CCKAR and PPP1R9B

Number of citations of the paper that reports this interaction (PMID 17464283)
18

Data Source:
HPRD (in vitro)

		CCKAR	PPP1R9B
Gene Name		cholecystokinin A receptor	protein phosphatase 1, regulatory subunit 9B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Protein Phosphatase Type 1 Complex Nucleoplasm Cytoplasm Plasma Membrane Adherens Junction Lamellipodium Filopodium Cortical Actin Cytoskeleton Ruffle Membrane Dendritic Spine Synapse
	Molecular Function	Cholecystokinin Receptor Activity Peptide Binding	Actin Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding
	Biological Process	Neuron Migration Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Axonogenesis Response To Nutrient Digestion Feeding Behavior Forebrain Development Cellular Response To Hormone Stimulus Cholecystokinin Signaling Pathway Regulation Of Hormone Secretion Response To Peptide	Regulation Of Cell Growth By Extracellular Stimulus Regulation Of Protein Phosphorylation Actin Filament Organization Cell Cycle Arrest Regulation Of Exit From Mitosis RNA Splicing Dendrite Development Cell Migration Calcium-mediated Signaling Negative Regulation Of Cell Growth Regulation Of Cell Proliferation Negative Regulation Of Catalytic Activity Filopodium Assembly Regulation Of Synaptic Transmission Cellular Response To Morphine Regulation Of Opioid Receptor Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		Ceruletide
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CCK CCKBR PPP1R9B	23 interactors: ACTA1 ADRA1A ADRA1B ADRA2A ADRA2B ADRA2C CCKAR CCKBR CDKN2A CHRM3 DCX DRD2 MAPK1 PPP1CA PPP1CB PPP1CC PPP1R2 PPP1R9A PRKACA RGS2 RPS6KB1 TGOLN2 TIAM1
Entrez ID		886	84687
HPRD ID		00322	04506
Ensembl ID		ENSG00000163394	ENSG00000108819
Uniprot IDs		P32238	D3DTX6 Q96SB3
PDB IDs		1D6G 1HZN 1PB2
Enriched GO Terms of Interacting Partners?		Feeding Behavior Regulation Of Phosphorylation Regulation Of Opioid Receptor Signaling Pathway Cholecystokinin Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Cellular Response To Morphine Regulation Of Cell Growth By Extracellular Stimulus Cellular Response To Isoquinoline Alkaloid Regulation Of Catalytic Activity Response To Extracellular Stimulus Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Appetite Gastric Acid Secretion Regulation Of Exit From Mitosis Behavior Filopodium Assembly Regulation Of Mitochondrial Depolarization Regulation Of Response To Food Positive Regulation Of Protein Oligomerization Cellular Response To Ammonium Ion Regulation Of Appetite Regulation Of Sensory Perception Of Pain Neuron Projection Development Regulation Of Protein Oligomerization Positive Regulation Of Cell Proliferation Cell Migration Eating Behavior Release Of Cytochrome C From Mitochondria Cell Motility Regulation Of Membrane Depolarization Behavioral Fear Response Neuron Development Cellular Response To Alkaloid Response To Morphine Fear Response System Development Regulation Of Protein Phosphorylation Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity Neuron Differentiation G-protein Coupled Receptor Signaling Pathway Cell Projection Organization Regulation Of Neurological System Process Regulation Of Lipid Kinase Activity Acid Secretion Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Locomotion Multicellular Organismal Development Anatomical Structure Development	Energy Reserve Metabolic Process Adrenergic Receptor Signaling Pathway Regulation Of Signaling Regulation Of Muscle Contraction Regulation Of Smooth Muscle Contraction Regulation Of Vasoconstriction Regulation Of Signal Transduction Energy Derivation By Oxidation Of Organic Compounds Signal Transduction Cell Surface Receptor Signaling Pathway Activation Of MAPK Activity By Adrenergic Receptor Signaling Pathway Signaling Cellular Response To Stimulus Regulation Of Phosphorus Metabolic Process Cell Communication Negative Regulation Of Signaling Regulation Of MAPK Cascade Generation Of Precursor Metabolites And Energy Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Epidermal Growth Factor-activated Receptor Transactivation By G-protein Coupled Receptor Signaling Pathway Regulation Of Hormone Secretion Triglyceride Catabolic Process Positive Regulation Of MAPK Cascade Regulation Of Phosphorylation Receptor Transactivation Acylglycerol Catabolic Process Developmental Process Negative Regulation Of Epinephrine Secretion Response To External Stimulus Regulation Of Kinase Activity Intracellular Signal Transduction Positive Regulation Of Intracellular Signal Transduction Regulation Of Glycogen Catabolic Process G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Norepinephrine Secretion Response To Organic Substance Response To Stimulus Positive Regulation Of Signal Transduction Muscle System Process Regulation Of Intracellular Signal Transduction Activation Of Protein Kinase Activity Positive Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Cellular Localization Regulation Of Protein Kinase Activity Regulation Of MAP Kinase Activity System Development Anatomical Structure Development Regulation Of Norepinephrine Secretion Negative Regulation Of Signal Transduction Response To Abiotic Stimulus
Tagcloud ?		afferent amphetamine cart cascades coadministration cocaine colocalization egr electroporation feeding firing ganglia hairpin hypothalamus lentiviral leptin lrbs mediating neurotransmitter ng nodose ope satiety short silencing synergistically vagal	accn1 ago arises cgg description disturbed eef1a2 fmr1 fmrp fragile gabrd hes1 inherited intelligence interactive lending lymphoblastoid lymphoblasts males microarrays morphogenesis neurodevelopment overrepresentation retardation syndrome transcriptome trinucleotide unc13b untranslated
Tagcloud (Difference) ?		afferent amphetamine cart cascades coadministration cocaine colocalization egr electroporation feeding firing ganglia hairpin hypothalamus lentiviral leptin lrbs mediating neurotransmitter ng nodose ope satiety short silencing synergistically vagal	accn1 ago arises cgg description disturbed eef1a2 fmr1 fmrp fragile gabrd hes1 inherited intelligence interactive lending lymphoblastoid lymphoblasts males microarrays morphogenesis neurodevelopment overrepresentation retardation syndrome transcriptome trinucleotide unc13b untranslated
Tagcloud (Intersection) ?