PRKG1 and TRIM39-RPP21

Number of citations of the paper that reports this interaction (PMID 17601797)
1

Data Source:
BioGRID (two hybrid)

		PRKG1	TRIM39-RPP21
Gene Name		protein kinase, cGMP-dependent, type I	TRIM39-RPP21 readthrough
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane
	Molecular Function	CGMP-dependent Protein Kinase Activity Calcium Channel Regulator Activity Protein Binding ATP Binding CGMP Binding
	Biological Process	Neuron Migration Protein Phosphorylation Signal Transduction Blood Coagulation Dendrite Development CGMP-mediated Signaling Actin Cytoskeleton Organization Forebrain Development Regulation Of GTPase Activity Relaxation Of Vascular Smooth Muscle Negative Regulation Of Platelet Aggregation
Pathways		Ca2+ pathway Signaling by Wnt beta-catenin independent WNT signaling
Drugs
Diseases
GWAS		Asthma ( 21907864) Obesity-related traits ( 23251661)
Protein-Protein Interactions		34 interactors: ANXA7 CFTR CREB1 CRIP2 FAM124A FHOD1 GABRR1 GKAP1 GTF2I HDAC1 ITPR1 LASP1 LMO2 MRVI1 NPR1 PDE5A PLCB3 PPP1R12A PPP1R12B PPP1R17 PRKCA RAF1 RGS2 RYR1 SELL SEPT3 SF1 SPP1 TBXA2R TNNT1 TRIM39-RPP21 TRPC3 VASP ZNF646	1 interactors: PRKG1
Entrez ID		5592	202658
HPRD ID		08910
Ensembl ID		ENSG00000185532	ENSG00000248167
Uniprot IDs		Q13976	A6ZJ12
PDB IDs		1ZXA 3NMD 3OCP 3OD0 3OGJ
Enriched GO Terms of Interacting Partners?		Regulation Of Body Fluid Levels Hemostasis Regulation Of Muscle Contraction Blood Coagulation Negative Regulation Of Muscle Contraction Regulation Of Cardiac Muscle Hypertrophy Wound Healing Response To Wounding Cellular Response To Stimulus Response To Stimulus Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cellular Process Response To Organic Substance Cellular Cation Homeostasis Cellular Ion Homeostasis Cellular Calcium Ion Homeostasis Relaxation Of Muscle Calcium Ion Homeostasis Regulation Of Blood Vessel Size Regulation Of Tube Size Blood Circulation Signal Transduction Cellular Chemical Homeostasis Regulation Of Phospholipase Activity Platelet Activation Ion Homeostasis Neurotrophin TRK Receptor Signaling Pathway Vasodilation Neurotrophin Signaling Pathway Cellular Metal Ion Homeostasis Signaling Cell Communication Muscle System Process Cellular Homeostasis Metal Ion Homeostasis Relaxation Of Vascular Smooth Muscle Activation Of Phospholipase C Activity Positive Regulation Of Metabolic Process Regulation Of Smooth Muscle Contraction Relaxation Of Smooth Muscle Positive Regulation Of Phospholipase C Activity Regulation Of Ion Homeostasis Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Purine-containing Compound Cytosolic Calcium Ion Homeostasis Chemical Homeostasis Cellular Response To Fibroblast Growth Factor Stimulus Relaxation Of Cardiac Muscle	Relaxation Of Vascular Smooth Muscle CGMP-mediated Signaling Relaxation Of Smooth Muscle Negative Regulation Of Platelet Aggregation Negative Regulation Of Smooth Muscle Contraction Regulation Of Platelet Aggregation Negative Regulation Of Platelet Activation Negative Regulation Of Muscle Contraction Relaxation Of Muscle Cyclic-nucleotide-mediated Signaling Regulation Of Platelet Activation Vasodilation Regulation Of Smooth Muscle Contraction Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Blood Coagulation Negative Regulation Of Homotypic Cell-cell Adhesion Regulation Of Wound Healing Negative Regulation Of Cell-cell Adhesion Dendrite Development Second-messenger-mediated Signaling Regulation Of Muscle Contraction Neuron Migration Negative Regulation Of Cell Adhesion Muscle System Process Blood Circulation Regulation Of Cell-cell Adhesion Blood Coagulation Hemostasis Forebrain Development Regulation Of Cell Activation
Tagcloud ?		1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 ehhadh groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink scd1 sfa sorbs1 ufa underling unraveling
Tagcloud (Difference) ?		1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 ehhadh groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink scd1 sfa sorbs1 ufa underling unraveling
Tagcloud (Intersection) ?