CNTN2 and TAX1BP3

Number of citations of the paper that reports this interaction (PMID 19609363)
23

Data Source:
BioGRID (two hybrid)

		CNTN2	TAX1BP3
Gene Name		contactin 2 (axonal)	Tax1 (human T-cell leukemia virus type I) binding protein 3
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Anchored Component Of Membrane Node Of Ranvier Neuronal Cell Body Myelin Sheath Juxtaparanode Region Of Axon Synapse	Nucleus Cytoplasm Plasma Membrane Actin Cytoskeleton Extracellular Vesicular Exosome
	Molecular Function	Glycoprotein Binding Carbohydrate Binding Identical Protein Binding Protein Self-association	Protein Binding Beta-catenin Binding Protein C-terminus Binding
	Biological Process	Microtubule Cytoskeleton Organization Cell Adhesion Axon Guidance Axonal Fasciculation Learning Adult Walking Behavior Positive Regulation Of Protein Processing Cerebral Cortex GABAergic Interneuron Migration Central Nervous System Myelination Regulation Of Axon Diameter Receptor Internalization Cellular Protein Localization Clustering Of Voltage-gated Potassium Channels Negative Regulation Of Neuron Differentiation Regulation Of Neuronal Synaptic Plasticity Regulation Of Astrocyte Differentiation Positive Regulation Of Adenosine Receptor Signaling Pathway Establishment Of Protein Localization To Juxtaparanode Region Of Axon Presynaptic Membrane Organization	Rho Protein Signal Transduction Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Activation Of Cdc42 GTPase Activity Negative Regulation Of Protein Localization To Cell Surface
Pathways		NCAM1 interactions Axon guidance L1CAM interactions NrCAM interactions NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: CNTN1 CNTNAP2 CREBBP EGFR EP300 HDAC1 KAT2B L1CAM NCAN NFYB NRCAM SRF TAX1BP1 TAX1BP3 TUBG1 VAC14	14 interactors: ARNT2 CDK5RAP3 CNTN2 CTNNB1 DTX1 GATA1 GLS GLS2 PLK4 RNF183 RTKN STAU1 TCEA2 TRIM29
Entrez ID		6900	30851
HPRD ID		01826	18160
Ensembl ID		ENSG00000184144	ENSG00000213977
Uniprot IDs		A1L3A3 Q02246	O14907
PDB IDs		2OM5	2KG2 2L4S 2L4T 2VZ5 3GJ9 3SFJ 4E3B
Enriched GO Terms of Interacting Partners?		N-terminal Peptidyl-lysine Acetylation Notch Signaling Pathway N-terminal Protein Amino Acid Acetylation Neuron Projection Development N-terminal Protein Amino Acid Modification Viral Process Rhythmic Process Neuron Development Positive Regulation Of Gene Expression Neuron Differentiation Axon Guidance Cell Morphogenesis Involved In Differentiation Cell Projection Organization Cell Adhesion Anatomical Structure Morphogenesis Cell Development Positive Regulation Of Transcription, DNA-templated Axonogenesis Central Nervous System Development Cell Communication Axon Development Positive Regulation Of Macromolecule Biosynthetic Process Neuronal Ion Channel Clustering Cell Morphogenesis Involved In Neuron Differentiation Generation Of Neurons Chemotaxis Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Hypoxia Positive Regulation Of Cellular Biosynthetic Process Cell Morphogenesis Nervous System Development Neuron Projection Morphogenesis Regulation Of Type I Interferon Production Neurogenesis Histone Acetylation Eyelid Development In Camera-type Eye Embryo Development Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Regulation Of Androgen Receptor Signaling Pathway Protein Acetylation Locomotion Cell Differentiation Positive Regulation Of Metabolic Process Histone Modification Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Innate Immune Response Signaling Response To Stimulus	Glutamate Secretion Glutamine Metabolic Process Regulation Of Glycoprotein Biosynthetic Process Glial Cell Differentiation In Utero Embryonic Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Gliogenesis Regulation Of Neurogenesis Centrosome Cycle Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Neurogenesis Acid Secretion Establishment Of Protein Localization To Juxtaparanode Region Of Axon Brain Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Cell Development Head Development Regulation Of Glial Cell Differentiation Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Development Positive Regulation Of Gene Expression RNA Biosynthetic Process Dicarboxylic Acid Transport Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Cell-cell Signaling Basophil Differentiation Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Centriole Replication Positive Regulation Of Adenosine Receptor Signaling Pathway Schwann Cell Proliferation Eosinophil Fate Commitment Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Telencephalon Cell Migration Biosynthetic Process Centrosome Organization Forebrain Cell Migration Regulation Of Gliogenesis Central Nervous System Development Neurotransmitter Secretion Microtubule Cytoskeleton Organization Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Eosinophil Differentiation Clustering Of Voltage-gated Potassium Channels
Tagcloud ?		aff2 algorithm arpp21 bioinformatics cacna2d3 degs depthfirst differentially downloaded economic enormous enrichment exonlevel gbm glioblastoma gliomas gse9385 hist1h3a hub impair od oligodendroglioma omnibus ontology ppi proteinprotein shared society splicing	anxa6 art atomic benchmarked biologically calu cdc42 differentially distinctive experimentally exploit feasibility identity integrating modeled modeling opposite pair pairs pipeline predictions proteomic ptbp1 solved splice splicing tasser translated variants
Tagcloud (Difference) ?		aff2 algorithm arpp21 bioinformatics cacna2d3 degs depthfirst downloaded economic enormous enrichment exonlevel gbm glioblastoma gliomas gse9385 hist1h3a hub impair od oligodendroglioma omnibus ontology ppi proteinprotein shared society	anxa6 art atomic benchmarked biologically calu cdc42 distinctive experimentally exploit feasibility identity integrating modeled modeling opposite pair pairs pipeline predictions proteomic ptbp1 solved splice tasser translated variants
Tagcloud (Intersection) ?		differentially splicing