LZTR1 and MED7

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		LZTR1	MED7
Gene Name		leucine-zipper-like transcription regulator 1	mediator complex subunit 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Transcription Factor Complex Mitochondrion Mediator Complex Nuclear Membrane
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity	RNA Polymerase II Transcription Cofactor Activity Transcription Coactivator Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Stem Cell Maintenance
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		50 interactors: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 HCLS1 HDAC4 IKBKG KDM2B L3MBTL3 MCM3 MED16 MED7 MYBL2 NR1H3 PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3	22 interactors: CTDP1 ESR1 ESR2 HAUS1 HGS HNF4A IKBKG LZTR1 MED22 MED31 MED8 MED9 PCBD2 PML RBFOX2 RELA RHOXF2 SREBF1 TRIM15 TRIM29 UBE2I ZSCAN1
Entrez ID		8216	9443
HPRD ID		08992	05439
Ensembl ID		ENSG00000099949	ENSG00000155868
Uniprot IDs		Q8N653	O43513 Q6IAZ5
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Regulation Of Gene Expression Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Negative Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process DNA-templated Transcription, Initiation Positive Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Metabolic Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Viral Process Chromatin Organization Viral Process Negative Regulation Of Cellular Metabolic Process Cellular Process Positive Regulation Of Metabolic Process Regulation Of Viral Transcription Chromatin Modification DNA-templated Transcription, Elongation Chromatin Remodeling Positive Regulation Of Viral Transcription	Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Intracellular Estrogen Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process DNA-templated Transcription, Initiation Regulation Of Cellular Process Negative Regulation Of Gene Expression Regulation Of Cell Proliferation Cellular Response To Lipid Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Type I Interferon Production Response To Steroid Hormone Vagina Development Uterus Development Negative Regulation Of Viral Release From Host Cell Steroid Hormone Mediated Signaling Pathway Viral Process Regulation Of Type I Interferon Production Negative Regulation Of Biosynthetic Process Cellular Response To Hormone Stimulus Positive Regulation Of Histone Deacetylation Rhythmic Process Female Genitalia Development Regulation Of Signaling
Tagcloud ?			1h agarose batch bead beads biotinylated centrifugation coactivators comprising concurrently cyclooxygenase detecting enhancer ester evaluating immunoblots incubated pcaf pellet pellets phorbol pulldown room srb7 streptavidin tfii trace transactivators washed
Tagcloud (Difference) ?			1h agarose batch bead beads biotinylated centrifugation coactivators comprising concurrently cyclooxygenase detecting enhancer ester evaluating immunoblots incubated pcaf pellet pellets phorbol pulldown room srb7 streptavidin tfii trace transactivators washed
Tagcloud (Intersection) ?