RAD51D and AMOTL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RAD51D	AMOTL2
Gene Name		RAD51 paralog D	angiomotin like 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Replication Fork Cytoplasm Centrosome Rad51B-Rad51C-Rad51D-XRCC2 Complex	Cytosol Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome
	Molecular Function	Four-way Junction DNA Binding DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Gamma-tubulin Binding	Protein Binding Identical Protein Binding
	Biological Process	Telomere Maintenance Double-strand Break Repair Via Homologous Recombination DNA Repair Reciprocal Meiotic Recombination Strand Invasion	Wnt Signaling Pathway Hippo Signaling
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: AMOTL2 BLM C1orf94 CEP57L1 IKZF1 IKZF3 KIFC3 KRT15 LNX1 LZTS2 PRDM14 RAD51B RAD51C SWSAP1 XRCC2 XRCC3 ZSWIM7	52 interactors: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MYO5B NDC80 NFIL3 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPP1 THRA TMCC2 TRAF2 TRIM27 WDYHV1 ZBED1 ZGPAT
Entrez ID		5892	51421
HPRD ID		04261	16485
Ensembl ID		ENSG00000185379	ENSG00000114019
Uniprot IDs		O75771	Q9Y2J4
PDB IDs		2KZ3
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Recombination DNA Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Organelle Organization Positive Regulation Of Mitotic Cell Cycle DNA Catabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Cell Cycle Nucleobase-containing Compound Metabolic Process Meiotic Nuclear Division Response To X-ray Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Meiotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Reciprocal Meiotic Recombination Positive Regulation Of Cell Cycle Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Neutrophil Differentiation Histone H3-R26 Methylation Inner Cell Mass Cell Fate Commitment Nitrogen Compound Metabolic Process Positive Regulation Of Cell Cycle Nucleic Acid Phosphodiester Bond Hydrolysis Microtubule-based Process Female Meiosis Sister Chromatid Cohesion Resolution Of Mitotic Recombination Intermediates Resolution Of Recombination Intermediates Strand Invasion DNA Catabolic Process, Endonucleolytic Protein Stabilization Zonula Adherens Maintenance Cellular Response To Camptothecin Cellular Response To Hydroxyurea Cellular Macromolecule Catabolic Process Regulation Of Lymphocyte Activation Meiosis I Lymphocyte Activation Response To Camptothecin Negative Regulation Of Mitotic Recombination Microtubule Cytoskeleton Organization	Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Protein Localization Histone H2B Ubiquitination Regulation Of Cellular Localization Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Polyubiquitination Mitotic Cell Cycle Organelle Organization Chromosome Organization Protein Ubiquitination Histone Monoubiquitination Negative Regulation Of Viral Transcription Cell Cycle Negative Regulation Of Transcription, DNA-templated Protein Modification By Small Protein Conjugation Regulation Of Establishment Of Protein Localization Protein K63-linked Ubiquitination Histone Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Protein Trimerization Negative Regulation Of Determination Of Dorsal Identity Regulation Of Metaphase Plate Congression Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Protein Metabolic Process Response To Organic Substance Cellular Response To Glucagon Stimulus
Tagcloud ?		altogether anything atm brca2 brip1 chek2 confer dysfunctional exons germline harbor heritability hrr inherited junction missense palb2 paralogs postulated private silent splice substitutions tolerates unexplained variants xrcc2	actin alanine amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap
Tagcloud (Difference) ?		altogether anything atm brca2 brip1 chek2 confer dysfunctional exons germline harbor heritability hrr inherited junction missense palb2 paralogs postulated private silent splice substitutions tolerates unexplained variants xrcc2	actin alanine amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap
Tagcloud (Intersection) ?