TM7SF2 and RAP2A

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		TM7SF2	RAP2A
Gene Name		transmembrane 7 superfamily member 2	RAP2A, member of RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Receptor Complex	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Delta14-sterol Reductase Activity	GTPase Activity Protein Binding GTP Binding
	Biological Process	Cholesterol Biosynthetic Process Small Molecule Metabolic Process Oxidation-reduction Process	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) Cholesterol biosynthesis Metabolism of lipids and lipoproteins Activation of gene expression by SREBF (SREBP)
Drugs			Guanosine-5\'-Triphosphate Guanosine-5\'-Diphosphate
Diseases
GWAS
Protein-Protein Interactions		1 interactors: RAP2A	32 interactors: ACVR1 ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 MLLT4 NEDD4 PLG RAF1 RALA RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK
Entrez ID		7108	5911
HPRD ID		04564	01547
Ensembl ID		ENSG00000149809
Uniprot IDs		O76062	P10114
PDB IDs			1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?		Rap Protein Signal Transduction Microvillus Assembly Microvillus Organization Positive Regulation Of Protein Autophosphorylation Regulation Of Protein Autophosphorylation Cellular Response To Drug Actin Cytoskeleton Reorganization Regulation Of Dendrite Morphogenesis	Intracellular Signal Transduction Response To Stimulus Regulation Of Signaling Regulation Of Catalytic Activity Cell Communication Signal Transduction Cellular Response To Stimulus Positive Regulation Of Metabolic Process Positive Regulation Of Rap GTPase Activity Signaling Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Rap GTPase Activity Positive Regulation Of Catalytic Activity Regulation Of Rap Protein Signal Transduction Signal Transduction By Phosphorylation Regulation Of Metabolic Process Small GTPase Mediated Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Ras Protein Signal Transduction Regulation Of GTPase Activity Wound Healing Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Ras Protein Signal Transduction Regulation Of Dendrite Morphogenesis Response To Wounding Regulation Of Cell Projection Organization Positive Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Platelet Activation Regulation Of Ras GTPase Activity Cellular Response To Growth Factor Stimulus Response To Organic Substance Regulation Of Cellular Process Response To Growth Factor Regulation Of Dendrite Development Cardiovascular System Development Cell Surface Receptor Signaling Pathway Positive Regulation Of Ras GTPase Activity Regulation Of Cell Differentiation Negative Regulation Of Cell Proliferation Cell Activation Regulation Of Cellular Localization Cell Differentiation Blood Vessel Development Response To Stress Vasculature Development Regulation Of Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Activation Of MAPKK Activity
Tagcloud ?			cleave competitors degrades diaminopimelic effectors endopeptidase endopeptidases exploiting extrude heteromeric marcescens meso muropeptides neutralization neutralize orthologues pentapeptides promiscuity rap1a raps serratia ssp1 ssp2 steric tetrapenta tetrapeptides tetratetra tetratetrapeptides tripeptides
Tagcloud (Difference) ?			cleave competitors degrades diaminopimelic effectors endopeptidase endopeptidases exploiting extrude heteromeric marcescens meso muropeptides neutralization neutralize orthologues pentapeptides promiscuity rap1a raps serratia ssp1 ssp2 steric tetrapenta tetrapeptides tetratetra tetratetrapeptides tripeptides
Tagcloud (Intersection) ?