PEX5 and HOXA7

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PEX5	HOXA7
Gene Name		peroxisomal biogenesis factor 5	homeobox A7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex	Nucleus
	Molecular Function	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Transcription Factor Binding Sequence-specific DNA Binding
	Biological Process	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization	Negative Regulation Of Transcription From RNA Polymerase II Promoter Angiogenesis Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Leukocyte Migration Transcription, DNA-templated Anterior/posterior Pattern Specification Negative Regulation Of Keratinocyte Differentiation Negative Regulation Of Monocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Skeletal System Morphogenesis Stem Cell Differentiation
Pathways
Drugs
Diseases
GWAS		IgG glycosylation ( 23382691)
Protein-Protein Interactions		68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772	5 interactors: GMNN JUNB MEIS1 NPM1 PEX5
Entrez ID		5830	3204
HPRD ID		02684	00838
Ensembl ID		ENSG00000139197	ENSG00000122592
Uniprot IDs		B4DR50 B4E0T2 P50542	P31268
PDB IDs		1FCH 2C0L 2C0M 2J9Q 2W84 3R9A
Enriched GO Terms of Interacting Partners?		Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process	Regulation Of Endoribonuclease Activity Regulation Of EIF2 Alpha Phosphorylation By DsRNA Negative Regulation Of Protein Homotetramerization Regulation Of Cell Cycle Protein Import Into Peroxisome Matrix, Translocation Regulation Of Ribonuclease Activity Regulation Of Endodeoxyribonuclease Activity Developmental Process Protein Complex Assembly Protein Import Into Peroxisome Matrix, Docking Myeloid Cell Differentiation Organ Development Negative Regulation Of Protein Homooligomerization Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Protein Import Into Peroxisome Membrane Protein To Membrane Docking Peroxisomal Membrane Transport Osteoblast Proliferation Negative Regulation Of Protein Oligomerization Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Centriole Replication Embryonic Process Involved In Female Pregnancy Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Protein Import Into Peroxisome Matrix Blood Vessel Morphogenesis Protein Oligomerization Negative Regulation Of Centrosome Duplication Megakaryocyte Development Negative Regulation Of Cell Cycle System Development Blood Vessel Development Cellular Component Assembly Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Vasculature Development Megakaryocyte Differentiation Definitive Hemopoiesis Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Regulation Of RNA Metabolic Process Trophectodermal Cell Differentiation CENP-A Containing Nucleosome Assembly Labyrinthine Layer Blood Vessel Development Very Long-chain Fatty Acid Metabolic Process Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Negative Regulation Of Cellular Metabolic Process Lens Morphogenesis In Camera-type Eye
Tagcloud ?		behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled	cdk2 cdk4 changes contribute conversely cyclin define diagnostic downregulation e1 endogenous forced hcc hepatocellular hepg2 knockdown morphogenesis observations organogenesis progression proliferation promising promoted qgy qsg roles sirna strategies
Tagcloud (Difference) ?		behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled	cdk2 cdk4 changes contribute conversely cyclin define diagnostic downregulation e1 endogenous forced hcc hepatocellular hepg2 knockdown morphogenesis observations organogenesis progression proliferation promising promoted qgy qsg roles sirna strategies
Tagcloud (Intersection) ?