RLN1 and RXFP1

Number of citations of the paper that reports this interaction (PMID 11809971)
82

Data Source:
HPRD (in vitro, in vivo)

		RLN1	RXFP1
Gene Name		relaxin 1	relaxin/insulin-like family peptide receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Hormone Activity	G-protein Coupled Receptor Activity Protein Binding Metal Ion Binding
	Biological Process	Signal Transduction Female Pregnancy	G-protein Coupled Receptor Signaling Pathway
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding Relaxin receptors
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: RXFP1	3 interactors: RLN1 RLN2 RLN3
Entrez ID		6013	59350
HPRD ID		01560	05975
Ensembl ID		ENSG00000107018	ENSG00000171509
Uniprot IDs		P04808	B3KV27 B4DGP2 Q59H16 Q9HBX9
PDB IDs			2JM4 2M7P
Enriched GO Terms of Interacting Partners?		Parturition Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Mammary Gland Development Connective Tissue Development Lung Development Respiratory Tube Development Respiratory System Development Extracellular Matrix Organization Extracellular Structure Organization	Female Pregnancy Reproductive Process
Tagcloud ?		11p12 14q24 6q12 9p24 abcd4 acyp1 amplifications apip cd109 cd274 commd9 coq6 cttn fjx1 hbld1 interscience jdp2 jpages ltbp2 myo6 otscc pdhx pinpointed ppfia1 q14 slc1a1 suppmat trim44 znf410	bioactive birth boars borne esr1 fed gata insl3 lactocrine leydig libitum neonatal nursed p450 p450scc pan pnd porcine proliferating reflected relaxin replacer sertoli steroidogenic testes testicular vegfa whereby
Tagcloud (Difference) ?		11p12 14q24 6q12 9p24 abcd4 acyp1 amplifications apip cd109 cd274 commd9 coq6 cttn fjx1 hbld1 interscience jdp2 jpages ltbp2 myo6 otscc pdhx pinpointed ppfia1 q14 slc1a1 suppmat trim44 znf410	bioactive birth boars borne esr1 fed gata insl3 lactocrine leydig libitum neonatal nursed p450 p450scc pan pnd porcine proliferating reflected relaxin replacer sertoli steroidogenic testes testicular vegfa whereby
Tagcloud (Intersection) ?