MICAL1 and RAB1B

Number of citations of the paper that reports this interaction (PMID 15796781)
3

Data Source:
HPRD (two hybrid)

		MICAL1	RAB1B
Gene Name		microtubule associated monooxygenase, calponin and LIM domain containing 1	RAB1B, member RAS oncogene family
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Gene Ontology Annotations	Cellular Component	Cytoplasm Intermediate Filament	Golgi Membrane Mitochondrion Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Pre-autophagosomal Structure Membrane Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Protein Binding Zinc Ion Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen SH3 Domain Binding Rab GTPase Binding FAD Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Cytoskeleton Organization Signal Transduction Sulfur Oxidation Actin Filament Depolymerization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Oxidation-reduction Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Autophagy Virion Assembly Rab Protein Signal Transduction Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagic Vacuole Assembly
Pathways			Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		16 interactors: ABL1 CRK EHD1 GADD45A GRB2 GSK3B NEDD9 PIK3R3 PTK2 RAB10 RAB1A RAB1B RPS6KA6 SRC TAB1 VIM	10 interactors: APP CHM GDI1 GOLGA2 MICAL1 MICAL3 MICALCL RUSC2 SMARCC2 TOMM40L
Entrez ID		64780	81876
HPRD ID		06183	11469
Ensembl ID		ENSG00000135596	ENSG00000174903
Uniprot IDs		Q8TDZ2	E9PLD0 Q9H0U4
PDB IDs		1WYL 2CO8 2DK9	3JZA 3NKV 4HLQ 4I1O
Enriched GO Terms of Interacting Partners?		Fc Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Stimulus Regulation Of Phosphorylation Signal Transduction Regulation Of MAPK Cascade Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Signaling Cell Morphogenesis Involved In Differentiation Cell Communication Immune Response-regulating Signaling Pathway Cellular Response To Organonitrogen Compound Regulation Of Kinase Activity Neuron Projection Development Positive Regulation Of Protein Metabolic Process Axonogenesis Cell Development Cellular Response To Peptide Hormone Stimulus Axon Development Cellular Response To Growth Factor Stimulus Response To Stimulus Cellular Response To Peptide Intracellular Signal Transduction Cell Morphogenesis Involved In Neuron Differentiation Cellular Response To Organic Substance Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Response To Growth Factor Neuron Development Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Vesicle-mediated Transport Neuron Projection Morphogenesis Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Cell Morphogenesis Generation Of Neurons Positive Regulation Of Protein Phosphorylation Neuron Differentiation Blood Coagulation Cellular Response To Insulin Stimulus Hemostasis Regulation Of Protein Kinase Activity Ras Protein Signal Transduction Cell Projection Organization Neurogenesis Response To Peptide Hormone	Actin Filament Depolymerization Protein Complex Disassembly Actin Polymerization Or Depolymerization Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Protein Targeting To Membrane Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Protein Complex Disassembly Axon Choice Point Recognition Sulfur Oxidation Negative Regulation Of Neuron Differentiation Protein Geranylgeranylation
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