RPGR and RPGRIP1

Number of citations of the paper that reports this interaction (PMID 11104772)
47

Data Source:
BioGRID (two hybrid, affinity chromatography technology, pull down)
HPRD (in vivo, in vitro, two hybrid)

		RPGR	RPGRIP1
Gene Name		retinitis pigmentosa GTPase regulator	retinitis pigmentosa GTPase regulator interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum	Axoneme Photoreceptor Connecting Cilium
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Visual Perception Intraciliary Transport Cilium Assembly Eye Photoreceptor Cell Development Positive Regulation Of GTPase Activity Response To Stimulus	Visual Perception Eye Photoreceptor Cell Development Response To Stimulus Retina Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: DCTN1 DCTN2 IFT88 KIF3A KIFAP3 NPM1 PDE6D RPGRIP1 SLC25A10 SMC1A SMC3 TUBG1 YWHAE	24 interactors: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564
Entrez ID		6103	57096
HPRD ID		02425	05673
Ensembl ID		ENSG00000156313	ENSG00000092200
Uniprot IDs		Q92834	Q96KN7
PDB IDs		4JHN 4JHP
Enriched GO Terms of Interacting Partners?		Microtubule-based Process Organelle Organization Microtubule Cytoskeleton Organization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Epidermal Stem Cell Homeostasis Cell Cycle Process G2/M Transition Of Mitotic Cell Cycle Spindle Organization Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Spindle Organization Cell Cycle Negative Regulation Of DNA Endoreduplication Establishment Of Vesicle Localization Plus-end-directed Vesicle Transport Along Microtubule Vesicle Localization Antigen Processing And Presentation Of Peptide Antigen Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of DNA Endoreduplication Antigen Processing And Presentation Cytoskeleton Organization Mitotic Sister Chromatid Cohesion Mitotic Nuclear Division Establishment Of Organelle Localization Establishment Of Localization In Cell Microtubule-based Transport Inner Ear Receptor Stereocilium Organization Cytoskeleton-dependent Intracellular Transport Organelle Localization Intracellular Transport Sister Chromatid Cohesion Cellular Localization Response To Stress Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Vesicle Transport Along Microtubule Cytoplasmic Microtubule Organization Meiotic Cell Cycle Melanosome Localization Inner Ear Receptor Cell Development Negative Regulation Of DNA Replication Organelle Transport Along Microtubule Cellular Pigmentation Inner Ear Receptor Cell Differentiation Microtubule-based Movement Regulation Of Endoribonuclease Activity	Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Fatty Acid Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Apoptotic Signaling Pathway Negative Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Negative Regulation Of Lipid Biosynthetic Process Photoreceptor Cell Development Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Androgen Receptor Activity Negative Regulation Of Lipid Metabolic Process Regulation Of Fatty Acid Metabolic Process Regulation Of Cellular Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Neural Retina Development Negative Regulation Of Cilium Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Eye Development Signal Transduction By P53 Class Mediator Amacrine Cell Differentiation Cellular Response To Indole-3-methanol
Tagcloud ?		acuity carriers decade erg examinations eye fields genotypically gtpase hemi identifiable kindred lys756del2aaag minimally oct ophthalmic orf15 perception phenotypically pigmentosa plottable profound puerto retinitis rican spearman teens visual	ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cep76 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 tgl throw ttl
Tagcloud (Difference) ?		acuity carriers decade erg examinations eye fields genotypically gtpase hemi identifiable kindred lys756del2aaag minimally oct ophthalmic orf15 perception phenotypically pigmentosa plottable profound puerto retinitis rican spearman teens visual	ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cep76 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 tgl throw ttl
Tagcloud (Intersection) ?