SP100 and SNIP1

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		SP100	SNIP1
Gene Name		SP100 nuclear antigen	Smad nuclear interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm PML Body Mre11 Complex Nuclear Periphery	Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Kinase Binding Protein Domain Specific Binding Identical Protein Binding Protein Homodimerization Activity Chromo Shadow Domain Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Telomere Maintenance Chromatin Remodeling Transcription, DNA-templated DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Endothelial Cell Migration Viral Process Cytokine-mediated Signaling Pathway Response To Retinoic Acid Negative Regulation Of Viral Transcription Response To Cytokine Response To Type I Interferon Response To Interferon-gamma Negative Regulation Of DNA Binding Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Angiogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Protein Export From Nucleus Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Cellular Component Movement Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Fas Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription	Regulation Of Transcription, DNA-templated I-kappaB Kinase/NF-kappaB Signaling Production Of MiRNAs Involved In Gene Silencing By MiRNA
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS
Protein-Protein Interactions		38 interactors: ACTN2 AMOTL2 ARID3A CASP8AP2 CBX1 CBX3 CBX5 CREM DNMT3A DYRK2 ETS1 GIPC2 HIPK2 L3MBTL3 LZTR1 MX1 MYB NIPBL PHC1 PML RANBP2 RBM39 RTP5 SAE1 SENP1 SNIP1 SUMO1 SUMO2 SUMO3 TERF1 TERF2 TERF2IP TRAF3IP3 TRIM29 UBA2 UBE2I USPL1 ZC2HC1A	40 interactors: C17orf85 CDK6 CHERP CLK2 CREBBP DVL2 EIF3C EP300 FAF1 GMEB1 HIPK1 HIPK3 MAX MFAP1 MYC PIAS1 PIAS2 PIAS4 PRPF3 PRPF40A RELA SETDB1 SF3B1 SMAD1 SMAD2 SMAD4 SON SP100 SRPK2 SRRM2 TDG TNIP1 TOPORS TTC14 UBE2I ZCCHC10 ZCCHC7 ZMYM2 ZMYM5 ZNF451
Entrez ID		6672	79753
HPRD ID		06844	06999
Ensembl ID		ENSG00000067066	ENSG00000163877
Uniprot IDs		E7EUA7 P23497 Q6ZMK3	B1AK66 Q8TAD8
PDB IDs		1H5P
Enriched GO Terms of Interacting Partners?		Protein Sumoylation PML Body Organization Regulation Of Metabolic Process Peptidyl-lysine Modification Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Telomere Maintenance Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Telomere Maintenance Post-translational Protein Modification Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Nucleus Organization Regulation Of Transcription, DNA-templated Peptidyl-amino Acid Modification Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Telomere Maintenance Via Telomerase Regulation Of Chromosome Organization Positive Regulation Of Metabolic Process Regulation Of Cellular Process SMT3-dependent Protein Catabolic Process Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Organelle Organization Positive Regulation Of Proteolysis RNA-dependent DNA Replication Positive Regulation Of Cellular Metabolic Process Telomeric Loop Formation Age-dependent Telomere Shortening Negative Regulation Of Chromosome Organization Chromosome Organization Telomere Maintenance Via Telomere Shortening Protection From Non-homologous End Joining At Telomere Protein Desumoylation Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomere Lengthening Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein Catabolic Process Telomere Capping Chromatin Modification Positive Regulation Of Cellular Protein Metabolic Process Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase	Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Protein Sumoylation Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Peptidyl-lysine Modification Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process RNA Processing Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Signal Transduction Regulation Of Cell Proliferation SMAD Protein Complex Assembly Peptidyl-amino Acid Modification Positive Regulation Of Metabolic Process Regulation Of Cellular Process Regulation Of Signaling Transcription From RNA Polymerase II Promoter Pattern Specification Process Positive Regulation Of Cellular Metabolic Process N-terminal Peptidyl-lysine Acetylation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Signal Transduction Regulation Of Cell Death
Tagcloud ?		aml1 autoregulatory cdnas cofactor deaf deformed deoxyribonuclease displaced dnase fetus germ immunocytochemistry inductions monkey mtg8 nonhomeodomain nudr oncoprotein prodynorphin proenkephalin rares shifts similarities testicular thymidine transfections transferable ttcg ttcgggnntttccgg	activates bcar4 ccl21 chemokine consequences consisting coordinated correlates enables extended gli2 h3k18ac hedgehog indirect lnas lncrna lncrnas locked noncanonical nucleic pnuts pol pp1 recruited releases relieve suppresses tumorigenic turn
Tagcloud (Difference) ?		aml1 autoregulatory cdnas cofactor deaf deformed deoxyribonuclease displaced dnase fetus germ immunocytochemistry inductions monkey mtg8 nonhomeodomain nudr oncoprotein prodynorphin proenkephalin rares shifts similarities testicular thymidine transfections transferable ttcg ttcgggnntttccgg	activates bcar4 ccl21 chemokine consequences consisting coordinated correlates enables extended gli2 h3k18ac hedgehog indirect lnas lncrna lncrnas locked noncanonical nucleic pnuts pol pp1 recruited releases relieve suppresses tumorigenic turn
Tagcloud (Intersection) ?