EIF3G and FAM9B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EIF3G	FAM9B
Gene Name		eukaryotic translation initiation factor 3, subunit G	family with sequence similarity 9, member B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Perinuclear Region Of Cytoplasm	Nucleoplasm
	Molecular Function	Nucleotide Binding Translation Initiation Factor Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Formation Of Translation Preinitiation Complex Translation Translational Initiation Regulation Of Translational Initiation Gene Expression Cellular Protein Metabolic Process
Pathways		Ribosomal scanning and start codon recognition Translation initiation complex formation Formation of the ternary complex, and subsequently, the 43S complex GTP hydrolysis and joining of the 60S ribosomal subunit Translation Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Cap-dependent Translation Initiation L13a-mediated translational silencing of Ceruloplasmin expression
Drugs
Diseases
GWAS			Androgen levels ( 22936694)
Protein-Protein Interactions		22 interactors: ACD AIFM1 APP EIF3A EIF3B EIF3C EIF3D EIF3H EIF3K EIF5 EPB41 FAM9B GADD45G GOLGA2 MPHOSPH6 MPP6 PIN1 PKN2 POT1 SMN1 SNCA TK1	118 interactors: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BARD1 BCL2A1 BET1 BLOC1S2 BYSL C12orf10 C14orf105 C16orf72 C19orf57 C20orf195 C8orf33 CADPS CCDC106 CCDC116 CCDC70 CDC23 CDC42EP4 CDCA7L CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G FAM161A FASTKD3 FCHSD2 FERD3L GFOD1 GOPC GPX1 GSTK1 ISCU LIN7A LNX1 LOC728175 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MYO15B NDE1 NDUFB10 NEBL NOL4 PAGE1 PAGE3 PHYH PIN4 POLL PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RPL9 RSL24D1 RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMN2 SNAP29 SNAP47 SNX20 STK3 SUCLA2 SYT17 TBRG4 TCEA2 TCEANC TCEB3 TGFBI TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 XRCC4 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614
Entrez ID		8666	171483
HPRD ID		04886	15955
Ensembl ID		ENSG00000130811	ENSG00000177138
Uniprot IDs		O75821	Q8IZU0 Q8N7Z8
PDB IDs		2CQ0
Enriched GO Terms of Interacting Partners?		Formation Of Translation Preinitiation Complex Regulation Of Translational Initiation Ribonucleoprotein Complex Biogenesis Cellular Component Assembly Regulation Of Translation Posttranscriptional Regulation Of Gene Expression Ribonucleoprotein Complex Assembly Translational Initiation Regulation Of Cellular Protein Metabolic Process Cellular Macromolecular Complex Assembly Regulation Of Protein Metabolic Process Formation Of Cytoplasmic Translation Initiation Complex Translation Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Capping Positive Regulation Of Telomerase Activity Cytoplasmic Translational Initiation Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Cellular Metabolic Process Cytoplasmic Translation Negative Regulation Of Chromosome Organization Regulation Of Binding Regulation Of Telomerase Activity Positive Regulation Of Transferase Activity Maturation Of 5.8S RRNA Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Regulation Of Metabolic Process Response To Copper Ion Positive Regulation Of Catalytic Activity Gene Expression Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Ribosome Biogenesis Protein Metabolic Process Regulation Of Chromosome Organization Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Biosynthetic Process Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation	Mitochondrial Translation Organelle Organization Translational Elongation Vesicle Organization Gene Expression Mitochondrion Organization Synaptic Vesicle Priming Mitochondrial Translational Elongation Translation Establishment Of Vesicle Localization Vesicle Localization Ribonucleoprotein Complex Biogenesis Establishment Of Organelle Localization Cellular Component Assembly Cellular Metabolic Process Synaptic Vesicle Transport Mitochondrial Translational Initiation Mitochondrial Translational Termination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Extracellular Vesicular Exosome Assembly Cellular Macromolecular Complex Assembly Organelle Localization Translational Termination RNA Metabolic Process Translational Initiation Cellular Response To Stress Apoptotic Signaling Pathway Cellular Response To DNA Damage Stimulus Membrane Organization Protein Polyubiquitination Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Cellular Process Cellular Protein Complex Disassembly Intrinsic Apoptotic Signaling Pathway Ribosome Biogenesis Neurotransmitter Secretion Macromolecule Biosynthetic Process Vesicle Fusion Pigmentation Protein Complex Disassembly Synaptic Vesicle Exocytosis Viral Process Cellular Pigmentation
Tagcloud ?		bimolecular c2hc complementation defense eifs enhancing eukaryotic finger fragment hybrid impair interfere machinery motif nia papaya preinitiation pro protoplasts prsv residues ringspot sos translation translational validated yeast zinc
Tagcloud (Difference) ?		bimolecular c2hc complementation defense eifs enhancing eukaryotic finger fragment hybrid impair interfere machinery motif nia papaya preinitiation pro protoplasts prsv residues ringspot sos translation translational validated yeast zinc
Tagcloud (Intersection) ?