud (Difference) ?		assemble bhlh compatible consensus e12 erythroid erythroleukemia erythropoiesis exist forced g1er hemopoietic immature lbd1 lim lmo2 maintain maturation mediate multiprotein normally oncoprotein others precursors presumed primarily proerythroblast scl whose	abstract aim apc area assessment biomarkers cdkn2a chile cholecystitis cohort curve dna elisa esr1 gallbladder gbc global index material methylation operator pgp9 predictive promoter quantitative receiver specificity technique useful
Tagcloud (Intersection) ?