SH3GL1 and ARHGAP8

Number of citations of the paper that reports this interaction (PMID 15944398)
10

Data Source:
HPRD (in vitro, in vivo)

		SH3GL1	ARHGAP8
Gene Name		SH3-domain GRB2-like 1	Rho GTPase activating protein 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Podosome Cytoplasm Cell Junction Early Endosome Membrane Cell Projection	Cytosol
	Molecular Function	Protein Binding Lipid Binding Phosphatase Binding Identical Protein Binding GTPase Binding	Rho GTPase Activator Activity Protein Binding
	Biological Process	Endocytosis Signal Transduction Central Nervous System Development	Small GTPase Mediated Signal Transduction Positive Regulation Of Rho GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade
Pathways			Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS			Electroencephalographic traits in alcoholism ( 22554406)
Protein-Protein Interactions		26 interactors: ARHGAP8 AXIN1 B3GAT1 CREBBP DNM1 DNM1L DPPA4 DPYSL4 FAM102A GPKOW ITSN2 LRRK2 MAL2 MTA1 PDCD6IP PML PTPRO SEPT8 SH2D4A SH3D19 SH3GL2 SH3GL3 SYNJ1 VIM VPS37C YWHAZ	4 interactors: BNIP2 CTTN RHOA SH3GL1
Entrez ID		6455	23779
HPRD ID		03462	06448
Ensembl ID		ENSG00000141985	ENSG00000241484
Uniprot IDs		Q6FGM0 Q99961	A6ZJ79 P85298 Q6PJW1
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Positive Regulation Of Protein Autoubiquitination Endocytosis Regulation Of Protein Autoubiquitination Regulation Of Cellular Component Organization Protein Localization To Mitochondrion Regulation Of Cellular Localization Regulation Of Protein Ubiquitination Cellular Localization Cell Death Death Regulation Of Mitochondrial Fission Regulation Of Signaling Organelle Organization Regulation Of Mitochondrion Organization Membrane Organization Cell Part Morphogenesis Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Viral Process Positive Regulation Of Proteolysis Entrainment Of Circadian Clock By Photoperiod Signaling Cell Development Virion Assembly Transport Apoptotic Process Cell Communication Photoperiodism Entrainment Of Circadian Clock Positive Regulation Of Protein Ubiquitination Anatomical Structure Morphogenesis Neuron Projection Morphogenesis Programmed Cell Death Regulation Of Vesicle-mediated Transport Signal Transduction Regulation Of Protein Catabolic Process Axon Guidance Synaptic Vesicle Endocytosis Generation Of Neurons Synaptic Vesicle Recycling Positive Regulation Of Organelle Organization Neuron Differentiation Organelle Localization Regulation Of Synaptic Vesicle Transport Regulation Of Intracellular Transport Neurogenesis Positive Regulation Of Apoptotic Signaling Pathway Neuron Projection Development Positive Regulation Of Synaptic Vesicle Uncoating	Regulation Of Neuron Differentiation Nervous System Development Regulation Of Neurogenesis Regulation Of Cell Development Regulation Of Axonogenesis Cell Junction Assembly Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Cell-cell Junction Organization Skeletal Muscle Satellite Cell Migration Apolipoprotein A-I-mediated Signaling Pathway System Development Positive Regulation Of Cellular Component Biogenesis Cleavage Furrow Formation Generation Of Neurons Regulation Of Cell Differentiation Positive Regulation Of Neuron Differentiation Dendritic Spine Maintenance Neurogenesis Regulation Of Actin Cytoskeleton Organization Regulation Of Neuron Projection Development Substrate-dependent Cell Migration, Cell Extension Multicellular Organismal Development Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Positive Regulation Of Neurogenesis Anatomical Structure Development Microtubule Cytoskeleton Organization Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Cell Development Ossification Involved In Bone Maturation Developmental Process Bone Maturation Negative Chemotaxis Mitotic Spindle Assembly Dendritic Spine Organization Actin Cytoskeleton Organization Positive Regulation Of NF-kappaB Import Into Nucleus Regulation Of Osteoblast Proliferation Cellular Component Maintenance Neuron Projection Morphogenesis Actin Filament-based Process Endocytosis Focal Adhesion Assembly Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Signal Transduction Substrate-dependent Cell Migration Microtubule-based Process
Tagcloud ?		antigens array autoantibodies autoantibody autologous c6 clarification cloning curable deletion elicit elisa epitope establishment glioma gliomas grade grb2 homology immunological mutants oncogenic overlap serex serological spite subtle usually volunteers
Tagcloud (Difference) ?		antigens array autoantibodies autoantibody autologous c6 clarification cloning curable deletion elicit elisa epitope establishment glioma gliomas grade grb2 homology immunological mutants oncogenic overlap serex serological spite subtle usually volunteers
Tagcloud (Intersection) ?