RPL9 and SORBS2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RPL9	SORBS2
Gene Name		ribosomal protein L9	sorbin and SH3 domain containing 2
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit	Nucleus Plasma Membrane Actin Cytoskeleton Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Structural Constituent Of Ribosome RRNA Binding	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Adaptor Activity Structural Constituent Of Muscle Protein Domain Specific Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Actin Filament Organization Cell Adhesion Biological_process Cell Migration
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		21 interactors: CALCOCO2 CCDC184 CEP76 DHPS FAM9B HMBOX1 HOMEZ KXD1 MOCS2 MTUS2 PNMA2 RPS3 SORBS2 SPERT TIFA TRIM37 UBALD1 VCP ZBTB14 ZBTB7B ZBTB8A	35 interactors: ABL1 ABL2 ACTN1 ADAM15 AKT1 AKT2 ATPAF2 CBL DLGAP1 DLGAP2 DLGAP4 EFS EGFR FLOT1 MDM2 MLLT4 NCK2 NR1H2 PAK1 PAK2 PALLD PKM PTK2B PTPN12 RPL9 SEMA6A SH2D4A SYNJ1 TRAF4 VCL VPS37C WAS WASF1 YWHAE YWHAZ
Entrez ID		6133	8470
HPRD ID		04732	12473
Ensembl ID		ENSG00000163682	ENSG00000154556
Uniprot IDs		P32969 Q53Z07	B7Z3D7 B7Z997 O94875
PDB IDs		2CQL 3J3B	4IGZ
Enriched GO Terms of Interacting Partners?		Aggresome Assembly Regulation Of Centriole Replication Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Positive Regulation Of DNA N-glycosylase Activity Deoxyhypusine Biosynthetic Process From Spermidine Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Spermidine Catabolic Process Biosynthetic Process Histone H2A-K119 Monoubiquitination Transcription, DNA-templated Peptidyl-lysine Modification To Peptidyl-hypusine Positive Regulation Of NF-kappaB Transcription Factor Activity RNA Biosynthetic Process Polyamine Catabolic Process Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Centriole Replication Regulation Of Protein Deubiquitination Nitrogen Compound Metabolic Process Regulation Of Microtubule Cytoskeleton Organization Gene Expression Protein Hexamerization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of DNA Repair Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Microtubule-based Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Heterocycle Metabolic Process Positive Regulation Of Cell Death Translesion Synthesis Histone H2A Monoubiquitination Molybdopterin Cofactor Biosynthetic Process Molybdopterin Cofactor Metabolic Process Mo-molybdopterin Cofactor Biosynthetic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Histone H2A Ubiquitination Cytoplasmic Translation Negative Regulation Of Centrosome Duplication	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Component Movement Signaling Positive Regulation Of Transport Cell Communication Positive Regulation Of Organelle Organization Programmed Cell Death Regulation Of Cell Motility Cell Death Death Protein Autophosphorylation Regulation Of Cellular Component Organization Cell Activation Regulation Of Locomotion Regulation Of Cellular Ketone Metabolic Process Regulation Of Organelle Organization Positive Regulation Of Intracellular Transport Regulation Of Signaling Axonogenesis Cell Morphogenesis Involved In Differentiation Regulation Of Catalytic Activity Cellular Localization Regulation Of Signal Transduction Apoptotic Process Regulation Of Oxidoreductase Activity Cell Development Axon Development Positive Regulation Of Signal Transduction Fc Receptor Signaling Pathway Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cellular Localization Regulation Of Intracellular Transport Neuron Projection Development Innate Immune Response Actin Filament Organization Neuron Projection Morphogenesis Neurogenesis Positive Regulation Of Oxidoreductase Activity Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization Cell Projection Organization Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Cell Adhesion Movement Of Cell Or Subcellular Component Neuron Development Regulation Of Actin Cytoskeleton Organization
Tagcloud ?		acetyl acetyltransferases begins biogenesis biosynthesis building creb deacetylases e2f e2f1 hub lys nucleolar occupancy orchestrated pan ribosomal ribosome rpl4 rps rps24 rps27a rps6 rrna rrnas sp1 synchronized trimethyl
Tagcloud (Difference) ?		acetyl acetyltransferases begins biogenesis biosynthesis building creb deacetylases e2f e2f1 hub lys nucleolar occupancy orchestrated pan ribosomal ribosome rpl4 rps rps24 rps27a rps6 rrna rrnas sp1 synchronized trimethyl
Tagcloud (Intersection) ?