TG and ASGR1

Number of citations of the paper that reports this interaction (PMID 12477859)
21

Data Source:
HPRD (in vivo)

		TG	ASGR1
Gene Name		thyroglobulin	asialoglycoprotein receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Integral Component Of Plasma Membrane
	Molecular Function	Hormone Activity Carboxylic Ester Hydrolase Activity	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Signal Transduction Iodide Transport Thyroid Gland Development Regulation Of Myelination Thyroid Hormone Metabolic Process Hormone Biosynthetic Process	Receptor-mediated Endocytosis Cellular Response To Extracellular Stimulus
Pathways
Drugs
Diseases
GWAS		Graves' disease ( 23612905) Temperament ( 22832960)	Liver enzyme levels (alkaline phosphatase) ( 22001757)
Protein-Protein Interactions		9 interactors: APCS ASGR1 CANX CTSD CTSL HSP90B1 HSPA5 LRP2 P4HB	12 interactors: APP ASGR2 CERS2 CLEC4G DHFR HIVEP1 HSP90AA1 HSP90B1 NLK RBBP6 TG VKORC1
Entrez ID		7038	432
HPRD ID		01782	00151
Ensembl ID		ENSG00000042832	ENSG00000141505
Uniprot IDs		P01266	P07306 Q6FGQ5
PDB IDs			1DV8
Enriched GO Terms of Interacting Partners?		Protein Folding Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Receptor-mediated Endocytosis Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Response To Endoplasmic Reticulum Stress Endocytosis Protein Metabolic Process Antigen Processing And Presentation Of Peptide Antigen Vesicle-mediated Transport ER-associated Ubiquitin-dependent Protein Catabolic Process Proteolysis Antigen Processing And Presentation Cellular Protein Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Collagen Catabolic Process Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Protein Folding In Endoplasmic Reticulum Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Extracellular Matrix Disassembly Immune System Process Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Toll-like Receptor Signaling Pathway Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Actin Rod Assembly Cerebellum Structural Organization Negative Regulation Of Exo-alpha-sialidase Activity Macrophage Apoptotic Process Cellular Response To Topologically Incorrect Protein Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Response To Unfolded Protein Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Protein Catabolic Process Sequestering Of Calcium Ion Positive Regulation Of Innate Immune Response Negative Regulation Of Monocyte Differentiation Cellular Response To Extracellular Stimulus Innate Immune Response Myeloid Cell Apoptotic Process Catabolic Process	Nitric Oxide Metabolic Process Reactive Nitrogen Species Metabolic Process Cellular Metabolic Process Regulation Of Nitric-oxide Synthase Activity Endocytosis Receptor-mediated Endocytosis Regulation Of Oxidoreductase Activity Actin Rod Assembly Synaptic Growth At Neuromuscular Junction Reactive Oxygen Species Metabolic Process Vitamin Metabolic Process Collateral Sprouting In Absence Of Injury Response To Unfolded Protein Protein Import Into Mitochondrial Outer Membrane Serine Phosphorylation Of STAT3 Protein Sequestering Of Calcium Ion Collateral Sprouting Axon Midline Choice Point Recognition Serine Phosphorylation Of STAT Protein Small Molecule Metabolic Process Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Iodide Transport Axon Choice Point Recognition Vitamin K Metabolic Process Vesicle-mediated Transport
Tagcloud ?		amplify aspiration checked cytological cytology deiodinase di diagnostically dii dilutions fine fnab fnabs ftc ie iodide iodothyronine isolation mentioned needle nis obtaining preparing rendered routinely smears suspicious symporter thyroglobulin thyroid
Tagcloud (Difference) ?		amplify aspiration checked cytological cytology deiodinase di diagnostically dii dilutions fine fnab fnabs ftc ie iodide iodothyronine isolation mentioned needle nis obtaining preparing rendered routinely smears suspicious symporter thyroglobulin thyroid
Tagcloud (Intersection) ?