CD81 and IGSF8

Number of citations of the paper that reports this interaction (PMID 11673522)
21

Data Source:
HPRD (in vivo)

		CD81	IGSF8
Gene Name		CD81 molecule	immunoglobulin superfamily, member 8
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Vesicle Extracellular Vesicular Exosome	Plasma Membrane Membrane Integral Component Of Membrane Axon Synapse Extracellular Vesicular Exosome
	Molecular Function	Protein Binding MHC Class II Protein Complex Binding	Protein Binding
	Biological Process	Activation Of MAPK Activity Phosphatidylinositol Biosynthetic Process Protein Localization Cell Proliferation Positive Regulation Of Cell Proliferation Positive Regulation Of B Cell Proliferation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Phosphatidylinositol Metabolic Process Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Immune Response Regulation Of Cell Motility	Movement Of Cell Or Subcellular Component Single Fertilization Nervous System Development Skeletal Muscle Tissue Development Cell Proliferation Regulation Of Cell Motility
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: ADRB2 CD19 CD9 CSNK2B DLG5 HNRNPD IFITM1 IGSF8 INO80B ITGA4 JAK3 KIT MYOC PTGFRN RBBP6 RNF128 SHC1 TSPAN4 VKORC1 ZBTB16	9 interactors: A2M CD81 CD82 CD9 KRTAP10-3 KRTAP10-4 KRTAP10-7 KRTAP10-8 KRTAP10-9
Entrez ID		975	93185
HPRD ID		08924	09438
Ensembl ID		ENSG00000110651	ENSG00000162729
Uniprot IDs		E9PJK1 P60033	Q969P0
PDB IDs		1G8Q 1IV5 2AVZ
Enriched GO Terms of Interacting Partners?		Organ Development ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Proliferation System Development Regulation Of Immune Response Regulation Of Immune System Process Enzyme Linked Receptor Protein Signaling Pathway Developmental Process Positive Regulation Of Ossification B Cell Differentiation Multicellular Organismal Development Anatomical Structure Development Movement Of Cell Or Subcellular Component Regulation Of Cell Motility Response To Stress Negative Regulation Of Cell Proliferation Regulation Of Locomotion Cell Activation Regulation Of Cellular Component Movement B Cell Activation Epidermal Growth Factor Receptor Signaling Pathway Tissue Development Fibroblast Growth Factor Receptor Signaling Pathway Blood Coagulation Hemostasis Positive Regulation Of Signal Transduction Innate Immune Response Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Ossification Stem Cell Division Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Single Organismal Cell-cell Adhesion Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Cell Differentiation Bone Development Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Skeletal Muscle Hypertrophy Negative Regulation Of FasL Biosynthetic Process Zonula Adherens Assembly ERBB2-ERBB3 Signaling Pathway Mast Cell Proliferation Lymphocyte Differentiation	Platelet Degranulation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Platelet Activation Negative Regulation Of Complement Activation, Lectin Pathway Receptor-mediated Virion Attachment To Host Cell Exocytosis Response To Water Deprivation Virion Attachment To Host Cell Blood Coagulation Hemostasis Adhesion Of Symbiont To Host Secretion By Cell Regulation Of Body Fluid Levels Fusion Of Sperm To Egg Plasma Membrane Wound Healing Blood Coagulation, Intrinsic Pathway Paranodal Junction Assembly Negative Regulation Of Complement Activation Secretion Plasma Membrane Fusion Cell Activation Response To Wounding Myelin Assembly Regulation Of Immune Response Regulation Of Complement Activation Negative Regulation Of Innate Immune Response Positive Regulation Of B Cell Proliferation Viral Entry Into Host Cell Oligodendrocyte Development Entry Into Host Cell Regulation Of Humoral Immune Response Regulation Of B Cell Proliferation Regulation Of Lipid Kinase Activity Regulation Of Immune System Process Regulation Of Acute Inflammatory Response Positive Regulation Of B Cell Activation Oligodendrocyte Differentiation Vesicle-mediated Transport Regulation Of Cell Proliferation Extracellular Matrix Disassembly Glial Cell Development Interaction With Host
Tagcloud ?		000xg calreticulin centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vdac1 vesicle
Tagcloud (Difference) ?		000xg calreticulin centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vdac1 vesicle
Tagcloud (Intersection) ?