IFT88 and PRRC2A

Number of citations of the paper that reports this interaction (PMID 14667819)
24

Data Source:
HPRD (two hybrid)

		IFT88	PRRC2A
Gene Name		intraflagellar transport 88	proline-rich coiled-coil 2A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Acrosomal Membrane Centriole Cilium Intraciliary Transport Particle B Motile Primary Cilium Motile Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Apical Part Of Cell Kinocilium Primary Cilium Axonemal Basal Plate Ciliary Tip Ciliary Base	Nucleus Cytoplasm Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Kinesin Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Eye Development Kidney Development Liver Development Epithelial Cell Morphogenesis Organelle Organization Notch Signaling Pathway Smoothened Signaling Pathway Sperm Axoneme Assembly Spermatid Nucleus Elongation Determination Of Left/right Symmetry Protein Localization Epidermis Development Regulation Of Smoothened Signaling Pathway Anterior/posterior Pattern Specification Spinal Cord Dorsal/ventral Patterning Telencephalon Development Pancreas Development Cytoplasmic Microtubule Organization Response To Fluid Shear Stress Epidermal Stem Cell Homeostasis Regulation Of Odontogenesis Of Dentin-containing Tooth Embryonic Digit Morphogenesis Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Fat Cell Differentiation Forebrain Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Cardiac Muscle Cell Differentiation Palate Development Inner Ear Receptor Stereocilium Organization Cilium Morphogenesis Cardiac Septum Morphogenesis Lung Vasculature Development Heart Formation Regulation Of Protein Processing Cochlea Development Regulation Of Cilium Assembly Regulation Of Autophagic Vacuole Assembly
Pathways		Organelle biogenesis and maintenance Hedgehog 'off' state Signaling by Hedgehog Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS		Dental caries ( 23064961) Schizophrenia, bipolar disorder and depression (combined) ( 20713499)	Menopause (age at onset) ( 22267201) Schizophrenia ( 23894747)
Protein-Protein Interactions		2 interactors: PRRC2A RPGR	27 interactors: ATN1 ATXN1 C1QBP CCR10 CPSF1 DDX20 EIF3E EWSR1 FGA GANAB GORASP2 GRB2 HNRNPA1 HNRNPM IFT88 IMMT JUN MAD2L2 MAN2C1 P4HA2 PRMT2 PSMA3 QARS RBFOX1 RERE SSR3 UBAP2L
Entrez ID		8100	7916
HPRD ID		09000	00807
Ensembl ID		ENSG00000032742	ENSG00000204469
Uniprot IDs		B3KX42 F5H6C2 Q13099	P48634
PDB IDs
Enriched GO Terms of Interacting Partners?		Intraciliary Transport Eye Photoreceptor Cell Development Photoreceptor Cell Development Eye Photoreceptor Cell Differentiation	Gene Expression MRNA Metabolic Process RNA Splicing RNA Metabolic Process RNA Processing MRNA Processing Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleocytoplasmic Transport Nuclear Transport Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Cytoplasmic Transport MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Signal Transduction In Response To DNA Damage Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Nuclear Export Nuclear Import Negative Regulation Of Protein Metabolic Process Positive Regulation Of Substrate Adhesion-dependent Cell Spreading RNA Transport Negative Regulation Of Mitotic Cell Cycle Phase Transition RNA Localization Regulation Of Substrate Adhesion-dependent Cell Spreading Cellular Metabolic Process Ribonucleoprotein Complex Assembly Negative Regulation Of Signal Transduction Glutaminyl-tRNA Aminoacylation Negative Regulation Of Blood Coagulation, Common Pathway Blood Coagulation, Common Pathway Cellular Response To Potassium Ion Starvation Negative Regulation Of DNA Binding Negative Regulation Of Signaling Regulation Of Cell Morphogenesis Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle
Tagcloud ?		ag1478 amiloride cilia collecting duct efflux egf erbb1 erbb3 erbb4 exchangers exerts hypomorph isobutyl mek mia mitogenic mrnas nhe nhes orpk pd98059 pkd polycystic pronounced proton severely stunted tg737
Tagcloud (Difference) ?		ag1478 amiloride cilia collecting duct efflux egf erbb1 erbb3 erbb4 exchangers exerts hypomorph isobutyl mek mia mitogenic mrnas nhe nhes orpk pd98059 pkd polycystic pronounced proton severely stunted tg737
Tagcloud (Intersection) ?