TAX1BP3 and DTX1

Number of citations of the paper that reports this interaction (PMID 23395680)
1

Data Source:
BioGRID (fluorescent resonance energy transfer)

		TAX1BP3	DTX1
Gene Name		Tax1 (human T-cell leukemia virus type I) binding protein 3	deltex 1, E3 ubiquitin ligase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Actin Cytoskeleton Extracellular Vesicular Exosome	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Beta-catenin Binding Protein C-terminus Binding	Transcription Coactivator Activity Notch Binding Protein Binding Zinc Ion Binding Ligase Activity SH3 Domain Binding Ubiquitin Protein Ligase Binding
	Biological Process	Rho Protein Signal Transduction Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Activation Of Cdc42 GTPase Activity Negative Regulation Of Protein Localization To Cell Surface	Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Cell Surface Receptor Signaling Pathway Notch Signaling Pathway Regulation Of Notch Signaling Pathway Glial Cell Differentiation Protein Ubiquitination Negative Regulation Of T Cell Differentiation Negative Regulation Of Neuron Differentiation Regulation Of Nucleic Acid-templated Transcription
Pathways			Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Activated NOTCH1 Transmits Signal to the Nucleus Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS			Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		14 interactors: ARNT2 CDK5RAP3 CNTN2 CTNNB1 DTX1 GATA1 GLS GLS2 PLK4 RNF183 RTKN STAU1 TCEA2 TRIM29	20 interactors: DEFA5 DTX2 DTX3 DTX3L EP300 G3BP1 GRB2 ITCH MAP3K1 NOTCH1 NOTCH2 TAX1BP3 UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2N UBE2U
Entrez ID		30851	1840
HPRD ID		18160	03991
Ensembl ID		ENSG00000213977	ENSG00000135144
Uniprot IDs		O14907	Q86Y01
PDB IDs		2KG2 2L4S 2L4T 2VZ5 3GJ9 3SFJ 4E3B
Enriched GO Terms of Interacting Partners?		Glutamate Secretion Glutamine Metabolic Process Regulation Of Glycoprotein Biosynthetic Process Glial Cell Differentiation In Utero Embryonic Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Gliogenesis Regulation Of Neurogenesis Centrosome Cycle Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Neurogenesis Acid Secretion Establishment Of Protein Localization To Juxtaparanode Region Of Axon Brain Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Cell Development Head Development Regulation Of Glial Cell Differentiation Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Development Positive Regulation Of Gene Expression RNA Biosynthetic Process Dicarboxylic Acid Transport Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Cell-cell Signaling Basophil Differentiation Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Centriole Replication Positive Regulation Of Adenosine Receptor Signaling Pathway Schwann Cell Proliferation Eosinophil Fate Commitment Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Telencephalon Cell Migration Biosynthetic Process Centrosome Organization Forebrain Cell Migration Regulation Of Gliogenesis Central Nervous System Development Neurotransmitter Secretion Microtubule Cytoskeleton Organization Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Eosinophil Differentiation Clustering Of Voltage-gated Potassium Channels	Protein K48-linked Ubiquitination Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Pattern Recognition Receptor Signaling Pathway Notch Signaling Pathway Innate Immune Response-activating Signal Transduction Immune Response Activation Of Innate Immune Response Defense Response Ubiquitin-dependent Protein Catabolic Process Cellular Protein Metabolic Process Modification-dependent Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Innate Immune Response Positive Regulation Of Innate Immune Response Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Modification Process Cellular Response To Hypoxia Protein Catabolic Process Cellular Response To Decreased Oxygen Levels Histone Ubiquitination Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Regulation Of Innate Immune Response Immune Response-regulating Signaling Pathway Cell Surface Receptor Signaling Pathway Cellular Response To Stress Protein Metabolic Process Cellular Response To Stimulus Cellular Macromolecule Catabolic Process Immune System Process Response To Stress Positive Regulation Of Ubiquitin-protein Transferase Activity Response To Stimulus Positive Regulation Of Ligase Activity Positive Regulation Of Immune Response Signal Transduction Regulation Of Ubiquitin-protein Transferase Activity Protein K11-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Signaling Proteasomal Protein Catabolic Process Cell Communication Protein K63-linked Ubiquitination Mitotic Spindle Assembly Checkpoint
Tagcloud ?		anxa6 art atomic benchmarked biologically calu cdc42 differentially distinctive experimentally exploit feasibility identity integrating modeled modeling opposite pair pairs pipeline predictions proteomic ptbp1 solved splice splicing tasser translated variants	algae bioconversion diarrhetic dinophysistoxin dinophysistoxins distinctive distinguished dsp dtx2 dtxs eluted featured fragmentation imperative isomers mrm oa okadaic orbitrap poisoning polyether quick shellfish spectra toxins transitions unequivocal unless z
Tagcloud (Difference) ?		anxa6 art atomic benchmarked biologically calu cdc42 differentially experimentally exploit feasibility identity integrating modeled modeling opposite pair pairs pipeline predictions proteomic ptbp1 solved splice splicing tasser translated variants	algae bioconversion diarrhetic dinophysistoxin dinophysistoxins distinguished dsp dtx2 dtxs eluted featured fragmentation imperative isomers mrm oa okadaic orbitrap poisoning polyether quick shellfish spectra toxins transitions unequivocal unless z
Tagcloud (Intersection) ?		distinctive