C3AR1

Gene Name		complement component 3a receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Phosphatidylinositol Phospholipase C Activity Complement Component C3a Receptor Activity G-protein Coupled Receptor Activity C3a Anaphylatoxin Receptor Activity
	Biological Process	Complement Receptor Mediated Signaling Pathway Chemotaxis Inflammatory Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Blood Circulation Metabolic Process Positive Regulation Vascular Endothelial Growth Factor Production Positive Regulation Of Macrophage Chemotaxis Positive Regulation Of Angiogenesis Positive Regulation Of Neutrophil Chemotaxis
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: C3 C4A SNTA1
Entrez ID		719
HPRD ID		05581
Ensembl ID		ENSG00000171860
Uniprot IDs		A8K2H7 Q16581
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Apoptotic Cell Clearance Regulation Of Apoptotic Cell Clearance Regulation Of Complement Activation Positive Regulation Of Phagocytosis Regulation Of Humoral Immune Response Regulation Of Phagocytosis Regulation Of Acute Inflammatory Response Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Positive Regulation Of Endocytosis Complement Activation, Classical Pathway Humoral Immune Response Mediated By Circulating Immunoglobulin Complement Activation Regulation Of Vasoconstriction By Circulating Norepinephrine Protein Activation Cascade Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Regulation Of Endocytosis Positive Regulation Of Type IIa Hypersensitivity Humoral Immune Response Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Negative Regulation Of Endopeptidase Activity Leukocyte Mediated Immunity Adaptive Immune Response Negative Regulation Of Peptidase Activity Regulation Of Inflammatory Response Positive Regulation Of Activation Of Membrane Attack Complex Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Negative Regulation Of Cellular Metabolic Process Regulation Of Vesicle-mediated Transport Regulation Of Endopeptidase Activity Positive Regulation Of Hypersensitivity Regulation Of Protein Metabolic Process Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Inflammatory Response Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Complement Activation, Alternative Pathway Positive Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Positive Regulation Of Humoral Immune Response Positive Regulation Of Immune Response Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Proteolysis Positive Regulation Of Protein Processing Regulation Of Triglyceride Biosynthetic Process
Tagcloud ?		african chabaudi cope demonstration falciparum fcgr3b highlighted hosts implicate implicating interplay lrrc25 malaria mapped mounted noncoding plasmodium polygenic rad21 responders retn sco1 signature slc39a8 slc3a2 tapbp transcriptomes validated west