TJP1 and YBX3

Number of citations of the paper that reports this interaction (PMID 16508013)
43

Data Source:
BioGRID (pull down)

		TJP1	YBX3
Gene Name		tight junction protein 1	Y box binding protein 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Adherens Junction Gap Junction Tight Junction Intercalated Disc Basolateral Plasma Membrane Apical Plasma Membrane Apicolateral Plasma Membrane Cell Junction Apical Junction Complex Apical Part Of Cell Intercellular Canaliculus	Nucleus Cytoplasm Polysome Tight Junction Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Calmodulin Binding Protein C-terminus Binding Protein Domain Specific Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Double-stranded DNA Binding Single-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity MRNA 3'-UTR Binding Rho GTPase Binding Poly(A) RNA Binding
	Biological Process	Blastocyst Formation Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell-cell Junction Assembly Sensory Perception Of Sound Response To Lipopolysaccharide Hippo Signaling Response To Drug Negative Regulation Of Vascular Permeability Response To Ethanol Membrane Organization Response To Magnetism Cellular Response To Glucose Stimulus Establishment Of Endothelial Intestinal Barrier Cell-cell Signaling Involved In Cell-cell Junction Organization	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Transcription, DNA-templated Spermatogenesis Male Gonad Development Response To Cold Fertilization Positive Regulation Of Organ Growth Negative Regulation Of Skeletal Muscle Tissue Development Negative Regulation Of Necroptotic Process 3'-UTR-mediated MRNA Stabilization Cellular Response To Tumor Necrosis Factor Cellular Hyperosmotic Response Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Positive Regulation Of Cytoplasmic Translation
Pathways		Apoptotic cleavage of cell adhesion proteins c-src mediated regulation of Cx43 function and closure of gap junctions Apoptotic cleavage of cellular proteins Signaling by Hippo Gap junction trafficking and regulation Programmed Cell Death Apoptotic execution phase Regulation of gap junction activity
Drugs
Diseases
GWAS		Corneal structure ( 23291589) Response to antipsychotic treatment ( 23241943)
Protein-Protein Interactions		38 interactors: ACTA1 ACTN4 ARVCF CGN CLDN1 CLDN16 CLDN2 CLDN3 CLDN4 CLDN5 CLDN6 CLDN7 CLDN8 CNKSR2 CTNNA1 CTTN EGFR F11R GJA1 GJA3 GJA8 GJB3 GJC1 GJD3 GRIN1 GRIN2D HSP90AA1 JAM2 JAM3 KHDRBS1 KIRREL MLLT4 PTPN14 TJP2 TJP3 TRPC4 UBN1 YBX3	8 interactors: GSK3B IL7R MAPK1 NFYB PCBP2 RALA TJP1 VEGFA
Entrez ID		7082	8531
HPRD ID		03002	10347
Ensembl ID		ENSG00000104067	ENSG00000060138
Uniprot IDs		G3V1L9 Q07157 Q6MZU1	P16989
PDB IDs		2H2B 2H2C 2H3M 2JWE 2KXR 2KXS 2RCZ 3CYY 3LH5 3SHU 3SHW 3TSV 3TSW 3TSZ
Enriched GO Terms of Interacting Partners?		Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell-cell Junction Organization Cell Adhesion Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Cell Junction Assembly Cell-cell Junction Assembly Gap Junction Assembly Cell Development Establishment Of Endothelial Intestinal Barrier Anatomical Structure Development Cellular Component Assembly Developmental Process Epithelial Cell Development Apical Junction Assembly Establishment Of Endothelial Barrier Endothelium Development Neuron Projection Development Regulation Of Body Fluid Levels Response To Abiotic Stimulus Regulation Of Actin Filament-based Process Anatomical Structure Morphogenesis Tight Junction Assembly Transmembrane Transport Endothelial Cell Development Response To Organic Substance System Development Movement Of Cell Or Subcellular Component Neuron Development Cell Differentiation Atrial Cardiac Muscle Cell Action Potential Atrial Cardiac Muscle Cell To AV Node Cell Communication Multicellular Organismal Development Locomotion Cell Communication Single Organismal Cell-cell Adhesion Epithelial Cell Differentiation Cell Morphogenesis Axon Development Endothelial Cell Differentiation Neuron Differentiation Cell-cell Signaling Involved In Cardiac Conduction Cell Projection Organization Positive Regulation Of Rap GTPase Activity Neurological System Process Establishment Of Skin Barrier Adherens Junction Organization Skin Development Neuron Projection Morphogenesis Cell-cell Signaling	Response To External Stimulus Cellular Response To Organic Substance Regulation Of Cell Size Positive Regulation Of Peptidyl-threonine Phosphorylation Cellular Response To Growth Factor Stimulus Regulation Of Immune System Process Chemotaxis Response To Growth Factor Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Response To Heat Regulation Of Vascular Permeability Neurotrophin Signaling Pathway Positive Regulation Of Gene Expression Response To Biotic Stimulus Positive Regulation Of Axon Extension Positive Regulation Of Cell Projection Organization Regulation Of MAP Kinase Activity Positive Regulation Of Cellular Component Biogenesis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Component Size Positive Regulation Of Cell-matrix Adhesion Apoptotic Process Positive Regulation Of Cell Adhesion Programmed Cell Death Regulation Of Vesicle-mediated Transport Cellular Response To Heat Regulation Of Cellular Localization Axon Guidance Cell Death Death Cell Morphogenesis Regulation Of Axon Extension Regulation Of Cellular Amino Acid Metabolic Process Response To Abiotic Stimulus Immune System Process Positive Regulation Of Axonogenesis Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Kinase D Signaling Cell-cell Signaling Involved In Cell-cell Junction Organization Basophil Chemotaxis Regulation Of Cell Projection Organization Locomotion Anatomical Structure Morphogenesis Regulation Of Cellular Ketone Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway In Utero Embryonic Development Immune Response Regulation Of Peptidyl-serine Phosphorylation
Tagcloud ?		abp androgen ar blots clonal clu constitutes fshr hampering immortalized immunocytochemistry inhbb investigations loose mediators microarrays posttranslational responsiveness rhox5 sc sertoli sox9 spermatogenesis spinlw1 st38c stabilization testosterone undergoes wt1	absent alleles aml atlas australasian bank box conjunction enrichment epigenetic frequently hnrnpr hypermethylation leukemic marks matr3 promoter sf3a1 sf3b1 silence silico somatic splicing srsf2 suppressing u2af1 u937 zfr zrsr2
Tagcloud (Difference) ?		abp androgen ar blots clonal clu constitutes fshr hampering immortalized immunocytochemistry inhbb investigations loose mediators microarrays posttranslational responsiveness rhox5 sc sertoli sox9 spermatogenesis spinlw1 st38c stabilization testosterone undergoes wt1	absent alleles aml atlas australasian bank box conjunction enrichment epigenetic frequently hnrnpr hypermethylation leukemic marks matr3 promoter sf3a1 sf3b1 silence silico somatic splicing srsf2 suppressing u2af1 u937 zfr zrsr2
Tagcloud (Intersection) ?