PRKG1 and PPP1R17

Number of citations of the paper that reports this interaction (PMID 10051666)
7

Data Source:
HPRD (in vitro)

		PRKG1	PPP1R17
Gene Name		protein kinase, cGMP-dependent, type I	protein phosphatase 1, regulatory subunit 17
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane	Cellular_component
	Molecular Function	CGMP-dependent Protein Kinase Activity Calcium Channel Regulator Activity Protein Binding ATP Binding CGMP Binding	Protein Serine/threonine Phosphatase Inhibitor Activity
	Biological Process	Neuron Migration Protein Phosphorylation Signal Transduction Blood Coagulation Dendrite Development CGMP-mediated Signaling Actin Cytoskeleton Organization Forebrain Development Regulation Of GTPase Activity Relaxation Of Vascular Smooth Muscle Negative Regulation Of Platelet Aggregation	Central Nervous System Development Regulation Of Phosphatase Activity Intracellular Signal Transduction Negative Regulation Of Catalytic Activity
Pathways		Ca2+ pathway Signaling by Wnt beta-catenin independent WNT signaling
Drugs
Diseases
GWAS		Asthma ( 21907864) Obesity-related traits ( 23251661)
Protein-Protein Interactions		34 interactors: ANXA7 CFTR CREB1 CRIP2 FAM124A FHOD1 GABRR1 GKAP1 GTF2I HDAC1 ITPR1 LASP1 LMO2 MRVI1 NPR1 PDE5A PLCB3 PPP1R12A PPP1R12B PPP1R17 PRKCA RAF1 RGS2 RYR1 SELL SEPT3 SF1 SPP1 TBXA2R TNNT1 TRIM39-RPP21 TRPC3 VASP ZNF646	3 interactors: APP PRKACA PRKG1
Entrez ID		5592	10842
HPRD ID		08910	06820
Ensembl ID		ENSG00000185532	ENSG00000106341
Uniprot IDs		Q13976	O96001
PDB IDs		1ZXA 3NMD 3OCP 3OD0 3OGJ
Enriched GO Terms of Interacting Partners?		Regulation Of Body Fluid Levels Hemostasis Regulation Of Muscle Contraction Blood Coagulation Negative Regulation Of Muscle Contraction Regulation Of Cardiac Muscle Hypertrophy Wound Healing Response To Wounding Cellular Response To Stimulus Response To Stimulus Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cellular Process Response To Organic Substance Cellular Cation Homeostasis Cellular Ion Homeostasis Cellular Calcium Ion Homeostasis Relaxation Of Muscle Calcium Ion Homeostasis Regulation Of Blood Vessel Size Regulation Of Tube Size Blood Circulation Signal Transduction Cellular Chemical Homeostasis Regulation Of Phospholipase Activity Platelet Activation Ion Homeostasis Neurotrophin TRK Receptor Signaling Pathway Vasodilation Neurotrophin Signaling Pathway Cellular Metal Ion Homeostasis Signaling Cell Communication Muscle System Process Cellular Homeostasis Metal Ion Homeostasis Relaxation Of Vascular Smooth Muscle Activation Of Phospholipase C Activity Positive Regulation Of Metabolic Process Regulation Of Smooth Muscle Contraction Relaxation Of Smooth Muscle Positive Regulation Of Phospholipase C Activity Regulation Of Ion Homeostasis Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Purine-containing Compound Cytosolic Calcium Ion Homeostasis Chemical Homeostasis Cellular Response To Fibroblast Growth Factor Stimulus Relaxation Of Cardiac Muscle	Regulation Of Platelet Aggregation Regulation Of Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Regulation Of Blood Coagulation Positive Regulation Of Mitotic Cell Cycle Regulation Of Wound Healing Second-messenger-mediated Signaling Dendrite Development Regulation Of Protein Binding Cell Maturation Positive Regulation Of Dense Core Granule Biogenesis Regulation Of Muscle Contraction Locomotion Protein Phosphorylation Platelet Activation Regulation Of Peptidyl-tyrosine Phosphorylation Synaptic Growth At Neuromuscular Junction Histone H3-T6 Phosphorylation Movement Of Cell Or Subcellular Component Positive Regulation Of Cell Cycle Process Collateral Sprouting In Absence Of Injury Regulation Of Binding Positive Regulation Of Cell Cycle Cellular Calcium Ion Homeostasis Cell Development Calcium Ion Homeostasis Phosphorylation Collateral Sprouting Axon Midline Choice Point Recognition Response To Light Stimulus Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Cell-cell Adhesion Peptidyl-serine Autophosphorylation Axon Choice Point Recognition Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Protein Processing Cellular Metal Ion Homeostasis Regulation Of Mitotic Cell Cycle Nervous System Development Cellular Cation Homeostasis Forebrain Development
Tagcloud ?		1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 ehhadh groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink scd1 sfa sorbs1 ufa underling unraveling
Tagcloud (Difference) ?		1n9c acsl3 agpat3 bovinesnp50 bta1 c10 c12 c14 c18 chuk dgat1 echs1 ehhadh groundwork htr1b lipj lipk minpp1 mogat1 nfkb2 osbpl8 oxct1 plink scd1 sfa sorbs1 ufa underling unraveling
Tagcloud (Intersection) ?