SHC3 and GOLGA2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SHC3	GOLGA2
Gene Name		SHC (Src homology 2 domain containing) transforming protein 3	golgin A2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytosol Plasma Membrane	Golgi Membrane Nucleus Golgi Apparatus Cis-Golgi Network ER To Golgi Transport Vesicle Golgi Cisterna Membrane
	Molecular Function	Signal Transducer Activity Protein Binding Protein Kinase Binding Receptor Tyrosine Kinase Binding	Protein Binding Protein Kinase Binding Syntaxin Binding
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Ras Protein Signal Transduction Central Nervous System Development Learning Or Memory Insulin Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Neurotrophin TRK Receptor Signaling Pathway	Mitotic Cell Cycle Negative Regulation Of Protein Binding
Pathways		Signalling to ERKs Signalling by NGF Insulin receptor signalling cascade SHC-mediated signalling SHC-related events triggered by IGF1R SHC-related events NGF signalling via TRKA from the plasma membrane IGF1R signaling cascade Signal attenuation Signalling to RAS Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) SHC-mediated signalling Signaling by Insulin receptor	Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Response to statin therapy (LDL-C) ( 22331829)
Protein-Protein Interactions		16 interactors: ALK APP ARHGAP32 AXL EGFR ERBB2 ERBB3 FLT4 GOLGA2 GRB2 KRT31 KRT40 NTRK1 NTRK2 RET SH3GL3	281 interactors: ABLIM1 ADAP1 AES AFF4 ALKBH3 ALS2CR11 AMOTL2 ANKRD11 ANKRD36BP1 APC ARID5A ARL16 ARL4A ARNT2 ARPC3 ATP6V1C2 ATP6V1D ATP6V1G1 ATXN7 BAHD1 BARD1 BCAS2 BCL6B BMS1P5 BYSL C12orf50 C14orf105 C1orf109 C1orf35 C20orf195 CBX8 CCAR1 CCDC146 CCDC150 CCDC17 CCDC53 CCDC67 CCDC70 CCDC87 CCDC94 CCHCR1 CCNC CCNH CDC20B CDC5L CDC73 CDK1 CDK18 CDKL3 CENPP CEP57L1 CHCHD2 CHCHD3 CINP CORO1A CRMP1 CSPP1 CUL5 CYB5R2 DAXX DCTN4 DCX DDX6 DGCR6 DLGAP5 DLX6-AS1 DMTN DTX2 EIF3G EP300 EXOSC5 FAM110A FAM124B FAM126B FAM184A FAM193B FAM207A FAM214A FAM50B FAM90A1 FBF1 FBXL18 FBXO28 FIP1L1 GATA2 GATAD2B GCC1 GEM GFAP GLYCTK GNG5 GORASP1 GORASP2 GPANK1 GPKOW GPS2 GSE1 GTPBP10 GZMA GZMK HAUS1 HDAC4 HOXB9 HRASLS5 HTRA1 HYLS1 IFT20 IFT27 INPP5J IQCE ISCU ITPKB ITSN2 KANK2 KANSL1 KAT5 KDM1A KIAA1217 KIFC3 KRT18 KRT6A KRT6B KRT6C LASP1 LATS1 LCOR LCP2 LENG1 LGALS3 LIMS2 LIN7A LINGO1 LMO1 LMO2 LMO4 LYPLA1 LYSMD1 MAB21L2 MAGOH MAGOHB MBD3 MCM10 MCM7 MFAP1 MID2 MORF4L1 MORF4L2 MORN3 MOS MSRB3 MTFR2 MVP MYEF2 NCF2 NDE1 NDEL1 NDN NEBL NME7 NOS3 NUDT21 NXT2 ORC1 PARD6B PATL1 PIAS2 PID1 PIK3R2 PIN1 PKN1 PKP4 POLDIP3 POM121 PPP1R16B PPP1R18 PPP2CA PQBP1 PRKAA1 PRKAB2 PRPF31 PSMA1 PSMA4 RAB1A RAB1B RAB2A RAB2B RAB33B RAB39A RAB39B RAB6A RBL1 RBM17 RBM39 RBM41 RCOR3 RGS8 RHNO1 RIBC1 RITA1 RNF135 RNF213 RNF214 RSPH14 RSRC2 RTP5 RUSC2 SAMD4A SAP30BP SCAF8 SCEL SCNM1 SECISBP2 SELV SH2D4A SH3RF2 SHC3 SLU7 SMARCE1 SMCP SNAP47 SNF8 SNRPB SNRPB2 SNRPC SNTA1 SNW1 SPATA2 SPATA22 SRSF2 STAMBPL1 STK25 STK26 SYT6 TBP TCEA2 TCEANC TCF19 TCL1A TEAD4 TFAP4 THAP7 TMED2 TPM1 TPX2 TRIM29 TRIM42 TSC22D4 TSSC4 TSSK3 TTC23 TTC25 TTC9C TUBGCP4 TXLNA UBE2I UBE2U UBE3C USO1 USP2 UTP14C VPS28 VPS37C WDYHV1 YTHDC1 ZBTB16 ZFC3H1 ZFP2 ZFYVE26 ZGPAT ZMAT2 ZNF124 ZNF250 ZNF410 ZNF414 ZNF417 ZNF488 ZNF572 ZNF581 ZNF587 ZNF594 ZNF774
Entrez ID		53358	2801
HPRD ID		12005	03989
Ensembl ID			ENSG00000167110
Uniprot IDs		Q92529	Q08379
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-tyrosine Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Signal Transduction Protein Phosphorylation Peptidyl-amino Acid Modification Regulation Of Signal Transduction Protein Autophosphorylation Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Neurogenesis Nervous System Development Regulation Of Signaling Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Phosphorylation Phosphatidylinositol-mediated Signaling Intracellular Signal Transduction Cellular Response To Growth Factor Stimulus Neuron Development Response To Growth Factor Regulation Of MAPK Cascade Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Regulation Of Protein Phosphorylation Generation Of Neurons Anatomical Structure Development Positive Regulation Of Protein Phosphorylation Neuron Differentiation Cell Surface Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Signal Transduction System Development Locomotion Cell Development Positive Regulation Of Synaptic Transmission, Glutamatergic Developmental Process Cellular Response To Organic Substance Positive Regulation Of Phosphorylation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Signaling Positive Regulation Of Protein Modification Process Regulation Of Cellular Protein Metabolic Process Cell Communication Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component	Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Cycle Organelle Organization Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process MRNA Metabolic Process MRNA Processing RNA Splicing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Mitotic Cell Cycle RNA Processing Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Metabolic Process Regulation Of Cellular Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Cycle MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Rab Protein Signal Transduction Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Cell Cycle Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Cellular Process Phagosome Maturation Chromosome Organization Cellular Component Assembly Chromatin Modification Chromatin Organization Mitotic Cell Cycle Process Mitotic Cell Cycle Phase Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Phase Transition
Tagcloud ?			5p accounts ameliorated ap1 canx chaperones clamp decoy deleterious deregulation disturbances electrical eliminated erg forced former h2o2 hek293 hsc70 micrornas mirnas myocytes patch reciprocal record seed sequestration trafficking upregulation
Tagcloud (Difference) ?			5p accounts ameliorated ap1 canx chaperones clamp decoy deleterious deregulation disturbances electrical eliminated erg forced former h2o2 hek293 hsc70 micrornas mirnas myocytes patch reciprocal record seed sequestration trafficking upregulation
Tagcloud (Intersection) ?