CAMP and CTSG

Number of citations of the paper that reports this interaction (PMID 11389039)
100

Data Source:
HPRD (in vitro, in vivo)

		CAMP	CTSG
Gene Name		cathelicidin antimicrobial peptide	cathepsin G
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Cell Wall Cytosol Specific Granule Cell Projection Extracellular Vesicular Exosome	Extracellular Region Extracellular Space Nucleus Plasma Membrane Cell Surface Secretory Granule Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity Heparin Binding Peptidase Activity
	Biological Process	Positive Regulation Of Protein Phosphorylation Innate Immune Response In Mucosa Positive Regulation Of Cell Proliferation Antibacterial Humoral Response Defense Response To Bacterium Negative Regulation Of Growth Of Symbiont In Host Negative Regulation Of Growth Of Symbiont On Or Near Host Surface Positive Regulation Of Angiogenesis Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Interaction With Host Killing By Host Of Symbiont Cells Cellular Response To Lipopolysaccharide Cellular Response To Peptidoglycan Cellular Response To Interleukin-1 Cellular Response To Interleukin-6 Cellular Response To Tumor Necrosis Factor Phagosome Maturation	Angiotensin Maturation Proteolysis Immune Response Protein Processing Extracellular Matrix Disassembly Extracellular Matrix Organization Response To Lipopolysaccharide Negative Regulation Of Growth Of Symbiont In Host Cellular Protein Metabolic Process Positive Regulation Of Immune Response Defense Response To Fungus Neutrophil Mediated Killing Of Gram-positive Bacterium
Pathways		Phagosomal maturation (early endosomal stage) Latent infection of Homo sapiens with Mycobacterium tuberculosis	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Peptide hormone metabolism Activation of Matrix Metalloproteinases Metabolism of Angiotensinogen to Angiotensins Degradation of the extracellular matrix
Drugs			Bis-Napthyl Beta-Ketophosphonic Acid 2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CTSG ELANE FPR2 LBP MAPK8 PRTN3	28 interactors: AGT C3 CAMP CASP7 CXCL12 CXCR4 ERBB2IP F2R F2RL1 F2RL2 F5 GP1BA IGFBP3 KNG1 KRT31 LRP1 NOTCH2NL PARP1 PPBP SDC1 SELPLG SERPINA1 SERPINA3 SERPINB13 SERPINB4 SERPIND1 THBS1 VCAM1
Entrez ID		820	1511
HPRD ID		02722	00289
Ensembl ID		ENSG00000164047	ENSG00000100448
Uniprot IDs		J3KNB4 P49913	P08311
PDB IDs		2FBS 2FBU 2FCG 2K6O 2LMF 4EYC	1AU8 1CGH 1KYN 1T32
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Growth Of Symbiont In Host Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Killing By Host Of Symbiont Cells Response To Bacterium Defense Response Positive Regulation Of Immune Response Defense Response To Bacterium Response To Stress Neutrophil Mediated Immunity Response To Other Organism Response To Biotic Stimulus Killing Of Cells Of Other Organism Response To External Stimulus Defense Response To Fungus Negative Regulation Of Growth Response To Lipid Positive Regulation Of Interleukin-8 Production Regulation Of Immune Response Interaction With Symbiont Leukocyte Mediated Cytotoxicity Positive Regulation Of Immune System Process Immune System Process Response To Fungus Regulation Of Chemokine Production Collagen Catabolic Process Inflammatory Response Defense Response To Gram-positive Bacterium Positive Regulation Of Cytokine Biosynthetic Process Immune Response Regulation Of Immune System Process Acute Inflammatory Response Collagen Metabolic Process Toll-like Receptor 4 Signaling Pathway Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Toll-like Receptor Signaling Pathway Regulation Of Cytokine Biosynthetic Process Regulation Of Growth Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Response To UV Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Leukocyte Chemotaxis Involved In Inflammatory Response Lipopolysaccharide Transport Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Regulation Of Chemotaxis Activation Of Innate Immune Response	Cell Activation Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Inflammatory Response Blood Coagulation Hemostasis Wound Healing Response To Wounding Negative Regulation Of Endopeptidase Activity Response To Stress Negative Regulation Of Peptidase Activity Regulation Of Body Fluid Levels Platelet Activation Regulation Of Proteolysis Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Negative Regulation Of Hydrolase Activity Thrombin Receptor Signaling Pathway Regulation Of Protein Processing Response To Stimulus Regulation Of Cellular Protein Metabolic Process Defense Response Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Migration Platelet Degranulation Regulation Of Cell Motility Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Response To External Stimulus Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Transport Regulation Of Catalytic Activity Regulation Of Blood Coagulation Negative Regulation Of Catalytic Activity Cell Surface Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Regulation Of Wound Healing Regulation Of Chemotaxis Response To Cytokine Response To Other Organism Positive Regulation Of Leukocyte Chemotaxis Blood Circulation Response To Biotic Stimulus Secretion By Cell Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Secretion Positive Regulation Of Cell Migration Cellular Chemical Homeostasis Positive Regulation Of Cell Motility
Tagcloud ?		2cl adh admittance antidiuretic ascending augment basolateral basolaterally bilayers channels cl clc conductance ctal cytosolic excised faces gate gated gating k1 ka microperfused mtal pka po rbclc rises thick threefold	aaa aaas aneurysms ang angiotensin aortas aortic cacl2 catg cathepsin converting elastin elastinolytic gelatin immunofluorescent indices indirectly ldlr lesion littermate metalloproteinases mm2 participates periaortic producing protease smcs untested zymogram
Tagcloud (Difference) ?		2cl adh admittance antidiuretic ascending augment basolateral basolaterally bilayers channels cl clc conductance ctal cytosolic excised faces gate gated gating k1 ka microperfused mtal pka po rbclc rises thick threefold	aaa aaas aneurysms ang angiotensin aortas aortic cacl2 catg cathepsin converting elastin elastinolytic gelatin immunofluorescent indices indirectly ldlr lesion littermate metalloproteinases mm2 participates periaortic producing protease smcs untested zymogram
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