RAD51D and XRCC3

Number of citations of the paper that reports this interaction (PMID 11744692)
24

Data Source:
HPRD (in vivo, in vitro)

		RAD51D	XRCC3
Gene Name		RAD51 paralog D	X-ray repair complementing defective repair in Chinese hamster cells 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Replication Fork Cytoplasm Centrosome Rad51B-Rad51C-Rad51D-XRCC2 Complex	Nucleus Replication Fork Cytoplasm Mitochondrion Rad51C-XRCC3 Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Four-way Junction DNA Binding DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Gamma-tubulin Binding	Four-way Junction DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Crossover Junction Endodeoxyribonuclease Activity
	Biological Process	Telomere Maintenance Double-strand Break Repair Via Homologous Recombination DNA Repair Reciprocal Meiotic Recombination Strand Invasion	Double-strand Break Repair Via Homologous Recombination DNA Catabolic Process, Endonucleolytic DNA Repair DNA Recombination Cellular Response To DNA Damage Stimulus Response To Organic Substance Regulation Of Centrosome Duplication Resolution Of Mitotic Recombination Intermediates Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: AMOTL2 BLM C1orf94 CEP57L1 IKZF1 IKZF3 KIFC3 KRT15 LNX1 LZTS2 PRDM14 RAD51B RAD51C SWSAP1 XRCC2 XRCC3 ZSWIM7	6 interactors: FANCG RAD51C RAD51D SWSAP1 ZNHIT3 ZSWIM7
Entrez ID		5892	7517
HPRD ID		04261	07201
Ensembl ID		ENSG00000185379	ENSG00000126215
Uniprot IDs		O75771	O43542 Q53XC8
PDB IDs		2KZ3
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Recombination DNA Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Organelle Organization Positive Regulation Of Mitotic Cell Cycle DNA Catabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Cell Cycle Nucleobase-containing Compound Metabolic Process Meiotic Nuclear Division Response To X-ray Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Meiotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Reciprocal Meiotic Recombination Positive Regulation Of Cell Cycle Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Neutrophil Differentiation Histone H3-R26 Methylation Inner Cell Mass Cell Fate Commitment Nitrogen Compound Metabolic Process Positive Regulation Of Cell Cycle Nucleic Acid Phosphodiester Bond Hydrolysis Microtubule-based Process Female Meiosis Sister Chromatid Cohesion Resolution Of Mitotic Recombination Intermediates Resolution Of Recombination Intermediates Strand Invasion DNA Catabolic Process, Endonucleolytic Protein Stabilization Zonula Adherens Maintenance Cellular Response To Camptothecin Cellular Response To Hydroxyurea Cellular Macromolecule Catabolic Process Regulation Of Lymphocyte Activation Meiosis I Lymphocyte Activation Response To Camptothecin Negative Regulation Of Mitotic Recombination Microtubule Cytoskeleton Organization	Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Repair DNA Recombination Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Reciprocal Meiotic Recombination Protein Stabilization Meiosis I Response To Stress Female Meiosis Sister Chromatid Cohesion Strand Invasion Regulation Of Protein Stability Meiotic Nuclear Division Meiotic Cell Cycle Nucleobase-containing Compound Metabolic Process Meiotic Sister Chromatid Cohesion Reproduction Cell Cycle Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cell Cycle Nitrogen Compound Metabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Spermatogenesis Male Gamete Generation Sister Chromatid Cohesion Male Meiosis I Cellular Response To Stimulus Female Meiotic Division Gamete Generation Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Male Meiosis Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Ovarian Follicle Development Telomere Maintenance Meiotic Chromosome Segregation Response To Stimulus Sister Chromatid Segregation DNA Catabolic Process, Endonucleolytic Chromosome Organization
Tagcloud ?		altogether anything atm brca2 brip1 chek2 confer dysfunctional exons germline harbor heritability hrr inherited junction missense palb2 paralogs postulated private silent splice substitutions tolerates unexplained variants xrcc2	additive allele applying became bonferroni correction d312n damaged dominant ercc2 ethnical exoi gg insignificant polymorphism polymorphisms r399q recessive remaining repair rs1799793 rs25487 russian russians snps tt xrcc1 xrcc2
Tagcloud (Difference) ?		altogether anything atm brca2 brip1 chek2 confer dysfunctional exons germline harbor heritability hrr inherited junction missense palb2 paralogs postulated private silent splice substitutions tolerates unexplained variants	additive allele applying became bonferroni correction d312n damaged dominant ercc2 ethnical exoi gg insignificant polymorphism polymorphisms r399q recessive remaining repair rs1799793 rs25487 russian russians snps tt xrcc1
Tagcloud (Intersection) ?		xrcc2