MKNK1 and PHAX

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MKNK1	PHAX
Gene Name		MAP kinase interacting serine/threonine kinase 1	phosphorylated adaptor for RNA export
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Nucleus Nucleoplasm Nucleolus Cytosol Cajal Body Neuronal Cell Body Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	RNA Binding Toxic Substance Binding
	Biological Process	Regulation Of Translational Initiation Protein Phosphorylation Fibroblast Growth Factor Receptor Signaling Pathway Response To Salt Stress Peptidyl-serine Phosphorylation Intracellular Signal Transduction Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Spliceosomal SnRNP Assembly SnRNA Export From Nucleus Gene Expression Protein Transport NcRNA Metabolic Process
Pathways		Signaling by FGFR in disease Spry regulation of FGF signaling Signaling by FGFR Negative regulation of FGFR signaling	snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: APP ATXN3 CREBBP DDAH2 DNAJC7 EIF4E EIF4G1 EIF4G2 EIF4G3 FANCA HGS HIPK2 HSP90AB1 MAPK1 MAPK14 MAPK3 MBP PAK2 PHAX PLA2G4A PRKDC RCN3 SPRY2 TNIP2 UBE2D1	14 interactors: ASPSCR1 GADD45G GRB7 MKNK1 NSFL1C PDPK1 RAD23A RPS6KA1 STK3 TNFSF11 UBXN2A VAV1 XPO1 ZWINT
Entrez ID		8569	51808
HPRD ID		09468	15122
Ensembl ID		ENSG00000079277	ENSG00000164902
Uniprot IDs		A8K341 Q9BUB5	Q9H814
PDB IDs		2HW6 2Y9Q	2XC7
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Response To Organic Substance Signaling Cellular Response To Stimulus Cell Communication Cell Surface Receptor Signaling Pathway Cellular Response To Heat Enzyme Linked Receptor Protein Signaling Pathway Toll-like Receptor 3 Signaling Pathway Response To Stimulus Response To Cytokine Defense Response Regulation Of Cellular Response To Heat Viral Process Response To Abiotic Stimulus Innate Immune Response Signal Transduction Cellular Response To Cytokine Stimulus Toll-like Receptor Signaling Pathway Response To Stress Response To Heat Peptidyl-serine Phosphorylation Regulation Of Innate Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Pattern Recognition Receptor Signaling Pathway Immune Response Positive Regulation Of Cellular Metabolic Process Innate Immune Response-activating Signal Transduction Cellular Protein Metabolic Process Regulation Of Translation Immune Response-regulating Signaling Pathway Immune System Process Activation Of Innate Immune Response Cell Cycle Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Cell Death Death TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Protein Phosphorylation MyD88-independent Toll-like Receptor Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Gene Expression Cellular Response To Stress Positive Regulation Of Transferase Activity Positive Regulation Of Gene Expression	Regulation Of Protein Metabolic Process Response To Stress Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Apoptotic Process Programmed Cell Death Cellular Response To Growth Factor Stimulus Cell Death Death Response To Growth Factor Regulation Of Catalytic Activity Nuclear Envelope Reassembly Positive Regulation Of Cell Activation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Apoptotic Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Epidermal Growth Factor Receptor Signaling Pathway Posttranscriptional Regulation Of Gene Expression Cellular Response To Stimulus Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of JNK Cascade Response To Stimulus Positive Regulation Of Protein Kinase Activity Regulation Of Cell Activation Cellular Response To Stress Positive Regulation Of Kinase Activity Regulation Of Stress-activated MAPK Cascade Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of T Cell Activation Neurotrophin TRK Receptor Signaling Pathway Cell Communication Positive Regulation Of Transferase Activity Positive Regulation Of Homotypic Cell-cell Adhesion Neurotrophin Signaling Pathway Leukocyte Migration Autophagic Vacuole Assembly Positive Regulation Of Cell-cell Adhesion Intracellular Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Proteasomal Protein Catabolic Process Regulation Of Signal Transduction Regulation Of Gene Expression Regulation Of Translation Activation Of Protein Kinase Activity
Tagcloud ?		4ebp1 90kda alphas1 alphas2 casein caseins cows dairy eif4e eif4g export igfbp3 igfbp5 lactating mtorc1 nonpregnant nucleocytoplasmic p70 p85 parenchymal patsearch rps6ka1 s6k ser209 ser2448 ser65 thr197202 thre389 thre412
Tagcloud (Difference) ?		4ebp1 90kda alphas1 alphas2 casein caseins cows dairy eif4e eif4g export igfbp3 igfbp5 lactating mtorc1 nonpregnant nucleocytoplasmic p70 p85 parenchymal patsearch rps6ka1 s6k ser209 ser2448 ser65 thr197202 thre389 thre412
Tagcloud (Intersection) ?