RING1 and FBXO38

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RING1	FBXO38
Gene Name		ring finger protein 1	F-box protein 38
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Sex Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Speck PcG Protein Complex PRC1 Complex	Nucleus Cytoplasm
	Molecular Function	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Transcription, DNA-templated Anterior/posterior Pattern Specification Histone H2A Monoubiquitination Negative Regulation Of Transcription, DNA-templated Camera-type Eye Morphogenesis
Pathways		Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Wegener's granulomatosis ( 23740775)	Periodontal microbiota ( 22699663)
Protein-Protein Interactions		31 interactors: APP BMI1 CBX4 CBX6 CBX7 CBX8 E2F6 ELAC2 FBXO38 FHL1 HIST3H3 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 PHC1 PIK3R3 RB1 RNF2 RYBP UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K USP7 YAF2	6 interactors: ABL2 APP KLF7 PPM1G RING1 SOX30
Entrez ID		6015	81545
HPRD ID		03624	09775
Ensembl ID		ENSG00000204227	ENSG00000145868
Uniprot IDs		Q06587	Q6AZE0 Q6PIJ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein K48-linked Ubiquitination Histone Ubiquitination Chromatin Modification Chromatin Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Polyubiquitination Negative Regulation Of Gene Expression Transcription, DNA-templated Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process RNA Metabolic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Histone Modification Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Protein Monoubiquitination Nucleobase-containing Compound Metabolic Process Cellular Protein Modification Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Histone Monoubiquitination Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Protein K11-linked Ubiquitination Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Mitotic Cell Cycle Phase Transition Histone H2A Monoubiquitination Regulation Of Cell Cycle Phase Transition Cellular Protein Metabolic Process Regulation Of Metabolic Process Histone H2A Ubiquitination Organelle Organization Metabolic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Proteasomal Protein Catabolic Process	Neuron Remodeling Dendrite Development Neuron Maturation Axon Guidance Visual Learning Visual Behavior Neuromuscular Process Controlling Balance Dendrite Morphogenesis Associative Learning Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Neuromuscular Process Synaptic Growth At Neuromuscular Junction Learning Cell Morphogenesis Involved In Differentiation Regulation Of Protein Binding Cell Maturation Collateral Sprouting In Absence Of Injury Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Positive Regulation Of Interferon-gamma Secretion Collateral Sprouting Axon Midline Choice Point Recognition Neuron Development Anatomical Structure Morphogenesis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cell Morphogenesis Axon Choice Point Recognition Regulation Of Binding Learning Or Memory Bergmann Glial Cell Differentiation Neuron Differentiation Cell Projection Organization Cognition Cellular Calcium Ion Homeostasis Dendritic Spine Maintenance Calcium Ion Homeostasis Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of Interleukin-2 Secretion Locomotion Response To Light Stimulus Positive Regulation Of Non-canonical Wnt Signaling Pathway Substrate-dependent Cell Migration, Cell Extension Histone H2A Monoubiquitination Peptidyl-threonine Dephosphorylation Histone H2A Ubiquitination
Tagcloud ?		4h accomplish antioxidant ck cmv cortex creatine de dehydrogenase downregulated e3 electrophoresis extremely finger hselm lactate ldh ligase nontg secretase sel selenium selenoprotein selm spots synaptotagmin sytxv tg upregulated	18s actb ap3d1 bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Difference) ?		4h accomplish antioxidant ck cmv cortex creatine de dehydrogenase downregulated e3 electrophoresis extremely finger hselm lactate ldh ligase nontg secretase sel selenium selenoprotein selm spots synaptotagmin sytxv tg upregulated	18s actb ap3d1 bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Intersection) ?