TTBK1 and MAP2

Number of citations of the paper that reports this interaction (PMID 7556643)
7

Data Source:
HPRD (in vitro)

		TTBK1	MAP2
Gene Name		tau tubulin kinase 1	microtubule-associated protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleolus Cytoplasm Microtubule Microtubule Associated Complex Nuclear Periphery Neuronal Cell Body Dendritic Shaft
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding	Dystroglycan Binding Structural Molecule Activity Protein Binding Calmodulin Binding Microtubule Binding
	Biological Process	Regulation Of Cell Shape Peptidyl-serine Phosphorylation Substantia Nigra Development	Microtubule Bundle Formation Axonogenesis Central Nervous System Neuron Development Neuron Projection Development Dendrite Morphogenesis Cellular Response To Organic Substance
Pathways
Drugs			Estramustine Paclitaxel Docetaxel
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CDK5R1 CSN1S1 MAP2 TUBB	24 interactors: ACTB ACTN1 APOE APP CPEB1 DAG1 FYN GRB2 GRIN1 GRIN2D JUNB MARK1 MARK3 MARK4 MYO7A NEDD4L NEFL PAFAH1B1 PLEC PRKACA PRKAR2A SRC TTBK1 TUBA1A
Entrez ID		84630	4133
HPRD ID		11653	01140
Ensembl ID		ENSG00000146216	ENSG00000078018
Uniprot IDs		Q5TCY1	P11137 Q6NYC5
PDB IDs		4BTJ 4BTK 4BTM
Enriched GO Terms of Interacting Partners?		Superior Olivary Nucleus Maturation Pons Maturation Serine Phosphorylation Of STAT3 Protein Serine Phosphorylation Of STAT Protein	Response To Peptide Hormone Response To Peptide Axon Development Response To Organonitrogen Compound Nervous System Development Cellular Component Assembly Neuron Development Response To Wounding Platelet Activation Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Differentiation Neuromuscular Process Cell Projection Organization Movement Of Cell Or Subcellular Component Blood Coagulation Neuron Projection Morphogenesis Hemostasis Generation Of Neurons Response To Hormone Locomotion Neurogenesis Cell Morphogenesis Involved In Differentiation Axonogenesis Cell Morphogenesis Cell Development Response To Abiotic Stimulus Cellular Response To Growth Factor Stimulus Cell Projection Morphogenesis Regulation Of Body Fluid Levels Response To Growth Factor Cell Part Morphogenesis Axon Guidance Chemotaxis Wound Healing Anatomical Structure Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway System Development Response To Organic Substance Transport Cell Surface Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Response To External Stimulus Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Peptide Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Differentiation Cytoskeleton Organization Multicellular Organismal Development
Tagcloud ?		aggregates als amyotrophic attractive devastating drives elegans examining frontal frontotemporal ftld homologs hyperactivity inclusions kinome lobar localize methodology modifiers neurodegeneration neuropathologic phosphorylate proteinopathies refined relocalization reminiscent tdp ttbk2 tubulin	amorphous angiopathy autopsy congophilic cortices filaments frontal granular helical histologically immunolabeled immunolabeling immunolocalized map5 myelin neurofibrillary pallor plaques plastic pyramidal remarkable senile somata spongy sprouting stronger tangles temporal ultrastructurally
Tagcloud (Difference) ?		aggregates als amyotrophic attractive devastating drives elegans examining frontotemporal ftld homologs hyperactivity inclusions kinome lobar localize methodology modifiers neurodegeneration neuropathologic phosphorylate proteinopathies refined relocalization reminiscent tdp ttbk2 tubulin	amorphous angiopathy autopsy congophilic cortices filaments granular helical histologically immunolabeled immunolabeling immunolocalized map5 myelin neurofibrillary pallor plaques plastic pyramidal remarkable senile somata spongy sprouting stronger tangles temporal ultrastructurally
Tagcloud (Intersection) ?		frontal