MKNK1 and DNAJC7

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		MKNK1	DNAJC7
Gene Name		MAP kinase interacting serine/threonine kinase 1	DnaJ (Hsp40) homolog, subfamily C, member 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Nucleoplasm Cytoplasm Cytoskeleton Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Protein Binding Heat Shock Protein Binding
	Biological Process	Regulation Of Translational Initiation Protein Phosphorylation Fibroblast Growth Factor Receptor Signaling Pathway Response To Salt Stress Peptidyl-serine Phosphorylation Intracellular Signal Transduction Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Protein Folding Chaperone Cofactor-dependent Protein Refolding
Pathways		Signaling by FGFR in disease Spry regulation of FGF signaling Signaling by FGFR Negative regulation of FGFR signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: APP ATXN3 CREBBP DDAH2 DNAJC7 EIF4E EIF4G1 EIF4G2 EIF4G3 FANCA HGS HIPK2 HSP90AB1 MAPK1 MAPK14 MAPK3 MBP PAK2 PHAX PLA2G4A PRKDC RCN3 SPRY2 TNIP2 UBE2D1	14 interactors: DISC1 HSP90AA1 HSPA1A HSPA8 HUS1 MKNK1 NF1 RAD1 RAD9A SMAD2 SMAD9 SMURF1 TP53 UBE4B
Entrez ID		8569	7266
HPRD ID		09468	07046
Ensembl ID		ENSG00000079277	ENSG00000168259
Uniprot IDs		A8K341 Q9BUB5	Q99615
PDB IDs		2HW6 2Y9Q
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Response To Organic Substance Signaling Cellular Response To Stimulus Cell Communication Cell Surface Receptor Signaling Pathway Cellular Response To Heat Enzyme Linked Receptor Protein Signaling Pathway Toll-like Receptor 3 Signaling Pathway Response To Stimulus Response To Cytokine Defense Response Regulation Of Cellular Response To Heat Viral Process Response To Abiotic Stimulus Innate Immune Response Signal Transduction Cellular Response To Cytokine Stimulus Toll-like Receptor Signaling Pathway Response To Stress Response To Heat Peptidyl-serine Phosphorylation Regulation Of Innate Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Pattern Recognition Receptor Signaling Pathway Immune Response Positive Regulation Of Cellular Metabolic Process Innate Immune Response-activating Signal Transduction Cellular Protein Metabolic Process Regulation Of Translation Immune Response-regulating Signaling Pathway Immune System Process Activation Of Innate Immune Response Cell Cycle Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Cell Death Death TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Protein Phosphorylation MyD88-independent Toll-like Receptor Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Gene Expression Cellular Response To Stress Positive Regulation Of Transferase Activity Positive Regulation Of Gene Expression	Response To Abiotic Stimulus Cellular Response To Stimulus Cellular Response To Ionizing Radiation Response To Radiation Protein Refolding Response To Stimulus Regulation Of Cellular Response To Heat Cellular Response To Radiation Transforming Growth Factor Beta Receptor Signaling Pathway Response To Ionizing Radiation DNA Damage Checkpoint Response To Stress Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Neuroblast Proliferation Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Heat Cell Cycle Checkpoint Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cellular Response To Stress Cellular Response To Growth Factor Stimulus Response To Growth Factor Response To Organic Substance Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Cellular Response To Growth Factor Stimulus Response To Light Stimulus Regulation Of Stem Cell Proliferation Response To Heat Apoptotic Signaling Pathway Brain Development Response To UV Anatomical Structure Development Response To Unfolded Protein Head Development Regulation Of Cellular Process Cellular Macromolecule Catabolic Process Negative Regulation Of Neuroblast Proliferation Mitotic Cell Cycle Checkpoint Negative Regulation Of Cell Cycle Cell Surface Receptor Signaling Pathway Regulation Of Cell Cycle Cellular Metabolic Process Nervous System Development Regulation Of Cell Differentiation Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Stem Cell Proliferation Developmental Process
Tagcloud ?		4ebp1 90kda alphas1 alphas2 casein caseins cows dairy eif4e eif4g export igfbp3 igfbp5 lactating mtorc1 nonpregnant nucleocytoplasmic p70 p85 parenchymal patsearch rps6ka1 s6k ser209 ser2448 ser65 thr197202 thre389 thre412
Tagcloud (Difference) ?		4ebp1 90kda alphas1 alphas2 casein caseins cows dairy eif4e eif4g export igfbp3 igfbp5 lactating mtorc1 nonpregnant nucleocytoplasmic p70 p85 parenchymal patsearch rps6ka1 s6k ser209 ser2448 ser65 thr197202 thre389 thre412
Tagcloud (Intersection) ?