RPGR and TUBG1

Number of citations of the paper that reports this interaction (PMID 16043481)
39

Data Source:
HPRD (in vivo)

		RPGR	TUBG1
Gene Name		retinitis pigmentosa GTPase regulator	tubulin, gamma 1
Image
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum	Pericentriolar Material Condensed Nuclear Chromosome Gamma-tubulin Complex Cytoplasm Centrosome Centriole Polar Microtubule Cytosol Cytoplasmic Microtubule Cell Leading Edge Nonmotile Primary Cilium Ciliary Basal Body Apical Part Of Cell Recycling Endosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Poly(A) RNA Binding	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding
	Biological Process	Intracellular Protein Transport Visual Perception Intraciliary Transport Cilium Assembly Eye Photoreceptor Cell Development Positive Regulation Of GTPase Activity Response To Stimulus	G2/M Transition Of Mitotic Cell Cycle Meiotic Spindle Organization Microtubule Cytoskeleton Organization Mitotic Cell Cycle Organelle Organization Microtubule Nucleation Cytoplasmic Microtubule Organization
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium G2/M Transition Anchoring of the basal body to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Recruitment of NuMA to mitotic centrosomes Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: DCTN1 DCTN2 IFT88 KIF3A KIFAP3 NPM1 PDE6D RPGRIP1 SLC25A10 SMC1A SMC3 TUBG1 YWHAE	24 interactors: BRCA1 CENPJ CNTN2 IKBKG KRT18 KRT19 MARK4 NAPG NDE1 OLA1 PCNT PIK3R1 PLK1 PXN RACGAP1 RASSF1 RNF19A RPGR SPATC1 TUBA1B TUBA3C TUBB4B TUBGCP3 TUBGCP4
Entrez ID		6103	7283
HPRD ID		02425	01853
Ensembl ID		ENSG00000156313	ENSG00000131462
Uniprot IDs		Q92834	P23258
PDB IDs		4JHN 4JHP	1Z5V 1Z5W 3CB2
Enriched GO Terms of Interacting Partners?		Microtubule-based Process Organelle Organization Microtubule Cytoskeleton Organization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Epidermal Stem Cell Homeostasis Cell Cycle Process G2/M Transition Of Mitotic Cell Cycle Spindle Organization Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Spindle Organization Cell Cycle Negative Regulation Of DNA Endoreduplication Establishment Of Vesicle Localization Plus-end-directed Vesicle Transport Along Microtubule Vesicle Localization Antigen Processing And Presentation Of Peptide Antigen Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of DNA Endoreduplication Antigen Processing And Presentation Cytoskeleton Organization Mitotic Sister Chromatid Cohesion Mitotic Nuclear Division Establishment Of Organelle Localization Establishment Of Localization In Cell Microtubule-based Transport Inner Ear Receptor Stereocilium Organization Cytoskeleton-dependent Intracellular Transport Organelle Localization Intracellular Transport Sister Chromatid Cohesion Cellular Localization Response To Stress Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Vesicle Transport Along Microtubule Cytoplasmic Microtubule Organization Meiotic Cell Cycle Melanosome Localization Inner Ear Receptor Cell Development Negative Regulation Of DNA Replication Organelle Transport Along Microtubule Cellular Pigmentation Inner Ear Receptor Cell Differentiation Microtubule-based Movement Regulation Of Endoribonuclease Activity	Microtubule-based Process Microtubule Cytoskeleton Organization Cytoskeleton Organization G2/M Transition Of Mitotic Cell Cycle Protein Polymerization Cellular Protein Complex Assembly Organelle Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle Cell Cycle Process Microtubule Nucleation Cellular Component Assembly Cellular Macromolecular Complex Assembly Microtubule Polymerization Mitotic Cell Cycle Process Protein Complex Assembly Mitotic Cell Cycle Microtubule Polymerization Or Depolymerization Centrosome Organization Microtubule Organizing Center Organization Organelle Assembly Regulation Of Protein Stability Centrosome Cycle 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Cell Division Movement Of Cell Or Subcellular Component Regulation Of Centriole Replication Regulation Of Cell Cycle Process Protein Stabilization Neural Precursor Cell Proliferation Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Cellular Localization Negative Regulation Of Cell Death Spindle Organization Growth Hormone Receptor Signaling Pathway Positive Regulation Of Protein Ubiquitination Cellular Response To Growth Hormone Stimulus Cytoskeleton-dependent Intracellular Transport Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Death Centrosome Duplication G2 DNA Damage Checkpoint Neuron Migration Regulation Of Microtubule-based Process Response To Growth Hormone Regulation Of Centrosome Duplication Positive Regulation Of Protein Metabolic Process
Tagcloud ?		acuity carriers decade erg examinations eye fields genotypically gtpase hemi identifiable kindred lys756del2aaag minimally oct ophthalmic orf15 perception phenotypically pigmentosa plottable profound puerto retinitis rican spearman teens visual	bipolar dcx disorganization dync1h1 electroporation ganglial gyral inputs interchangeability kif2a kif5c malformations mcd mcds polarization polymicrogyria postmitotic radial rescue round stereotyped tbr2 tuba1a tubb2b tubb3 tubb5 tubulin tubulins utero
Tagcloud (Difference) ?		acuity carriers decade erg examinations eye fields genotypically gtpase hemi identifiable kindred lys756del2aaag minimally oct ophthalmic orf15 perception phenotypically pigmentosa plottable profound puerto retinitis rican spearman teens visual	bipolar dcx disorganization dync1h1 electroporation ganglial gyral inputs interchangeability kif2a kif5c malformations mcd mcds polarization polymicrogyria postmitotic radial rescue round stereotyped tbr2 tuba1a tubb2b tubb3 tubb5 tubulin tubulins utero
Tagcloud (Intersection) ?