PARP9 and DTX3L

Number of citations of the paper that reports this interaction (PMID 12670957)
19

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		PARP9	DTX3L
Gene Name		poly (ADP-ribose) polymerase family, member 9	deltex 3 like, E3 ubiquitin ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	NAD+ ADP-ribosyltransferase Activity Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Histone Binding
	Biological Process	Double-strand Break Repair Cell Migration Regulation Of Response To Interferon-gamma	Double-strand Break Repair Cellular Response To DNA Damage Stimulus Histone Monoubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)	Major depressive disorder ( 22472876)
Protein-Protein Interactions		1 interactors: DTX3L	19 interactors: DTX1 ITCH PARP9 PHF7 RNF111 SPG21 TRIM9 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2R2 UBE2W
Entrez ID		83666	151636
HPRD ID		10686	16843
Ensembl ID		ENSG00000138496	ENSG00000163840
Uniprot IDs		Q59ER9 Q8IXQ6	Q8TDB6
PDB IDs			3PG6
Enriched GO Terms of Interacting Partners?		Histone Monoubiquitination Histone Ubiquitination Protein Monoubiquitination	Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Macromolecule Catabolic Process Cellular Protein Modification Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Cellular Protein Metabolic Process Catabolic Process Protein Metabolic Process Protein K63-linked Ubiquitination Protein Monoubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Innate Immune Response Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Protein K29-linked Ubiquitination Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Innate Immune Response ISG15-protein Conjugation Regulation Of DNA-templated Transcription In Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Immune System Process Regulation Of Immune Response Toll-like Receptor 4 Signaling Pathway Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Stress Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Positive Regulation Of Immune Response Positive Regulation Of Protein Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Catabolic Process Transcription Initiation From RNA Polymerase II Promoter Mitotic Spindle Assembly Checkpoint
Tagcloud ?		artd artd8 artd9 bal bal1 bbap chemo deltex diphtheria dtx dtx3l du145 hpe il4 immunoprecipitations irf1 lncap macrodomain mono mpca parp14 pc3 proficient repressors ribosyltransferase ribosyltransferases rwpe1 stat1 stat6	artd artd8 artd9 bal bal1 bbap chemo deltex diphtheria du145 hpe il4 immunoprecipitations irf1 lncap macrodomain mono mpca parp14 parp9 pc3 proficient repressors ribosyltransferase ribosyltransferases rwpe1 stat1 stat6
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		artd artd8 artd9 bal bal1 bbap chemo deltex diphtheria dtx dtx3l du145 hpe il4 immunoprecipitations irf1 lncap macrodomain mono mpca parp14 parp9 pc3 proficient repressors ribosyltransferase ribosyltransferases rwpe1 stat1 stat6