KAT6A and ATN1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT6A	ATN1
Gene Name		K(lysine) acetyltransferase 6A	atrophin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm Nucleolus Golgi Apparatus PML Body MOZ/MORF Histone Acetyltransferase Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Acetyltransferase Activity	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Toxin Receptor Binding
	Biological Process	Heart Morphogenesis DNA Packaging Chromatin Organization Nucleosome Assembly Transcription, DNA-templated Protein Acetylation Histone Acetylation Myeloid Cell Differentiation Somatic Stem Cell Maintenance Embryonic Hemopoiesis Aorta Morphogenesis Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Histone H3 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Face Morphogenesis Cellular Senescence	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Central Nervous System Development Toxin Metabolic Process Cell Migration Maintenance Of Cell Polarity Neuron Apoptotic Process
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: AKT1 ATN1 ATXN1 CREBBP H3F3C HIST1H3A HIST1H4A HIST1H4I HIST2H3C HIST3H3 HIST4H4 MAFK PML RERE RUNX1 SPI1 TP53 UBE2U	93 interactors: AES AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPO STXBP4 SYVN1 TEP1 TLE1 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8
Entrez ID		7994	1822
HPRD ID		03244	06311
Ensembl ID		ENSG00000083168	ENSG00000111676
Uniprot IDs		A5PKX7 Q92794	P54259 Q86V38
PDB IDs		1M36 2LN0 2OZU 2RC4 3V43
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Chromatin Silencing At RDNA Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Chromatin Silencing Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Replication-dependent Nucleosome Assembly Gene Expression Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Chromosome Organization Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Methylation Negative Regulation Of Cellular Metabolic Process Histone H4-K20 Demethylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process DNA Modification Regulation Of RNA Metabolic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Megakaryocyte Differentiation Gene Silencing Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Chromatin Assembly Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Chromatin Assembly Or Disassembly Chromatin Modification Regulation Of Myeloid Cell Differentiation DNA Packaging Organelle Organization Histone Modification Telomere Maintenance DNA Metabolic Process Regulation Of Megakaryocyte Differentiation Negative Regulation Of Myeloid Cell Differentiation Negative Regulation Of Cell Differentiation Regulation Of Cell Differentiation Nucleocytoplasmic Transport CENP-A Containing Nucleosome Assembly Nuclear Transport DNA Conformation Change Protein Import Into Nucleus	Regulation Of Cellular Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Multicellular Organismal Development Regulation Of Nitrogen Compound Metabolic Process Developmental Process Regulation Of Gene Expression Signaling Regulation Of Signaling Signal Transduction Nervous System Development Anatomical Structure Development Cell Communication Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of RNA Metabolic Process Cellular Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Extracellular Matrix Organization Extracellular Structure Organization Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteolysis Regulation Of RNA Biosynthetic Process System Development Response To Stimulus Cell Death Death Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Morphogenesis Modification-dependent Protein Catabolic Process Protein Catabolic Process Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Biosynthetic Process Protein Ubiquitination Axon Development
Tagcloud ?		acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes localizes lymphoma maintain maintaining maintains malignancy meis1 menin mll1 moz myst3 ncoa3 overlap progenitor progenitors proliferative tale tif2 translocations	atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine
Tagcloud (Difference) ?		acetyltransferase aggressive characteristically emu fusing haploinsufficient hence homeobox hox includes localizes lymphoma maintain maintaining maintains malignancy meis1 menin mll1 moz myst3 ncoa3 overlap progenitors proliferative tale tif2 translocations	atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature repression rescued seq surprisingly tranylcypromine
Tagcloud (Intersection) ?		progenitor