SH3GL1 and B3GAT1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SH3GL1	B3GAT1
Gene Name		SH3-domain GRB2-like 1	beta-1,3-glucuronyltransferase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Podosome Cytoplasm Cell Junction Early Endosome Membrane Cell Projection	Golgi Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Lipid Binding Phosphatase Binding Identical Protein Binding GTPase Binding	UDP-galactose:beta-N-acetylglucosamine Beta-1,3-galactosyltransferase Activity Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Activity Metal Ion Binding
	Biological Process	Endocytosis Signal Transduction Central Nervous System Development	Carbohydrate Metabolic Process Protein Glycosylation Pathogenesis Glycosaminoglycan Metabolic Process Chondroitin Sulfate Metabolic Process Small Molecule Metabolic Process
Pathways			MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Heparan sulfate/heparin (HS-GAG) metabolism Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Chondroitin sulfate/dermatan sulfate metabolism Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism Defective CHST14 causes EDS, musculocontractural type Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Defective CHST6 causes MCDC1 Glycogen storage diseases MPS IIID - Sanfilippo syndrome D A tetrasaccharide linker sequence is required for GAG synthesis MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A MPS IV - Morquio syndrome B Defective CHSY1 causes TPBS MPS VII - Sly syndrome Metabolism of carbohydrates MPS VI - Maroteaux-Lamy syndrome
Drugs			D-tartaric acid Uridine-5\'-Diphosphate
Diseases
GWAS
Protein-Protein Interactions		26 interactors: ARHGAP8 AXIN1 B3GAT1 CREBBP DNM1 DNM1L DPPA4 DPYSL4 FAM102A GPKOW ITSN2 LRRK2 MAL2 MTA1 PDCD6IP PML PTPRO SEPT8 SH2D4A SH3D19 SH3GL2 SH3GL3 SYNJ1 VIM VPS37C YWHAZ	2 interactors: HLA-DMA SH3GL1
Entrez ID		6455	27087
HPRD ID		03462	06969
Ensembl ID		ENSG00000141985	ENSG00000109956
Uniprot IDs		Q6FGM0 Q99961	F5H0S0 Q9P2W7
PDB IDs			1V82 1V83 1V84
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Positive Regulation Of Protein Autoubiquitination Endocytosis Regulation Of Protein Autoubiquitination Regulation Of Cellular Component Organization Protein Localization To Mitochondrion Regulation Of Cellular Localization Regulation Of Protein Ubiquitination Cellular Localization Cell Death Death Regulation Of Mitochondrial Fission Regulation Of Signaling Organelle Organization Regulation Of Mitochondrion Organization Membrane Organization Cell Part Morphogenesis Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Viral Process Positive Regulation Of Proteolysis Entrainment Of Circadian Clock By Photoperiod Signaling Cell Development Virion Assembly Transport Apoptotic Process Cell Communication Photoperiodism Entrainment Of Circadian Clock Positive Regulation Of Protein Ubiquitination Anatomical Structure Morphogenesis Neuron Projection Morphogenesis Programmed Cell Death Regulation Of Vesicle-mediated Transport Signal Transduction Regulation Of Protein Catabolic Process Axon Guidance Synaptic Vesicle Endocytosis Generation Of Neurons Synaptic Vesicle Recycling Positive Regulation Of Organelle Organization Neuron Differentiation Organelle Localization Regulation Of Synaptic Vesicle Transport Regulation Of Intracellular Transport Neurogenesis Positive Regulation Of Apoptotic Signaling Pathway Neuron Projection Development Positive Regulation Of Synaptic Vesicle Uncoating	Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Assembly Positive Thymic T Cell Selection Thymic T Cell Selection Chaperone Mediated Protein Folding Requiring Cofactor Positive T Cell Selection T Cell Selection 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Chaperone-mediated Protein Folding T Cell Differentiation In Thymus
Tagcloud ?		antigens array autoantibodies autoantibody autologous c6 clarification cloning curable deletion elicit elisa epitope establishment glioma gliomas grade grb2 homology immunological mutants oncogenic overlap serex serological spite subtle usually volunteers
Tagcloud (Difference) ?		antigens array autoantibodies autoantibody autologous c6 clarification cloning curable deletion elicit elisa epitope establishment glioma gliomas grade grb2 homology immunological mutants oncogenic overlap serex serological spite subtle usually volunteers
Tagcloud (Intersection) ?