PREP and NTS

Number of citations of the paper that reports this interaction (PMID 3525564)
14

Data Source:
HPRD (in vitro)

		PREP	NTS
Gene Name		prolyl endopeptidase	neurotensin
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Membrane	Extracellular Region Transport Vesicle
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Serine-type Peptidase Activity Serine-type Exopeptidase Activity	Neuropeptide Hormone Activity Protein Binding
	Biological Process	Proteolysis	Signal Transduction Regulation Of Blood Vessel Size
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: AGT BRCA1 KNG1 NTS OXT TAC1	9 interactors: ACE2 ARRB2 CPE MEP1A NLN NTSR1 NTSR2 PREP SORT1
Entrez ID		5550	4922
HPRD ID		02673	08878
Ensembl ID		ENSG00000085377	ENSG00000133636
Uniprot IDs		B2RAH7 P48147	P30990 Q6FH20
PDB IDs		3DDU	2LNE 2LNF 2LNG 2LYW 3F6K
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Renal Sodium Excretion Regulation Of Renal Sodium Excretion Regulation Of Excretion Blood Circulation Regulation Of Ion Homeostasis Positive Regulation Of Secretion Regulation Of Blood Vessel Size Regulation Of Tube Size Drinking Behavior Cellular Metal Ion Homeostasis Renal System Process Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Positive Regulation Of Digestive System Process Cellular Chemical Homeostasis Regulation Of Norepinephrine Secretion Ion Homeostasis Positive Regulation Of Cytosolic Calcium Ion Concentration Insemination Regulation Of Secretion Regulation Of Blood Pressure Cytosolic Calcium Ion Homeostasis Cellular Homeostasis Copulation Positive Regulation Of Transport Chemical Homeostasis Regulation Of Fatty Acid Biosynthetic Process Vasodilation Response To Salt Stress Cellular Calcium Ion Homeostasis Positive Regulation Of Blood Pressure Calcium Ion Homeostasis Regulation Of Synaptic Transmission Response To Abiotic Stimulus Mating Response To Activity Regulation Of Neurological System Process Positive Regulation Of Lipid Transport Smooth Muscle Contraction Regulation Of Heart Rate Homeostatic Process Positive Regulation Of Epithelial Cell Migration Regulation Of Fatty Acid Metabolic Process Response To Osmotic Stress Regulation Of Lipid Transport Response To Ammonium Ion Positive Regulation Of Inflammatory Response Feeding Behavior Uterine Smooth Muscle Contraction	Neuropeptide Signaling Pathway Proteolysis G-protein Coupled Receptor Signaling Pathway Peptide Hormone Processing Receptor Metabolic Process Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Adult Locomotory Behavior Digestion Angiotensin-mediated Drinking Behavior Angiotensin Catabolic Process In Blood Behavior Peptide Metabolic Process Multicellular Organismal Protein Catabolic Process Adult Behavior Receptor-mediated Virion Attachment To Host Cell Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Follicle-stimulating Hormone Signaling Pathway Insulin Processing Negative Regulation Of Smooth Muscle Cell Apoptotic Process Multicellular Organismal Protein Metabolic Process Hormone Metabolic Process Endosome Transport Via Multivesicular Body Sorting Pathway Receptor Biosynthetic Process Drinking Behavior Virion Attachment To Host Cell Positive Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Lipoprotein Lipase Activity Plasma Membrane To Endosome Transport Cell Surface Receptor Signaling Pathway Glucose Import Brain Renin-angiotensin System Locomotory Behavior Protein Processing Insulin Metabolic Process Adhesion Of Symbiont To Host Cellular Amide Metabolic Process Regulation Of Hormone Levels Angiotensin Maturation Regulation Of Angiotensin Metabolic Process Regulation Of Smooth Muscle Cell Apoptotic Process Peptide Catabolic Process Regulation Of Blood Volume By Renin-angiotensin G-protein Coupled Receptor Internalization Negative Regulation Of Interleukin-1 Beta Production Nerve Growth Factor Signaling Pathway Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Cardiac Left Ventricle Morphogenesis Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Synaptic Transmission, Dopaminergic
Tagcloud ?		abdominal airborne alcohol antisepsis antiseptic antiseptics bathing chg chlorhexidine clipping cloths droplet dual ebola flammable gluconate hair impregnated perineal ppe precautions preoperative preparation preps removal respirator vaginal washing words	acts autocrine cascades competing directed document embedded gxkkxxk homopolymeric localizes mediator mid motif mutagenesis nucleolin nucleolus paracrine parathyroid predict preservation pthrp representing ribonucleoprotein rna rnas salt secreted shared translated
Tagcloud (Difference) ?		abdominal airborne alcohol antisepsis antiseptic antiseptics bathing chg chlorhexidine clipping cloths droplet dual ebola flammable gluconate hair impregnated perineal ppe precautions preoperative preparation preps removal respirator vaginal washing words	acts autocrine cascades competing directed document embedded gxkkxxk homopolymeric localizes mediator mid motif mutagenesis nucleolin nucleolus paracrine parathyroid predict preservation pthrp representing ribonucleoprotein rna rnas salt secreted shared translated
Tagcloud (Intersection) ?