SH3GL1 and PDCD6IP

Number of citations of the paper that reports this interaction (PMID 12034747)
39

Data Source:
HPRD (in vivo, two hybrid)

		SH3GL1	PDCD6IP
Gene Name		SH3-domain GRB2-like 1	programmed cell death 6 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Podosome Cytoplasm Cell Junction Early Endosome Membrane Cell Projection	Immunological Synapse Cytoplasm Microtubule Organizing Center Cytosol Focal Adhesion Membrane Vesicle Melanosome Extracellular Vesicular Exosome Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Lipid Binding Phosphatase Binding Identical Protein Binding GTPase Binding	Protein Binding SH3 Domain Binding Proteinase Activated Receptor Binding Protein Homodimerization Activity Calcium-dependent Protein Binding
	Biological Process	Endocytosis Signal Transduction Central Nervous System Development	Cell Separation After Cytokinesis Apoptotic Process Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Viral Life Cycle Viral Budding Via Host ESCRT Complex Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Extracellular Vesicular Exosome Assembly
Pathways			HIV Life Cycle Budding and maturation of HIV virion Uptake and actions of bacterial toxins HIV Infection Uptake and function of anthrax toxins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS			Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		26 interactors: ARHGAP8 AXIN1 B3GAT1 CREBBP DNM1 DNM1L DPPA4 DPYSL4 FAM102A GPKOW ITSN2 LRRK2 MAL2 MTA1 PDCD6IP PML PTPRO SEPT8 SH2D4A SH3D19 SH3GL2 SH3GL3 SYNJ1 VIM VPS37C YWHAZ	35 interactors: ARRDC1 ARRDC3 ATN1 CD2AP CEP55 CHMP4A CHMP4B CHMP4C CXCR1 EGFR F2R GRB2 HOXA1 ITSN1 ITSN2 KEAP1 MAPK6 PDCD6 PTK2B RAMP3 RNF11 SDCBP SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SH3RF1 SRC TAB1 TNIP2 TSG101 TTF2 VPS28 VPS37C YES1
Entrez ID		6455	10015
HPRD ID		03462	06425
Ensembl ID		ENSG00000141985	ENSG00000170248
Uniprot IDs		Q6FGM0 Q99961	C5MQH7 Q8WUM4
PDB IDs			2OEV 2OEW 2OEX 2OJQ 2R02 2R03 2R05 2XS1 2XS8 2ZNE 3C3O 3C3Q 3C3R 3E1R 4JJY
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Positive Regulation Of Protein Autoubiquitination Endocytosis Regulation Of Protein Autoubiquitination Regulation Of Cellular Component Organization Protein Localization To Mitochondrion Regulation Of Cellular Localization Regulation Of Protein Ubiquitination Cellular Localization Cell Death Death Regulation Of Mitochondrial Fission Regulation Of Signaling Organelle Organization Regulation Of Mitochondrion Organization Membrane Organization Cell Part Morphogenesis Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Viral Process Positive Regulation Of Proteolysis Entrainment Of Circadian Clock By Photoperiod Signaling Cell Development Virion Assembly Transport Apoptotic Process Cell Communication Photoperiodism Entrainment Of Circadian Clock Positive Regulation Of Protein Ubiquitination Anatomical Structure Morphogenesis Neuron Projection Morphogenesis Programmed Cell Death Regulation Of Vesicle-mediated Transport Signal Transduction Regulation Of Protein Catabolic Process Axon Guidance Synaptic Vesicle Endocytosis Generation Of Neurons Synaptic Vesicle Recycling Positive Regulation Of Organelle Organization Neuron Differentiation Organelle Localization Regulation Of Synaptic Vesicle Transport Regulation Of Intracellular Transport Neurogenesis Positive Regulation Of Apoptotic Signaling Pathway Neuron Projection Development Positive Regulation Of Synaptic Vesicle Uncoating	Virion Assembly Locomotion Endocytosis Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Cell Migration Cell Separation After Cytokinesis Membrane Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Axon Guidance Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Chemotaxis Viral Budding Transport Regulation Of Signal Transduction Viral Life Cycle Regulation Of Cellular Process Establishment Of Protein Localization Endosomal Transport Viral Protein Processing Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Axonogenesis Positive Regulation Of Cellular Metabolic Process Negative Regulation Of ERBB Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Signal Transduction Viral Process Axon Development Regulation Of Signaling Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development Regulation Of MAPK Cascade Neuron Projection Morphogenesis Regulation Of Intracellular Signal Transduction Cell Projection Organization Response To Organic Substance Multicellular Organismal Development Regulation Of Organelle Organization Response To External Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vacuolar Transport Positive Regulation Of Metabolic Process Intracellular Transport Neuron Development Anatomical Structure Development Apoptotic Process Cell Morphogenesis Involved In Differentiation
Tagcloud ?		antigens array autoantibodies autoantibody autologous c6 clarification cloning curable deletion elicit elisa epitope establishment glioma gliomas grade grb2 homology immunological mutants oncogenic overlap serex serological spite subtle usually volunteers	129n 146n adjuvanted arepanrix batch batches deamidation dige dioxidation fabp focetria gallus glycosylation h1n1 ha1 ha2 hemagglutinin latticed ma1 manufacturing narcolepsy neuraminidase nucleoprotein pandemrix ph1n1 sulfation tspan8 tub vaccines
Tagcloud (Difference) ?		antigens array autoantibodies autoantibody autologous c6 clarification cloning curable deletion elicit elisa epitope establishment glioma gliomas grade grb2 homology immunological mutants oncogenic overlap serex serological spite subtle usually volunteers	129n 146n adjuvanted arepanrix batch batches deamidation dige dioxidation fabp focetria gallus glycosylation h1n1 ha1 ha2 hemagglutinin latticed ma1 manufacturing narcolepsy neuraminidase nucleoprotein pandemrix ph1n1 sulfation tspan8 tub vaccines
Tagcloud (Intersection) ?