CAMP and PRTN3

Number of citations of the paper that reports this interaction (PMID 11389039)
100

Data Source:
HPRD (in vivo, in vitro)

		CAMP	PRTN3
Gene Name		cathelicidin antimicrobial peptide	proteinase 3
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Cell Wall Cytosol Specific Granule Cell Projection Extracellular Vesicular Exosome	Extracellular Space Cytosol Plasma Membrane Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity Serine-type Peptidase Activity Enzyme Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Innate Immune Response In Mucosa Positive Regulation Of Cell Proliferation Antibacterial Humoral Response Defense Response To Bacterium Negative Regulation Of Growth Of Symbiont In Host Negative Regulation Of Growth Of Symbiont On Or Near Host Surface Positive Regulation Of Angiogenesis Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Interaction With Host Killing By Host Of Symbiont Cells Cellular Response To Lipopolysaccharide Cellular Response To Peptidoglycan Cellular Response To Interleukin-1 Cellular Response To Interleukin-6 Cellular Response To Tumor Necrosis Factor Phagosome Maturation	Proteolysis Blood Coagulation Positive Regulation Of Cell Proliferation Collagen Catabolic Process Negative Regulation Of Phagocytosis Mature Conventional Dendritic Cell Differentiation
Pathways		Phagosomal maturation (early endosomal stage) Latent infection of Homo sapiens with Mycobacterium tuberculosis	Common Pathway Formation of Fibrin Clot (Clotting Cascade)
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CTSG ELANE FPR2 LBP MAPK8 PRTN3	13 interactors: CAMP ELN F2R F2RL1 IL1B IL32 ITGB2 RELA SERPINA1 SERPINB1 SERPINB13 SMAD3 TNF
Entrez ID		820	5657
HPRD ID		02722	01512
Ensembl ID		ENSG00000164047	ENSG00000196415
Uniprot IDs		J3KNB4 P49913	P24158
PDB IDs		2FBS 2FBU 2FCG 2K6O 2LMF 4EYC	1FUJ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Growth Of Symbiont In Host Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Killing By Host Of Symbiont Cells Response To Bacterium Defense Response Positive Regulation Of Immune Response Defense Response To Bacterium Response To Stress Neutrophil Mediated Immunity Response To Other Organism Response To Biotic Stimulus Killing Of Cells Of Other Organism Response To External Stimulus Defense Response To Fungus Negative Regulation Of Growth Response To Lipid Positive Regulation Of Interleukin-8 Production Regulation Of Immune Response Interaction With Symbiont Leukocyte Mediated Cytotoxicity Positive Regulation Of Immune System Process Immune System Process Response To Fungus Regulation Of Chemokine Production Collagen Catabolic Process Inflammatory Response Defense Response To Gram-positive Bacterium Positive Regulation Of Cytokine Biosynthetic Process Immune Response Regulation Of Immune System Process Acute Inflammatory Response Collagen Metabolic Process Toll-like Receptor 4 Signaling Pathway Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Toll-like Receptor Signaling Pathway Regulation Of Cytokine Biosynthetic Process Regulation Of Growth Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Response To UV Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Leukocyte Chemotaxis Involved In Inflammatory Response Lipopolysaccharide Transport Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Regulation Of Chemotaxis Activation Of Innate Immune Response	Response To Other Organism Inflammatory Response Response To Biotic Stimulus Positive Regulation Of Interleukin-8 Production Defense Response Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Regulation Of Protein Metabolic Process Positive Regulation Of Cytokine Production Regulation Of Proteolysis Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Positive Regulation Of Interleukin-6 Production Response To External Stimulus Immune Response Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Cellular Protein Metabolic Process Response To Bacterium Regulation Of Cytokine Production Negative Regulation Of Protein Secretion Regulation Of Interleukin-6 Production Positive Regulation Of NF-kappaB Transcription Factor Activity Leukocyte Cell-cell Adhesion Positive Regulation Of Protein Transport Cell Activation Response To Stress Positive Regulation Of Calcidiol 1-monooxygenase Activity Positive Regulation Of Vitamin D Biosynthetic Process Sequestering Of Triglyceride Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Lipopolysaccharide Positive Regulation Of Transcription Factor Import Into Nucleus Cellular Response To Molecule Of Bacterial Origin Negative Regulation Of Secretion By Cell Regulation Of Phosphorylation Negative Regulation Of Secretion Positive Regulation Of Phagocytosis Negative Regulation Of Protein Transport Response To Lipid Negative Regulation Of Cellular Metabolic Process Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Immune Response Regulation Of Chemokine Production Negative Regulation Of Protein Metabolic Process Regulation Of Renin Secretion Into Blood Stream Immune System Process
Tagcloud ?		2cl adh admittance antidiuretic ascending augment basolateral basolaterally bilayers channels cl clc conductance ctal cytosolic excised faces gate gated gating k1 ka microperfused mtal pka po rbclc rises thick threefold	aspartic cathepsin cited2 colonies compromised elastase elementbinding embryogenesis eosinophil fetal gata2 glutamic kit lef lethality lin lineages livers lymphoid manifesting modulator mpo notch1 peroxidase reconstitution sca transactivators uncovers wnt5a
Tagcloud (Difference) ?		2cl adh admittance antidiuretic ascending augment basolateral basolaterally bilayers channels cl clc conductance ctal cytosolic excised faces gate gated gating k1 ka microperfused mtal pka po rbclc rises thick threefold	aspartic cathepsin cited2 colonies compromised elastase elementbinding embryogenesis eosinophil fetal gata2 glutamic kit lef lethality lin lineages livers lymphoid manifesting modulator mpo notch1 peroxidase reconstitution sca transactivators uncovers wnt5a
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