ATN1 and RUNX1T1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATN1	RUNX1T1
Gene Name		atrophin 1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm Mitochondrion Nuclear Matrix
	Molecular Function	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Toxin Receptor Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Central Nervous System Development Toxin Metabolic Process Cell Migration Maintenance Of Cell Polarity Neuron Apoptotic Process	Generation Of Precursor Metabolites And Energy Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		93 interactors: AES AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPO STXBP4 SYVN1 TEP1 TLE1 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8	53 interactors: ABI3 ATN1 BCL6 BRCA1 C19orf57 CBFA2T3 CCDC36 CEP170P1 CPSF7 CREB3L1 DNMT1 EFHC2 EPS8 ETS1 GFI1 GSE1 HDAC1 HDAC3 HDAC8 HOMER3 HSP90AA1 ID1 ID3 KPNA1 KPNB1 LPXN LZTS2 MEOX2 MID2 NCOR1 NCOR2 NECAB2 NEUROG1 PCBD2 PRDM14 PRKAR2A SIN3A SPEN SPERT SPRY2 STX11 TAF9B TAL2 TCF12 TCF3 TCF4 TRIM42 UBQLN4 VDR WBP11 ZBTB16 ZMYM4 ZNF652
Entrez ID		1822	862
HPRD ID		06311	00590
Ensembl ID		ENSG00000111676	ENSG00000079102
Uniprot IDs		P54259 Q86V38	B2R6I9 Q06455
PDB IDs			1WQ6 2DJ8 2H7B 2KNH 2KYG 2OD1 2ODD 2PP4 4JOL
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Multicellular Organismal Development Regulation Of Nitrogen Compound Metabolic Process Developmental Process Regulation Of Gene Expression Signaling Regulation Of Signaling Signal Transduction Nervous System Development Anatomical Structure Development Cell Communication Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of RNA Metabolic Process Cellular Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Extracellular Matrix Organization Extracellular Structure Organization Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteolysis Regulation Of RNA Biosynthetic Process System Development Response To Stimulus Cell Death Death Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Morphogenesis Modification-dependent Protein Catabolic Process Protein Catabolic Process Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Biosynthetic Process Protein Ubiquitination Axon Development	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Heterocycle Metabolic Process Negative Regulation Of Gene Expression Cellular Aromatic Compound Metabolic Process Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cellular Process Multicellular Organismal Development Positive Regulation Of Macromolecule Biosynthetic Process Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Embryo Development Cellular Metabolic Process Organ Development Developmental Process Anatomical Structure Development System Development Transcription Initiation From RNA Polymerase II Promoter Regulation Of Cell Differentiation Cellular Response To Organic Substance Rhythmic Process Organelle Organization Regulation Of Apoptotic Process
Tagcloud ?		atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine	accumulated aml aml201 cbfb cebpa chimeric clarify comprehensively cooperative cytogenetically cytogenetics dnmt3a exclusive flt3 impacts japan kit leukemianet mll myh11 npm1 precise ptd recurrently registered sole stratified translocations
Tagcloud (Difference) ?		atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly premature progenitor repression rescued seq surprisingly tranylcypromine	accumulated aml aml201 cbfb cebpa chimeric clarify comprehensively cooperative cytogenetically cytogenetics dnmt3a exclusive flt3 impacts japan kit leukemianet mll myh11 npm1 ptd recurrently registered sole stratified translocations
Tagcloud (Intersection) ?		precise