SNAP25 and SYT9

Number of citations of the paper that reports this interaction (PMID 12062043)
65

Data Source:
HPRD (in vitro)

		SNAP25	SYT9
Gene Name		synaptosomal-associated protein, 25kDa	synaptotagmin IX
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Trans-Golgi Network Cytosol Plasma Membrane Membrane Cell Junction Growth Cone BLOC-1 Complex SNARE Complex Vesicle Presynaptic Membrane Neuron Projection Perinuclear Region Of Cytoplasm Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex	Integral Component Of Membrane Cell Junction Secretory Granule Membrane Synaptic Vesicle Membrane Dense Core Granule
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin-1 Binding Calcium-dependent Protein Binding	Transporter Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Neurotransmitter Uptake Energy Reserve Metabolic Process Synaptic Transmission Neurotransmitter Secretion Pathogenesis Regulation Of Neuron Projection Development Glutamate Secretion Synaptic Vesicle Exocytosis Synaptic Vesicle Docking Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Small Molecule Metabolic Process Regulation Of Insulin Secretion Long-term Synaptic Potentiation Regulation Of Establishment Of Protein Localization	Transport Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Insulin Secretion
Pathways		Dopamine Neurotransmitter Release Cycle Integration of energy metabolism Toxicity of botulinum toxin type E (BoNT/E) Toxicity of botulinum toxin type A (BoNT/A) Acetylcholine Neurotransmitter Release Cycle Regulation of insulin secretion Toxicity of botulinum toxin type C (BoNT/C) Norepinephrine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation Glutamate Neurotransmitter Release Cycle Uptake and actions of bacterial toxins Neurotransmitter Release Cycle Neurotoxicity of clostridium toxins Serotonin Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs		Botulinum Toxin Type A
Diseases
GWAS		Cardiac hypertrophy ( 21348951)	Phospholipid levels (plasma) ( 22359512)
Protein-Protein Interactions		34 interactors: APP CCDC53 CENPF CPLX1 DNM1 GOSR1 HGS ITSN1 KCNB1 KIF5B NAPA PRKACA PRKCA PRRT2 RIMS1 SCAMP1 SNAPIN SRCIN1 STX11 STX12 STX1A STX2 STX3 STX4 STX5 STXBP6 SYT1 SYT3 SYT9 TRIM9 VAMP2 VAMP7 VAMP8 ZDHHC17	6 interactors: CSNK1A1 NRXN1 SNAP25 SYNCRIP TRPV1 TUBB
Entrez ID		6616	143425
HPRD ID		02637	11618
Ensembl ID		ENSG00000132639	ENSG00000170743
Uniprot IDs		P60880	Q86SS6
PDB IDs		1KIL 1XTG 3RK2 3RK3 3RL0 3ZUR
Enriched GO Terms of Interacting Partners?		Membrane Fusion Exocytosis Vesicle-mediated Transport Vesicle Fusion Synaptic Vesicle Exocytosis Synaptic Vesicle Transport Establishment Of Localization In Cell Secretion By Cell Organelle Fusion Establishment Of Vesicle Localization Vesicle Localization Regulation Of Exocytosis Secretion Neurotransmitter Secretion Cellular Localization Transport Establishment Of Organelle Localization Regulation Of Cellular Localization Synaptic Transmission Regulation Of Neurotransmitter Levels Regulation Of Secretion Organelle Localization Neurotransmitter Transport Membrane Organization Regulation Of Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Membrane Protein Transport Vesicle Organization Establishment Of Protein Localization Cell-cell Signaling Vesicle Docking Intracellular Transport Membrane Docking Protein Localization Positive Regulation Of Exocytosis Calcium Ion-dependent Exocytosis Regulation Of Hormone Secretion Intracellular Protein Transport Regulation Of Cellular Component Organization Positive Regulation Of Transport Glutamate Secretion Regulation Of Synaptic Transmission Golgi Vesicle Transport Post-Golgi Vesicle-mediated Transport Regulation Of Protein Localization Positive Regulation Of Synaptic Transmission Regulation Of Insulin Secretion Cellular Protein Localization Regulation Of Peptide Hormone Secretion Acid Secretion	Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Neurotransmitter Secretion Positive Regulation Of Synaptic Transmission Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Regulation Of Neurotransmitter Levels Neurotransmitter Transport Gephyrin Clustering Synaptic Vesicle Clustering Thermoception Neuronal Signal Transduction Regulation Of Insulin Secretion Vesicle Localization N-methyl-D-aspartate Receptor Clustering Vocal Learning CRD-mediated MRNA Stabilization Regulation Of Peptide Hormone Secretion Negative Regulation Of Filopodium Assembly Postsynaptic Membrane Assembly Protein Complex Assembly Synapse Maturation Regulation Of Grooming Behavior Regulation Of Hormone Secretion Transport Synaptic Vesicle Docking Presynaptic Membrane Assembly Postsynaptic Density Protein 95 Clustering Synaptic Vesicle Priming Cellular Response To ATP Receptor Localization To Synapse Regulation Of Synaptic Transmission Presynaptic Membrane Organization Auditory Behavior Synaptic Vesicle Fusion To Presynaptic Membrane Cellular Protein Complex Assembly Neurotransmitter Uptake Cerebellar Granule Cell Differentiation Vocalization Behavior Prepulse Inhibition Neuron Cell-cell Adhesion Regulation Of Protein Secretion Chemosensory Behavior Positive Regulation Of Synapse Maturation Mechanosensory Behavior Cerebellar Granular Layer Morphogenesis Organelle Localization Cell Division Response To Auditory Stimulus Regulation Of Synapse Maturation
Tagcloud ?		anterograde axonal axons blunt breakdown bulbous bulbs caudate circumscribed disorganized immunocytochemical immunoreactivity insult map5 mca neurofilament nf68kd nonischemic occlusion permeating precedes reminiscent roughened sequalae subcortical swellings synaptosomal territory tracts
Tagcloud (Difference) ?		anterograde axonal axons blunt breakdown bulbous bulbs caudate circumscribed disorganized immunocytochemical immunoreactivity insult map5 mca neurofilament nf68kd nonischemic occlusion permeating precedes reminiscent roughened sequalae subcortical swellings synaptosomal territory tracts
Tagcloud (Intersection) ?