CABLES2 and CDK3

Number of citations of the paper that reports this interaction (PMID 11955625)
2

Data Source:
HPRD (in vivo, in vitro)

		CABLES2	CDK3
Gene Name		Cdk5 and Abl enzyme substrate 2	cyclin-dependent kinase 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function		Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Cell Cycle Cell Division	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Mitotic Nuclear Division Cell Proliferation G0 To G1 Transition Cell Division Regulation Of Cell Cycle
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		4 interactors: ABL1 CDK3 CDK5 TP53	18 interactors: APP CABLES1 CABLES2 CCNA2 CCNC CCNE1 CCNE2 CDC37 CDKN1A CDKN1B CDKN3 E2F1 E2F2 E2F3 KIR3DL1 NEDD4L PPARA RB1
Entrez ID		81928	1018
HPRD ID		12994	00446
Ensembl ID		ENSG00000149679	ENSG00000250506
Uniprot IDs		Q9BTV7	Q00526
PDB IDs			1LFN
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neuron Death Cerebellum Development Metencephalon Development Cell Proliferation Hindbrain Development Regulation Of Cell Cycle Positive Regulation Of Intracellular Transport Regulation Of Neuron Death Cell Cycle Regulation Of Actin Cytoskeleton Reorganization Blood Coagulation Hemostasis Regulation Of Intracellular Transport Negative Regulation Of Cell Cycle Cerebellum Morphogenesis Hindbrain Morphogenesis Neuron Apoptotic Process Growth Positive Regulation Of Neuron Apoptotic Process Neuron Death T Cell Proliferation Regulation Of Body Fluid Levels Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Wound Healing Positive Regulation Of Cell Death Developmental Cell Growth Signal Transduction In Response To DNA Damage Response To Ammonium Ion Regulation Of Establishment Of Protein Localization Mitotic Cell Cycle Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Cell Cycle Arrest Response To Wounding B Cell Differentiation Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Phosphorylation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Autophagy Positive Regulation Of Transport Mitotic Cell Cycle Brain Development Lymphocyte Proliferation Mononuclear Cell Proliferation Membrane Depolarization Regulation Of Protein Localization Head Development Leukocyte Proliferation Transitional One Stage B Cell Differentiation Positive Regulation Of Phosphorylation	Regulation Of Cell Cycle Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Regulation Of Protein Kinase Activity Mitotic Cell Cycle Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Process Cell Cycle Checkpoint Cell Division Regulation Of Phosphorus Metabolic Process Regulation Of Protein Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Cellular Protein Metabolic Process Cell Cycle Process Regulation Of Mitotic Cell Cycle DNA-templated Transcription, Initiation Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Signal Transduction By P53 Class Mediator Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Catalytic Activity Positive Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Lens Fiber Cell Apoptotic Process Notch Signaling Pathway Regulation Of Gene Expression Cell Cycle Arrest Positive Regulation Of Cellular Metabolic Process DNA Damage Checkpoint Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Macromolecule Biosynthetic Process Mitotic Cell Cycle Checkpoint Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Signal Transduction Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Fibroblast Proliferation Negative Regulation Of Cell Cycle Signaling Negative Regulation Of Mitotic Cell Cycle
Tagcloud ?		agilent aifm1 antiproliferative biologically ccnk cdc25b cdca3 cdca8 cnnm3 constituents cytometric dmso emge ginseng ginsenosides hepatocarcinoma hepg2 hspa9 ic50 metabolized mu panax ppt primeview rg3 rh1 saponin saponins uqcrc2	3h adenovirus augmented beta brdu cyclin d2 d3 dedifferentiation exit g0 g1 hypothesized incorporation inducing islets ki67 pancreatic prb quiescence quiescent rat recover regeneration replace staining thymidine transduced tunel
Tagcloud (Difference) ?		agilent aifm1 antiproliferative biologically ccnk cdc25b cdca3 cdca8 cnnm3 constituents cytometric dmso emge ginseng ginsenosides hepatocarcinoma hepg2 hspa9 ic50 metabolized mu panax ppt primeview rg3 rh1 saponin saponins uqcrc2	3h adenovirus augmented beta brdu cyclin d2 d3 dedifferentiation exit g0 g1 hypothesized incorporation inducing islets ki67 pancreatic prb quiescence quiescent rat recover regeneration replace staining thymidine transduced tunel
Tagcloud (Intersection) ?