RPL9 and MOCS2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		RPL9	MOCS2
Gene Name		ribosomal protein L9	molybdenum cofactor synthesis 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit	Nucleus Cytoplasm Cytosol Molybdopterin Synthase Complex Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome RRNA Binding	Nucleotide Binding Molybdopterin Synthase Activity Identical Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Mo-molybdopterin Cofactor Biosynthetic Process Molybdopterin Cofactor Biosynthetic Process Small Molecule Metabolic Process
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Molybdenum cofactor biosynthesis Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in vitamin and cofactor metabolism Defects in cobalamin (B12) metabolism Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Molybdenum cofactor biosynthesis Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in vitamin and cofactor metabolism Defects in cobalamin (B12) metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: CALCOCO2 CCDC184 CEP76 DHPS FAM9B HMBOX1 HOMEZ KXD1 MOCS2 MTUS2 PNMA2 RPS3 SORBS2 SPERT TIFA TRIM37 UBALD1 VCP ZBTB14 ZBTB7B ZBTB8A	3 interactors: ABCF3 MOCS3 RPL9
Entrez ID		6133	4338
HPRD ID		04732	04750
Ensembl ID		ENSG00000163682	ENSG00000164172
Uniprot IDs		P32969 Q53Z07	O96007 O96033
PDB IDs		2CQL 3J3B	4AP8
Enriched GO Terms of Interacting Partners?		Aggresome Assembly Regulation Of Centriole Replication Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Positive Regulation Of DNA N-glycosylase Activity Deoxyhypusine Biosynthetic Process From Spermidine Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Spermidine Catabolic Process Biosynthetic Process Histone H2A-K119 Monoubiquitination Transcription, DNA-templated Peptidyl-lysine Modification To Peptidyl-hypusine Positive Regulation Of NF-kappaB Transcription Factor Activity RNA Biosynthetic Process Polyamine Catabolic Process Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Centriole Replication Regulation Of Protein Deubiquitination Nitrogen Compound Metabolic Process Regulation Of Microtubule Cytoskeleton Organization Gene Expression Protein Hexamerization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of DNA Repair Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Microtubule-based Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Heterocycle Metabolic Process Positive Regulation Of Cell Death Translesion Synthesis Histone H2A Monoubiquitination Molybdopterin Cofactor Biosynthetic Process Molybdopterin Cofactor Metabolic Process Mo-molybdopterin Cofactor Biosynthetic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Histone H2A Ubiquitination Cytoplasmic Translation Negative Regulation Of Centrosome Duplication	TRNA Wobble Position Uridine Thiolation Enzyme Active Site Formation Via L-cysteine Persulfide Protein Adenylylation Protein Urmylation TRNA Thio-modification TRNA Wobble Uridine Modification Molybdopterin Cofactor Biosynthetic Process Molybdopterin Cofactor Metabolic Process Mo-molybdopterin Cofactor Biosynthetic Process
Tagcloud ?		acetyl acetyltransferases begins biogenesis biosynthesis building creb deacetylases e2f e2f1 hub lys nucleolar occupancy orchestrated pan ribosomal ribosome rpl4 rps rps24 rps27a rps6 rrna rrnas sp1 synchronized trimethyl	1136a 667inscga aldehyde brazilian catabolism cofactor confirmation deficiencies deterioration detoxification encephalopathy geph homocysteine inborn mocs1 mocs3 molybdenum obtaining oxidase radiologic resembling specialized sulfite sulfur suox tentative turkish uric xanthine
Tagcloud (Difference) ?		acetyl acetyltransferases begins biogenesis biosynthesis building creb deacetylases e2f e2f1 hub lys nucleolar occupancy orchestrated pan ribosomal ribosome rpl4 rps rps24 rps27a rps6 rrna rrnas sp1 synchronized trimethyl	1136a 667inscga aldehyde brazilian catabolism cofactor confirmation deficiencies deterioration detoxification encephalopathy geph homocysteine inborn mocs1 mocs3 molybdenum obtaining oxidase radiologic resembling specialized sulfite sulfur suox tentative turkish uric xanthine
Tagcloud (Intersection) ?