MICAL1 and RAB10

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MICAL1	RAB10
Gene Name		microtubule associated monooxygenase, calponin and LIM domain containing 1	RAB10, member RAS oncogene family
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Intermediate Filament	Exocyst Endosome Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Plasma Membrane Focal Adhesion Endosome Membrane Cytoplasmic Vesicle Membrane Phagocytic Vesicle Membrane Insulin-responsive Compartment Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome Endoplasmic Reticulum Tubular Network Primary Cilium
	Molecular Function	Actin Binding Protein Binding Zinc Ion Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen SH3 Domain Binding Rab GTPase Binding FAD Binding	GTPase Activity GTP Binding GDP Binding Myosin V Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Cytoskeleton Organization Signal Transduction Sulfur Oxidation Actin Filament Depolymerization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Oxidation-reduction Process	Intracellular Protein Transport Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Axonogenesis Protein Secretion Vesicle-mediated Transport Endosomal Transport Regulation Of Exocytosis Antigen Processing And Presentation Polarized Epithelial Cell Differentiation Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Establishment Of Neuroblast Polarity Membrane Organization Basolateral Protein Localization Endoplasmic Reticulum Tubular Network Organization Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Membrane
Pathways			Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS			Immune response to smallpox vaccine (IL-6) ( 22542470) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Metabolite levels (HVA/MHPG ratio) ( 23319000)
Protein-Protein Interactions		16 interactors: ABL1 CRK EHD1 GADD45A GRB2 GSK3B NEDD9 PIK3R3 PTK2 RAB10 RAB1A RAB1B RPS6KA6 SRC TAB1 VIM	9 interactors: APP ENOPH1 EVI5L MICAL1 MTNR1A OPTN PPBP RIMS1 SEPT9
Entrez ID		64780	10890
HPRD ID		06183	06692
Ensembl ID		ENSG00000135596	ENSG00000084733
Uniprot IDs		Q8TDZ2	P61026
PDB IDs		1WYL 2CO8 2DK9
Enriched GO Terms of Interacting Partners?		Fc Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Stimulus Regulation Of Phosphorylation Signal Transduction Regulation Of MAPK Cascade Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Signaling Cell Morphogenesis Involved In Differentiation Cell Communication Immune Response-regulating Signaling Pathway Cellular Response To Organonitrogen Compound Regulation Of Kinase Activity Neuron Projection Development Positive Regulation Of Protein Metabolic Process Axonogenesis Cell Development Cellular Response To Peptide Hormone Stimulus Axon Development Cellular Response To Growth Factor Stimulus Response To Stimulus Cellular Response To Peptide Intracellular Signal Transduction Cell Morphogenesis Involved In Neuron Differentiation Cellular Response To Organic Substance Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Response To Growth Factor Neuron Development Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Vesicle-mediated Transport Neuron Projection Morphogenesis Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Cell Morphogenesis Generation Of Neurons Positive Regulation Of Protein Phosphorylation Neuron Differentiation Blood Coagulation Cellular Response To Insulin Stimulus Hemostasis Regulation Of Protein Kinase Activity Ras Protein Signal Transduction Cell Projection Organization Neurogenesis Response To Peptide Hormone	Mating Behavior Mating Exocytosis Platelet Degranulation Secretion By Cell Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Negative Regulation Of Cilium Assembly Vesicle-mediated Transport Secretion Negative Regulation Of Receptor Recycling Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Defense Response To Bacterium Platelet Activation Axon Choice Point Recognition Golgi Ribbon Formation Sulfur Oxidation
Tagcloud ?			a8 a9 aldehyde aldh3a1 beta4 biglycan chymase cma1 conjunctiva conjunctival fibrovascular gelsolin genechip immunofluorescent infiltrates itraq member1 pterygium s100 s100a8 s100a9 sawdust serpin serpina1 stringent thymosin uninvolved vim wing
Tagcloud (Difference) ?			a8 a9 aldehyde aldh3a1 beta4 biglycan chymase cma1 conjunctiva conjunctival fibrovascular gelsolin genechip immunofluorescent infiltrates itraq member1 pterygium s100 s100a8 s100a9 sawdust serpin serpina1 stringent thymosin uninvolved vim wing
Tagcloud (Intersection) ?