PRTFDC1 and TCL1A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRTFDC1	TCL1A
Gene Name		phosphoribosyl transferase domain containing 1	T-cell leukemia/lymphoma 1A
Image
Gene Ontology Annotations	Cellular Component	Cytosol	Endoplasmic Reticulum Cell Cortex Pronucleus
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Homodimerization Activity	Protein Binding
	Biological Process	Purine Ribonucleoside Salvage Adenine Salvage Guanine Salvage GMP Salvage IMP Salvage GMP Catabolic Process Hypoxanthine Metabolic Process	Multicellular Organismal Development Stem Cell Maintenance
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Adverse response to aromatase inhibitors ( 21172079 20876420)
Protein-Protein Interactions		12 interactors: DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 HPRT1 LGALS9B MCMBP NIF3L1 STAT5A TCL1A	21 interactors: AKT1 AKT2 AKT3 ALS2CR12 ATM CADPS CALCOCO2 CARD9 CEP55 DNMT3A GOLGA2 HIST3H2A LSM3 PRTFDC1 TCF4 TP53BP2 TRAF1 TTC33 TXLNA TXLNB WDR47
Entrez ID		56952	8115
HPRD ID		17917	01744
Ensembl ID		ENSG00000099256	ENSG00000100721
Uniprot IDs		Q9NRG1	P56279
PDB IDs		2JBH	1JSG
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mast Cell Differentiation GMP Salvage GMP Catabolic Process Guanine Salvage Glucosamine Catabolic Process FAD Biosynthetic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Regulation Of Mast Cell Differentiation Adenine Salvage Dihydrobiopterin Metabolic Process Hypoxanthine Salvage Development Of Secondary Male Sexual Characteristics Positive Regulation Of Dopamine Metabolic Process Hypoxanthine Metabolic Process Hypoxanthine Biosynthetic Process Negative Regulation Of Mast Cell Apoptotic Process GMP Biosynthetic Process Positive Regulation Of Glycogen (starch) Synthase Activity Creatinine Metabolic Process Regulation Of Mast Cell Apoptotic Process Purine Nucleoside Monophosphate Catabolic Process Glucosamine Metabolic Process Positive Regulation Of Mast Cell Proliferation Riboflavin Metabolic Process Isoleucine Metabolic Process Allantoin Metabolic Process Purine Ribonucleoside Salvage Taurine Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Response To Organonitrogen Compound Heterocycle Metabolic Process Negative Regulation Of Erythrocyte Differentiation Prolactin Signaling Pathway GMP Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Gamma-delta T Cell Activation Development Of Secondary Female Sexual Characteristics Valine Metabolic Process Creatine Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Natural Killer Cell Differentiation Succinate Metabolic Process Regulation Of Glycogen (starch) Synthase Activity Regulation Of Gamma-delta T Cell Differentiation Development Of Secondary Sexual Characteristics Purine Ribonucleoside Catabolic Process Luteinization Positive Regulation Of Glycogen Biosynthetic Process	Positive Regulation Of Glucose Metabolic Process Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Glycogen Metabolic Process Polysaccharide Metabolic Process Peripheral Nervous System Myelin Maintenance Positive Regulation Of Glycogen Biosynthetic Process Glial Cell Development Regulation Of Glucose Metabolic Process Regulation Of Fatty Acid Beta-oxidation Myelin Maintenance Mammary Gland Epithelial Cell Differentiation Energy Reserve Metabolic Process Negative Regulation Of Lipid Transport Glucose Metabolic Process Glycogen Biosynthetic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Response To Radiation Glial Cell Differentiation Regulation Of Fatty Acid Transport Cell Cycle Myelination In Peripheral Nervous System Positive Regulation Of Glucose Import Intrinsic Apoptotic Signaling Pathway Cellular Polysaccharide Biosynthetic Process Regulation Of Glycogen Metabolic Process Schwann Cell Development Positive Regulation Of Glucose Transport Regulation Of Extrinsic Apoptotic Signaling Pathway Polysaccharide Biosynthetic Process Regulation Of Cell Cycle Hexose Metabolic Process Apoptotic Process Negative Regulation Of Ion Transmembrane Transport Positive Regulation Of Intracellular Transport Cellular Carbohydrate Metabolic Process Regulation Of Myelination Gliogenesis Programmed Cell Death Schwann Cell Differentiation Monosaccharide Metabolic Process Negative Regulation Of Transmembrane Transport Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Glycogen Cell Differentiation Involved In Embryonic Placenta Development Cell Death Regulation Of Glucose Import Death Regulation Of Lipid Catabolic Process Positive Regulation Of Lipid Biosynthetic Process
Tagcloud ?			14q atm coexpression cutaneous cutis epidermotropism gains immunophenotype infiltrates institution integral inversion involvement irregular karyotype lactate lymphoid manifestations papules periadnexal perivascular pll plls prolymphocytic purpura rash rearrangement sized ulcers
Tagcloud (Difference) ?			14q atm coexpression cutaneous cutis epidermotropism gains immunophenotype infiltrates institution integral inversion involvement irregular karyotype lactate lymphoid manifestations papules periadnexal perivascular pll plls prolymphocytic purpura rash rearrangement sized ulcers
Tagcloud (Intersection) ?