PIP5K1A and PIP5KL1

Number of citations of the paper that reports this interaction (PMID 14701839)
4

Data Source:
HPRD (in vivo)

		PIP5K1A	PIP5KL1
Gene Name		phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	phosphatidylinositol-4-phosphate 5-kinase-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol MRNA Cleavage And Polyadenylation Specificity Factor Complex Plasma Membrane Focal Adhesion Nuclear Speck Lamellipodium Ruffle Membrane	Cytoplasm Membrane Cell Projection
	Molecular Function	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity Kinase Binding	ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity
	Biological Process	Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phagocytosis Signal Transduction Phospholipid Biosynthetic Process Fibroblast Migration Cell Migration Keratinocyte Differentiation Actin Cytoskeleton Reorganization Activation Of Rac GTPase Activity Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation Focal Adhesion Assembly Cell Chemotaxis Protein Targeting To Plasma Membrane Ruffle Assembly	Phosphatidylinositol Phosphorylation
Pathways		Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: APP ARF1 ARF5 ARF6 BTK CADPS CASP3 PIP5KL1 PLD1 PLD2 TEC	2 interactors: PIP5K1A PIP5K1B
Entrez ID		8394	138429
HPRD ID		04470	15139
Ensembl ID		ENSG00000143398	ENSG00000167103
Uniprot IDs		A6PW57 Q99755	Q5T9C9
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Signaling Cell Communication Glycerophospholipid Metabolic Process Phosphatidylglycerol Biosynthetic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Organelle Localization Response To Oxidative Stress Cellular Copper Ion Homeostasis Signal Transduction Copper Ion Homeostasis Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Phosphate-containing Compound Metabolic Process Glycerophospholipid Biosynthetic Process Establishment Of Vesicle Localization Vesicle Localization Peptidyl-tyrosine Autophosphorylation B Cell Receptor Signaling Pathway Phospholipid Biosynthetic Process Lipid Metabolic Process Regulation Of Immune System Process Immune System Process Defense Response Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Response To Stimulus Neuron Apoptotic Process Cellular Localization Innate Immune Response Establishment Of Organelle Localization Neuron Death Exocytosis Regulation Of B Cell Cytokine Production Immune Response-regulating Cell Surface Receptor Signaling Pathway Neuromuscular Process Controlling Balance Cellular Lipid Metabolic Process Apoptotic Process Programmed Cell Death Organophosphate Metabolic Process Synaptic Growth At Neuromuscular Junction Cellular Response To Molecule Of Fungal Origin Cell Death Death Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Synaptic Vesicle Transport	Phosphatidylinositol Phosphorylation Lipid Phosphorylation Phosphatidylinositol Biosynthetic Process Glycerophospholipid Biosynthetic Process Lipid Modification Phosphatidylinositol Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Lipid Biosynthetic Process Fibroblast Migration Activation Of Rac GTPase Activity Cellular Lipid Metabolic Process Ruffle Assembly Organophosphate Metabolic Process Focal Adhesion Assembly Lipid Metabolic Process Ruffle Organization Activation Of Rho GTPase Activity Protein Targeting To Plasma Membrane Adherens Junction Assembly Cell-substrate Junction Assembly Activation Of Ras GTPase Activity Positive Regulation Of Rac GTPase Activity Actin Cytoskeleton Reorganization Phosphorylation Establishment Of Protein Localization To Plasma Membrane Adherens Junction Organization Keratinocyte Differentiation Small Molecule Metabolic Process Epidermal Cell Differentiation Protein Localization To Plasma Membrane Protein Targeting To Membrane Cell Chemotaxis Cell-matrix Adhesion Phosphate-containing Compound Metabolic Process Ameboidal-type Cell Migration Cell Junction Assembly
Tagcloud ?		1q address akt3 amplified cascades copy cosmic encodes encoding enzymes evident extending iiibeta isozyme issue localize mutational neu numerically oncogenes phosphatidylinositol phosphoinositide pi3kc2b pi4kb quartet resource signalling structurally uncommon
Tagcloud (Difference) ?		1q address akt3 amplified cascades copy cosmic encodes encoding enzymes evident extending iiibeta isozyme issue localize mutational neu numerically oncogenes phosphatidylinositol phosphoinositide pi3kc2b pi4kb quartet resource signalling structurally uncommon
Tagcloud (Intersection) ?