TJP1 and TJP3

Number of citations of the paper that reports this interaction (PMID 9531559)
94

Data Source:
HPRD (in vitro)

		TJP1	TJP3
Gene Name		tight junction protein 1	tight junction protein 3
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Adherens Junction Gap Junction Tight Junction Intercalated Disc Basolateral Plasma Membrane Apical Plasma Membrane Apicolateral Plasma Membrane Cell Junction Apical Junction Complex Apical Part Of Cell Intercellular Canaliculus	Nucleus Nucleoplasm Tight Junction Apical Plasma Membrane Cell Junction
	Molecular Function	Protein Binding Calmodulin Binding Protein C-terminus Binding Protein Domain Specific Binding	Protein Binding
	Biological Process	Blastocyst Formation Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell-cell Junction Assembly Sensory Perception Of Sound Response To Lipopolysaccharide Hippo Signaling Response To Drug Negative Regulation Of Vascular Permeability Response To Ethanol Membrane Organization Response To Magnetism Cellular Response To Glucose Stimulus Establishment Of Endothelial Intestinal Barrier Cell-cell Signaling Involved In Cell-cell Junction Organization	Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Apoptotic cleavage of cell adhesion proteins c-src mediated regulation of Cx43 function and closure of gap junctions Apoptotic cleavage of cellular proteins Signaling by Hippo Gap junction trafficking and regulation Programmed Cell Death Apoptotic execution phase Regulation of gap junction activity
Drugs
Diseases
GWAS		Corneal structure ( 23291589) Response to antipsychotic treatment ( 23241943)
Protein-Protein Interactions		38 interactors: ACTA1 ACTN4 ARVCF CGN CLDN1 CLDN16 CLDN2 CLDN3 CLDN4 CLDN5 CLDN6 CLDN7 CLDN8 CNKSR2 CTNNA1 CTTN EGFR F11R GJA1 GJA3 GJA8 GJB3 GJC1 GJD3 GRIN1 GRIN2D HSP90AA1 JAM2 JAM3 KHDRBS1 KIRREL MLLT4 PTPN14 TJP2 TJP3 TRPC4 UBN1 YBX3	5 interactors: CLDN1 FASLG GJC1 INADL TJP1
Entrez ID		7082	27134
HPRD ID		03002	18194
Ensembl ID		ENSG00000104067	ENSG00000105289
Uniprot IDs		G3V1L9 Q07157 Q6MZU1	B3KR73 F5H2X0 O95049
PDB IDs		2H2B 2H2C 2H3M 2JWE 2KXR 2KXS 2RCZ 3CYY 3LH5 3SHU 3SHW 3TSV 3TSW 3TSZ	3KFV
Enriched GO Terms of Interacting Partners?		Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell-cell Junction Organization Cell Adhesion Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Cell Junction Assembly Cell-cell Junction Assembly Gap Junction Assembly Cell Development Establishment Of Endothelial Intestinal Barrier Anatomical Structure Development Cellular Component Assembly Developmental Process Epithelial Cell Development Apical Junction Assembly Establishment Of Endothelial Barrier Endothelium Development Neuron Projection Development Regulation Of Body Fluid Levels Response To Abiotic Stimulus Regulation Of Actin Filament-based Process Anatomical Structure Morphogenesis Tight Junction Assembly Transmembrane Transport Endothelial Cell Development Response To Organic Substance System Development Movement Of Cell Or Subcellular Component Neuron Development Cell Differentiation Atrial Cardiac Muscle Cell Action Potential Atrial Cardiac Muscle Cell To AV Node Cell Communication Multicellular Organismal Development Locomotion Cell Communication Single Organismal Cell-cell Adhesion Epithelial Cell Differentiation Cell Morphogenesis Axon Development Endothelial Cell Differentiation Neuron Differentiation Cell-cell Signaling Involved In Cardiac Conduction Cell Projection Organization Positive Regulation Of Rap GTPase Activity Neurological System Process Establishment Of Skin Barrier Adherens Junction Organization Skin Development Neuron Projection Morphogenesis Cell-cell Signaling	Cell-cell Junction Organization Cell-cell Junction Assembly Cell Junction Assembly Cell-cell Signaling Involved In Cell-cell Junction Organization Response To Glucose Chemical Homeostasis Cell-cell Signaling Endosomal Lumen Acidification Response To Carbohydrate Response To Magnetism Retinal Cell Programmed Cell Death Necroptotic Signaling Pathway Establishment Of Endothelial Intestinal Barrier Response To Lipopolysaccharide Cellular Chloride Ion Homeostasis Inflammatory Cell Apoptotic Process Homeostatic Process Atrial Cardiac Muscle Cell To AV Node Cell Communication Atrial Cardiac Muscle Cell Action Potential Chloride Ion Homeostasis Response To Molecule Of Bacterial Origin Positive Regulation Of Endothelial Cell Apoptotic Process Negative Regulation Of Vascular Permeability Cell-cell Signaling Involved In Cardiac Conduction Establishment Of Skin Barrier T Cell Apoptotic Process Cell Development Response To Bacterium Regulation Of Water Loss Via Skin Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Intracellular PH Reduction Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cellular Component Assembly PH Reduction Cellular Chemical Homeostasis Gap Junction Assembly Positive Regulation Of ERBB Signaling Pathway Establishment Of Endothelial Barrier Cardiac Muscle Cell Action Potential Involved In Contraction Hippo Signaling Endosome Organization Necroptotic Process Regulation Of Vascular Permeability Multicellular Organismal Development Regulation Of Endothelial Cell Apoptotic Process Anatomical Structure Development Cardiac Muscle Cell Action Potential Cellular Homeostasis Blastocyst Formation Developmental Programmed Cell Death
Tagcloud ?		abp androgen ar blots clonal clu constitutes fshr hampering immortalized immunocytochemistry inhbb investigations loose mediators microarrays posttranslational responsiveness rhox5 sc sertoli sox9 spermatogenesis spinlw1 st38c stabilization testosterone undergoes wt1	adherens atp1a1 atp1b1 bbs1 biogenesis cdh1 cilium cldn2 delineation dynamic fasn foxo1 glycolytic hif1a invaluable junction maturation matured metabolomic monolayer nutrient profound proliferating tight transam transcriptomic tubule uncovered utilizing
Tagcloud (Difference) ?		abp androgen ar blots clonal clu constitutes fshr hampering immortalized immunocytochemistry inhbb investigations loose mediators microarrays posttranslational responsiveness rhox5 sc sertoli sox9 spermatogenesis spinlw1 st38c stabilization testosterone undergoes wt1	adherens atp1a1 atp1b1 bbs1 biogenesis cdh1 cilium cldn2 delineation dynamic fasn foxo1 glycolytic hif1a invaluable junction maturation matured metabolomic monolayer nutrient profound proliferating tight transam transcriptomic tubule uncovered utilizing
Tagcloud (Intersection) ?