CCL17 and ACKR1

Number of citations of the paper that reports this interaction (PMID 13679391)
13

Data Source:
HPRD (in vivo)

		CCL17	ACKR1
Gene Name		chemokine (C-C motif) ligand 17	atypical chemokine receptor 1 (Duffy blood group)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Early Endosome Plasma Membrane Integral Component Of Membrane Recycling Endosome
	Molecular Function	Receptor Binding Chemokine Activity CCR4 Chemokine Receptor Binding	Receptor Activity Transmembrane Signaling Receptor Activity G-protein Coupled Receptor Activity C-C Chemokine Binding
	Biological Process	Chemotaxis Inflammatory Response Immune Response G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling Multicellular Organismal Development Negative Regulation Of Myoblast Differentiation Cell Chemotaxis	Defense Response Inflammatory Response G-protein Coupled Receptor Signaling Pathway Regulation Of Chemokine Production Chemokine-mediated Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ACKR1 CCR4 CCR8 VCAM1	8 interactors: CCL17 CCL2 CCL5 CCL7 CCL8 CXCL1 CXCL5 CXCL8
Entrez ID		6361	2532
HPRD ID		03309	00192
Ensembl ID		ENSG00000102970	ENSG00000213088
Uniprot IDs		Q92583	Q16570 Q5Y7A1 Q5Y7A2
PDB IDs		1NR2 1NR4
Enriched GO Terms of Interacting Partners?		Chemokine-mediated Signaling Pathway Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Response To Cytokine Inflammatory Response Cellular Response To Organic Substance Cellular Chemical Homeostasis Chemotaxis Cellular Homeostasis Response To Organic Substance Chemical Homeostasis Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Surface Receptor Signaling Pathway Positive Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Cytosolic Calcium Ion Homeostasis G-protein Coupled Receptor Signaling Pathway Nuclear-transcribed MRNA Catabolic Process, No-go Decay Locomotion Immune Response Defense Response Homeostatic Process Membrane To Membrane Docking Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Regulation Of Cytoplasmic MRNA Processing Body Assembly Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Tolerance Induction Chorio-allantoic Fusion Cytoplasmic MRNA Processing Body Assembly Cellular Metal Ion Homeostasis Response To External Stimulus Cellular Cation Homeostasis Response To Radiation Cellular Ion Homeostasis Leukocyte Tethering Or Rolling Chronic Inflammatory Response Response To Extracellular Stimulus Metal Ion Homeostasis Response To Bacterium Signal Transduction Immune System Process Signaling Ion Homeostasis Cell Communication Labyrinthine Layer Morphogenesis Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Positive Regulation Of Organelle Assembly	Cell Chemotaxis Inflammatory Response Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Leukocyte Migration Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Leukocyte Migration Positive Regulation Of Behavior Regulation Of Chemotaxis Cell Migration Chemokine-mediated Signaling Pathway Cell Motility Regulation Of Behavior Locomotion Immune Response Defense Response Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Movement Of Cell Or Subcellular Component Positive Regulation Of Locomotion Response To External Stimulus Granulocyte Chemotaxis Immune System Process Regulation Of Cell Migration Regulation Of Cell Motility Monocyte Chemotaxis Regulation Of Locomotion Regulation Of Cellular Component Movement Response To Other Organism Response To Lipopolysaccharide Leukocyte Chemotaxis Response To Biotic Stimulus Response To Molecule Of Bacterial Origin Positive Regulation Of Immune System Process Regulation Of Lymphocyte Migration Cytokine-mediated Signaling Pathway Response To Bacterium Regulation Of Granulocyte Chemotaxis Response To Stress G-protein Coupled Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Leukocyte Migration Regulation Of Immune System Process Cellular Response To Interleukin-1 Positive Regulation Of Natural Killer Cell Chemotaxis Response To Cytokine Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Positive Regulation Of Macrophage Chemotaxis
Tagcloud ?		addresses adoptive airway antiviral attributable bronchiolitis challenge challenged eosinophil eosinophilia eosinophilic eosinophils eotaxin fi formalin immunized inactivated inadequately lungs partly pulmonary recovered rsv syncytial tarc th2 titers vaccination wheezing
Tagcloud (Difference) ?		addresses adoptive airway antiviral attributable bronchiolitis challenge challenged eosinophil eosinophilia eosinophilic eosinophils eotaxin fi formalin immunized inactivated inadequately lungs partly pulmonary recovered rsv syncytial tarc th2 titers vaccination wheezing
Tagcloud (Intersection) ?