SCP2 and PEX5

Number of citations of the paper that reports this interaction (PMID 20178365)
7

Data Source:
BioGRID (unspecified method)

		SCP2	PEX5
Gene Name		sterol carrier protein 2	peroxisomal biogenesis factor 5
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Peroxisome Peroxisomal Matrix Membrane Intracellular Membrane-bounded Organelle Protein Complex Extracellular Vesicular Exosome	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex
	Molecular Function	Fatty-acyl-CoA Binding Receptor Binding Protein Binding Phosphatidylinositol Transporter Activity Cholesterol Binding Propanoyl-CoA C-acyltransferase Activity Long-chain Fatty Acyl-CoA Binding Oleic Acid Binding	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	Steroid Biosynthetic Process Bile Acid Biosynthetic Process Progesterone Biosynthetic Process Lipid Transport Peroxisome Organization Bile Acid Metabolic Process Phospholipid Transport Positive Regulation Of Intracellular Cholesterol Transport Inositol Trisphosphate Biosynthetic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Unsaturated Fatty Acid Metabolic Process Alpha-linolenic Acid Metabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Steroid Metabolic Process Protein Localization To Plasma Membrane Lipid Hydroperoxide Transport	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization
Pathways		Metabolism of lipids and lipoproteins alpha-linolenic acid (ALA) metabolism alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
Drugs
Diseases
GWAS			IgG glycosylation ( 23382691)
Protein-Protein Interactions		8 interactors: ACAA2 ACOX1 CACNA1A CAV1 EHHADH PEX5 PITPNA TRIP13	68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772
Entrez ID		6342	5830
HPRD ID		01700	02684
Ensembl ID		ENSG00000116171	ENSG00000139197
Uniprot IDs		B2R761 E9PLD1 P22307 Q59HG9	B4DR50 B4E0T2 P50542
PDB IDs		1QND 2C0L	1FCH 2C0L 2C0M 2J9Q 2W84 3R9A
Enriched GO Terms of Interacting Partners?		Fatty Acid Beta-oxidation Lipid Metabolic Process Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Fatty Acid Metabolic Process Cellular Lipid Metabolic Process Carboxylic Acid Metabolic Process Cellular Lipid Catabolic Process Organic Acid Metabolic Process Monocarboxylic Acid Metabolic Process Small Molecule Metabolic Process Lipid Modification Carboxylic Acid Catabolic Process Very Long-chain Fatty Acid Metabolic Process Lipid Catabolic Process Peroxisome Organization Membrane Organization Mitochondrial Membrane Organization Protein Localization To Membrane Cerebellar Molecular Layer Development Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Cellular Response To Oxygen Levels Lipid Homeostasis Membrane Depolarization Vestibular Nucleus Development Negative Regulation Of Protein Homotetramerization Nitric Oxide Homeostasis Neuromuscular Process Oxidation-reduction Process Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Protein Import Into Peroxisome Matrix, Translocation Regulation Of Inward Rectifier Potassium Channel Activity Positive Regulation Of Cholesterol Homeostasis Protein Import Into Peroxisome Matrix, Docking Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Gamma-aminobutyric Acid Secretion Negative Regulation Of Pinocytosis Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Acetylcholine Secretion, Neurotransmission Mammary Gland Involution Organelle Organization Cytosolic Calcium Ion Homeostasis	Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process
Tagcloud ?		cannabinoid cannabinoids cb chemotactic chemotaxis clone confocal crosstalk cxcl12 cxcr4 cytoskeletal elucidation healing innovative jwh mcf7 metastasis mmtv modulate nt orthotopic p42 p44 possess psychoactive pymt syngenic tumorigenic wound	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Difference) ?		cannabinoid cannabinoids cb chemotactic chemotaxis clone confocal crosstalk cxcl12 cxcr4 cytoskeletal elucidation healing innovative jwh mcf7 metastasis mmtv modulate nt orthotopic p42 p44 possess psychoactive pymt syngenic tumorigenic wound	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Intersection) ?