SSTR5 and PEX5

Number of citations of the paper that reports this interaction (PMID 16012170)
16

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		SSTR5	PEX5
Gene Name		somatostatin receptor 5	peroxisomal biogenesis factor 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex
	Molecular Function	Somatostatin Receptor Activity Neuropeptide Binding	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Synaptic Transmission Negative Regulation Of Cell Proliferation Positive Regulation Of Cytokinesis Somatostatin Signaling Pathway Glucose Homeostasis Regulation Of Insulin Secretion Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS			IgG glycosylation ( 23382691)
Protein-Protein Interactions		8 interactors: ADCY10 CORT DRD2 GOPC PDZK1 PEX5 SST SSTR1	68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772
Entrez ID		6755	5830
HPRD ID		01677	02684
Ensembl ID		ENSG00000162009	ENSG00000139197
Uniprot IDs		P35346	B4DR50 B4E0T2 P50542
PDB IDs			1FCH 2C0L 2C0M 2J9Q 2W84 3R9A
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Synaptic Transmission Cerebral Cortex Neuron Differentiation Positive Regulation Of Multicellular Organism Growth Cell-cell Signaling Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Forebrain Development G-protein Coupled Receptor Signaling Pathway Cytoplasmic Sequestering Of CFTR Protein Regulation Of Multicellular Organism Growth Telencephalon Cell Migration Forebrain Cell Migration Spermatogenesis Male Gamete Generation Response To Drug Positive Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Protein Homotetramerization Digestion Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Neuromuscular Process Monocarboxylic Acid Transport Regulation Of Protein Transport Hormone-mediated Signaling Pathway Regulation Of Anion Transport Regulation Of Locomotion Involved In Locomotory Behavior Protein Import Into Peroxisome Matrix, Translocation Negative Regulation Of Dopamine Receptor Signaling Pathway Gamete Generation Positive Regulation Of Developmental Growth Negative Regulation Of Cell Proliferation Regulation Of Establishment Of Protein Localization Cytoplasmic Transport Negative Regulation Of Dopamine Secretion Protein Import Into Peroxisome Matrix, Docking Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Branching Morphogenesis Of A Nerve Neuron Migration Negative Regulation Of Voltage-gated Calcium Channel Activity Orbitofrontal Cortex Development Somatostatin Signaling Pathway Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of Protein Transport Brain Development Regulation Of Protein Localization Sexual Reproduction Head Development Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Protein Homooligomerization Hormone-mediated Apoptotic Signaling Pathway Regulation Of Dopamine Receptor Signaling Pathway	Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process
Tagcloud ?		camk1 centriole dkk1 enah endosome geo gpsm2 inference kcnq3 kpna2 lcn2 lef1 lysosome map2k6 multivesicular nkx2 nr5a1 nup62 ontology phosphoinositide sfrp4 slc4a3 sort1 stx1a subnetwork tbl3 transport tshb ube2c	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Difference) ?		camk1 centriole dkk1 enah endosome geo gpsm2 inference kcnq3 kpna2 lcn2 lef1 lysosome map2k6 multivesicular nkx2 nr5a1 nup62 ontology phosphoinositide sfrp4 slc4a3 sort1 stx1a subnetwork tbl3 transport tshb ube2c	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Intersection) ?