PTPRS and EEF1G

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PTPRS	EEF1G
Gene Name		protein tyrosine phosphatase, receptor type, S	eukaryotic translation elongation factor 1 gamma
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome	Nucleus Cytosol Membrane Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding	Translation Elongation Factor Activity Protein Binding
	Biological Process	Cell Adhesion Spinal Cord Development Cerebellum Development Hippocampus Development Cerebral Cortex Development Corpus Callosum Development Extracellular Matrix Organization Peptidyl-tyrosine Dephosphorylation	Translation Translational Elongation Response To Virus Gene Expression Cellular Protein Metabolic Process
Pathways		ECM proteoglycans	Translation Eukaryotic Translation Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: CHD3 EEF1G EGFR FEZ1 KAT5 KIAA1377 MOB4 PFN2 PPFIA1 PPFIA2 PPFIA3 PTN PTPRA PTPRD PTPRE PTPRM PTPRN RAB35 SETDB1 TUBB2A UBR1 UNC119 UTP14A	87 interactors: ABCC9 ADAP2 AKT1 ARF1 ARIH2 C11orf58 C1orf174 CARS CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EGFR EID2B ENOX1 FAM195A FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS KLHL18 LARS LZTS1 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SKIL SNAPIN SNRPD2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24
Entrez ID		5802	1937
HPRD ID		03344	11745
Ensembl ID		ENSG00000105426	ENSG00000254772
Uniprot IDs		Q13332 Q59FX6 Q8NHS7	P26641 Q53YD7
PDB IDs		2FH7 2YD2 2YD3 2YD9 4BPC	1PBU
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Peptidyl-tyrosine Dephosphorylation Glutamate Secretion Protein Dephosphorylation Acid Secretion Dephosphorylation Dicarboxylic Acid Transport Neurotransmitter Secretion Cellular Response To Estradiol Stimulus Regulation Of Neurotransmitter Levels Cellular Response To Estrogen Stimulus Positive Regulation Of Vasodilation Axon Guidance Amino Acid Transport Neuron Differentiation Neurotransmitter Transport Cell Projection Organization Signaling Cell Adhesion Cell Communication Regulation Of Vasodilation Neuron Projection Development Negative Regulation Of Epithelial Cell Migration Response To Estrogen Cell Projection Morphogenesis Cellular Protein Metabolic Process Alkanesulfonate Metabolic Process Negative Regulation Of Clathrin-mediated Endocytosis Cell Part Morphogenesis Secretion By Cell Enzyme Linked Receptor Protein Signaling Pathway Cell Cycle Cellular Response To Organic Substance Cell-cell Signaling Axonogenesis Cellular Response To Amino Acid Stimulus Regulation Of Stress Fiber Assembly Neuron Development Cellular Protein Modification Process Axon Development Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Cellular Response To Leucine Negative Regulation Of Caveolin-mediated Endocytosis Astrocyte Activation Dense Core Granule Maturation Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Regulation Of Dendrite Morphogenesis Chemotaxis Cell Cycle Process	Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Signal Transduction Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Transport Regulation Of Cell Development Chemotaxis Regulation Of Protein Kinase Activity Cell Cycle Regulation Of Endothelial Cell Migration Positive Regulation Of Mitochondrion Organization Regulation Of Kinase Activity Translation Negative Regulation Of Transferase Activity Regulation Of Neuron Differentiation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Neurogenesis Positive Regulation Of Transferase Activity Regulation Of Intracellular Transport Cellular Response To Mechanical Stimulus Nervous System Development Cellular Response To Growth Factor Stimulus Negative Regulation Of Kinase Activity MRNA Polyadenylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Binding Regulation Of Epithelial Cell Migration Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Metabolic Process MRNA 3'-end Processing Response To Growth Factor Regulation Of Signal Transduction Mitotic Cell Cycle Immune System Process Regulation Of Cell Projection Organization Response To UV-A Regulation Of Catalytic Activity
Tagcloud ?		cd24 cgrp chordoid codelink crb3 ependymal ependymomas hiomt hoxd13 krt18 opn4 phototransduction pineal pineoblastoma pineocytomas pou4f2 ppt ppts rarity rfx3 rgs16 sox4 spedf subcommissural tep1 tph ubec2 zfh4	4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct
Tagcloud (Difference) ?		cd24 cgrp chordoid codelink crb3 ependymal ependymomas hiomt hoxd13 krt18 opn4 phototransduction pineal pineoblastoma pineocytomas pou4f2 ppt ppts rarity rfx3 rgs16 sox4 spedf subcommissural tep1 tph ubec2 zfh4	4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct
Tagcloud (Intersection) ?