RXFP1 and RLN1

Number of citations of the paper that reports this interaction (PMID 11809971)
82

Data Source:
HPRD (in vitro, in vivo)

		RXFP1	RLN1
Gene Name		relaxin/insulin-like family peptide receptor 1	relaxin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region
	Molecular Function	G-protein Coupled Receptor Activity Protein Binding Metal Ion Binding	Hormone Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway	Signal Transduction Female Pregnancy
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding Relaxin receptors
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: RLN1 RLN2 RLN3	1 interactors: RXFP1
Entrez ID		59350	6013
HPRD ID		05975	01560
Ensembl ID		ENSG00000171509	ENSG00000107018
Uniprot IDs		B3KV27 B4DGP2 Q59H16 Q9HBX9	P04808
PDB IDs		2JM4 2M7P
Enriched GO Terms of Interacting Partners?		Female Pregnancy Reproductive Process	Parturition Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Mammary Gland Development Connective Tissue Development Lung Development Respiratory Tube Development Respiratory System Development Extracellular Matrix Organization Extracellular Structure Organization
Tagcloud ?		bioactive birth boars borne esr1 fed gata insl3 lactocrine leydig libitum neonatal nursed p450 p450scc pan pnd porcine proliferating reflected relaxin replacer sertoli steroidogenic testes testicular vegfa whereby	11p12 14q24 6q12 9p24 abcd4 acyp1 amplifications apip cd109 cd274 commd9 coq6 cttn fjx1 hbld1 interscience jdp2 jpages ltbp2 myo6 otscc pdhx pinpointed ppfia1 q14 slc1a1 suppmat trim44 znf410
Tagcloud (Difference) ?		bioactive birth boars borne esr1 fed gata insl3 lactocrine leydig libitum neonatal nursed p450 p450scc pan pnd porcine proliferating reflected relaxin replacer sertoli steroidogenic testes testicular vegfa whereby	11p12 14q24 6q12 9p24 abcd4 acyp1 amplifications apip cd109 cd274 commd9 coq6 cttn fjx1 hbld1 interscience jdp2 jpages ltbp2 myo6 otscc pdhx pinpointed ppfia1 q14 slc1a1 suppmat trim44 znf410
Tagcloud (Intersection) ?